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Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

An interesting poster, just presented at the annual meeting of the American Society for Pharmacology and Experimental Therapeutics 2021, reports an association between the use of certain heart medications and the risk of COVID-19.

27 Apr 2021

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

The hormonal therapies used to treat many breast and prostate cancers raise the risk of a heart attack and stroke, and patients should be monitored regularly and receive treatment to reduce risk and detect problems as they occur.

26 Apr 2021

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

The first National Institutes of Health National Cancer Institute-funded clinical study examining stereotactic body radiotherapy (SBRT) in the treatment of oligometastatic breast, prostate, and non-small cell lung (NSCLC) cancers displayed evidence that SBRT can be safely used to treat patients who have multiple metastases.

23 Apr 2021

World Malaria Day 2021: An interview with Sir Brian Greenwood

News-Medical interviews Sir Brian Greenwood about raising awareness for malaria during the COVID-19 pandemic and achieving elimination of the disease.

23 Apr 2021

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location.

23 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

Researchers aim to better understand clinical features associated with COVID-19 mortality

To better understand the COVID-19 clinical feaures associated with mortality, an interdisciplinary team of researchers has investigated important factors and their influence on a patient’s death.

22 Apr 2021

Ultrasonically oscillating needles could improve cancer management

The diagnosis of diseases like cancer almost always needs a biopsy - a procedure where a clinician removes a piece of suspect tissue from the body to examine it, typically under a microscope.

21 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut.

20 Apr 2021

Chemical biomarker could be used to better manage treatments for COVID-19

Varying severity of COVID-19 symptoms in patients is reflected by levels of a chemical biomarker in their body which scientists say could be used to better manage treatments and other interventions, including vaccinations.

19 Apr 2021

Researchers test whether feces transplantation can help patients with cirrhosis of the liver

Researchers from Aarhus University and Aarhus University Hospital replace sick intestinal bacteria with intestinal bacteria from healthy donors in a treatment intended to help patients with cirrhosis of the liver. The Novo Nordisk Foundation supports the project with just over DKK 13 million.

19 Apr 2021

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Researchers at Albert Einstein College of Medicine have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer.

19 Apr 2021

Severity of COVID-19 symptoms is reflected by higher levels of chemical biomarker

19 Apr 2021

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

People with cystic fibrosis are living better and longer, and now investigators want to further enhance quality and longevity by better understanding the role of nutrition, body composition and exercise in their health across an increasing lifespan.

19 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Now, a team of researchers in China and Australia has shown that SARS-CoV-2 infection can affect bone marrow macrophage (BMM)-to-osteoclast differentiation, which may impact the skeletal system.

16 Apr 2021

Liver News and Research

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

World Malaria Day 2021: An interview with Sir Brian Greenwood

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

Clinical trial examines metabolic effects of natural compound NMN in people

Experimental drug reverses key symptoms of Alzheimer's disease in mice

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Researchers aim to better understand clinical features associated with COVID-19 mortality

Ultrasonically oscillating needles could improve cancer management

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Chemical biomarker could be used to better manage treatments for COVID-19

Researchers test whether feces transplantation can help patients with cirrhosis of the liver

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Severity of COVID-19 symptoms is reflected by higher levels of chemical biomarker

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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