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Novel system for 3D reconstruction and examination of tissues at microscopic resolution

Researchers have developed a novel, easy-to-use system for three-dimensional (3D) reconstruction and examination of tissues at microscopic resolution, with the potential to significantly enhance the study of normal and disease processes, particularly those involving structural changes. The new approach, using conventional histopathological methods, is described in the May issue of The American Journal of Pathology.

17 Apr 2012

Inadequate sleep can increase risk of obesity

Can lack of sleep make you fat? A new paper which reviews the evidence from sleep restriction studies reveals that inadequate sleep is linked to obesity. The research, published in a special issue of the The American Journal of Human Biology, explores how lack of sleep can impact appetite regulation, impair glucose metabolism and increase blood pressure.

17 Apr 2012

Coronary stents do not increase risk of heart attack, death in people with metal allergies

Cardiologists have long grappled with how to best manage patients with coronary artery disease who report skin hypersensitivity to nickel or other metal components found in stents -- small tubes placed in narrowed or weakened arteries to help improve blood flow to the heart. But new Mayo Clinic research, published in the April 16, 2012, issue of Circulation: Cardiovascular Interventions, may help allay these concerns.

17 Apr 2012

Study finds lower cytokine levels in the plasma of children with autism

A University of Kansas Medical Center study found significantly lower levels of several cytokines, the immune system's messengers and regulators, in the plasma of children with autism disorder (AD) compared to that of unrelated healthy siblings from other families who had members with autism spectrum disorders.

17 Apr 2012

Study: Kidney cancer growth depends on autophagy

New research at the University of Cincinnati (UC) suggests that kidney cancer growth depends on autophagy, a complex process that can provide cells with nutrients from intracellular sources. Researchers say in certain circumstances autophagy can protect tumor cells from chemotherapy, allowing them to survive for long periods of time in a hidden, dormant, metastatic state.

17 Apr 2012

MTR can prevent cell death in patients with TBI

Wake Forest Baptist Medical Center researchers seeking a successful treatment for traumatic brain injury have found that the size and extent of damaged tissue can be reduced by using a new device to prevent cell death.

17 Apr 2012

Two related enzymes play a key role in development of T-ALL

Columbia University Medical Center (CUMC) scientists have demonstrated that two related enzymes - phosphoinositide-3 kinase (PI3K) gamma and delta - play a key role in the development of T-cell acute lymphoblastic leukemia (T-ALL), a highly aggressive childhood leukemia that is difficult to treat.

17 Apr 2012

UTHealth researcher studies novel cell therapy to prevent GVHD

A researcher at The University of Texas Health Science Center at Houston (UTHealth) is studying a novel cell therapy that could help avoid autoimmune problems after stem cell transplantation, as well as potentially treat other autoimmune diseases.

17 Apr 2012

ONO-4641 reduces number of lesions in people with MS

An investigational oral drug called ONO-4641 reduced the number of lesions in people with multiple sclerosis (MS), according to the results of a phase two clinical trial to be presented as Emerging Science at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012.

17 Apr 2012

Osprey Medical closes IPO raising of A$20 million

Osprey Medical Inc, has today announced that its Initial Public Offer (IPO) raising of A$20 million has closed. Osprey Medical’s Offer was well supported by institutional and retail investors in Australia, including founding investors CM Capital and Brandon Capital. The Initial Public Offer was underwritten by Shaw Corporate Finance.

17 Apr 2012

Gestational diabetes on the rise

Although the disease usually goes away after delivery, it can have permanent consequences. Not only can the mother be prone to develop diabetes later in life, but their babies are also at greater risk for chronic health problems.

16 Apr 2012

Cosmetics may contain chemicals that raise risk of obesity and diabetes

Scientists found that those who were exposed to phthalates, colourless man-made substances included in a variety of common consumer products, were more prone to weight gain. And subjects with even 'modest' levels of the substance in their bloodstream were twice as likely to develop diabetes.

16 Apr 2012

Men more likely to experience complications after brain or spinal surgery

Men are twice as likely as women to experience complications after brain or spinal surgery, reports a study in the April issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

16 Apr 2012

Rotavirus infects certain blood types

Whether you become infected by some strains of rotavirus may depend on your blood type.

16 Apr 2012

High blood sugar in combination with high insulin levels causes fatty deposits in the heart

The impaired substrate metabolism of diabetes patients is often expressed in an increase in fatty deposits in the cells of the heart muscle. Until now, the exact cause of this was unknown. Now, researchers at the MedUni Vienna in the Division of Endocrinology and Metabolism of MedUni Vienna in cooperation with the MR Centre of Excellence Vienna have shown that high blood sugar in combination with high levels of insulin - not an influx of fats - results in such deposits within a few hours.

16 Apr 2012

Neurological symptoms due to a bump on the head should not be ignored

When Dr. Irene Gatti de Leon slipped on the ice and bumped her head, she wasn't too concerned. But two months later, she began to experience weakness in her right leg and right arm while she and her husband were visiting their daughter in suburban Chicago.

16 Apr 2012

Panel discussion on personalized medicine at USciences

Advances in fields such as genetics and genomics have created new opportunities for personalized medicine applications in clinical practice and the healthcare delivery. This integration raises important questions about how personalized medicine can best help patients without increasing costs and improving health outcomes.

16 Apr 2012

Changes in thromboxane synthase may lead to hypertension in women with preeclampsia

Virginia Commonwealth University School of Medicine researchers have discovered that changes in the gene expression of a key enzyme may contribute to high blood pressure and increase susceptibility to forming blood clots in pregnant women with preeclampsia.

16 Apr 2012

DEP exposure suppresses function of phagocytic immune cells

A team of researchers, led by Dr. Stephan Schwander, of the University of Medicine and Dentistry of New Jersey - School of Public Health (UMDNJ-SPH), has determined a possible link between exposure to a common component of urban air pollution and a change in the function of important immune cells that protect against the bacteria that cause tuberculosis.

16 Apr 2012

Link between phthalates and risk of diabetes among seniors

There is a connection between phthalates found in cosmetics and plastics and the risk of developing diabetes among seniors. Even at a modest increase in circulating phthalate levels, the risk of diabetes is doubled. This conclusion is drawn by researchers at Uppsala University in a study published in the journal Diabetes Care.

16 Apr 2012