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Trial of new type of drug that attacks amyloid

Neuroscientists at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia will begin a clinical trial testing a new type of drug that attacks amyloid, the protein substance that accumulates in the brains of Alzheimer’s disease patients.

4 Nov 2004

Discovery of internal molecular clock that governs the metabolism of sugars and fats within the body

Researchers at the University of Pennsylvania School of Medicine have discovered that components of the internal molecular clock of mammals have an important role in governing the metabolism of sugars and fats within the body.

4 Nov 2004

Pfizer licenses drug from University of Rochester for treatment of hot flashes

The University of Rochester has signed a license agreement with Pfizer which will allow Pfizer to market a specific class of non-hormonal drugs for the treatment of hot flashes associated with menopause.

4 Nov 2004

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Numerous compounds are examined by the National Cancer Institute (NCI) for their potential to prevent or treat cancer. One class of compounds, cyclooxygenase (COX) inhibitors, is currently being tested in both prevention and treatment clinical trials.

4 Nov 2004

FDA fast tracks investigational anti-cancer drug, phenoxodiol

Marshall Edwards today announced that the U.S. Food and Drug Administration (FDA) has granted the investigational anti-cancer drug, phenoxodiol, Fast Track status for its intended use in patients with recurrent ovarian cancer.

4 Nov 2004

British Medical Association calls on Health Secretary to deliver tough action to protect the nation's health

The British Medical Association today (4 November 2004) calls on Health Secretary John Reid to deliver tough action to protect the nation's health, as he finalises the White Paper on Public Health for England.

4 Nov 2004

European approval for Taxotere (docetaxel) in prostate cancer

Aventis, part of the sanofi-aventis Group announced today that the European Commission has approved Taxotere (docetaxel) Injection Concentrate for use in combination with prednisone as a treatment for men with androgen-independent (hormone- refractory) metastatic prostate cancer.

4 Nov 2004

FDA warns against use of Actra-Rx and Yilishen

The U.S. Food and Drug Administration has warned consumers not to purchase or to consume Actra-Rx or Yilishen, two products promoted and offered for sale on Web sites as "dietary supplements" for treating erectile dysfunction and enhancing sexual performance for men.

4 Nov 2004

Guidance for generic drugs

The U.S. Food and Drug Administration (FDA) has announced that a Guidance for Industry entitled "Listed Drugs, 30-Month Stays, and Approval of ANDAs and 505(b)(2) Applications Under Hatch-Waxman, as Amended by the Medicare Prescription Drug, Improvement, and Modernization Act of 2003

4 Nov 2004

Benefits to human health associated with the use of antibiotics in chicken may outweigh the potential risks

The potential benefits to human health associated with the use of antibiotics in chicken may outweigh the potential risks, according to a risk-benefit analysis conducted by a team of researchers led by Randall S. Singer, D.V.M., Ph.D., of the University of Minnesota College of Veterinary Medicine.

4 Nov 2004

Wyeth shows new Phase III data about its investigational antibiotic, tigecycline

Wyeth Pharmaceuticals recently presented exciting new Phase III data about its investigational antibiotic, tigecycline, based on a clinical trial in patients with complicated intra-abdominal infections (cIAI).

4 Nov 2004

Novel health food composition proves highly effective

A more than 50 % increase in the life span of Zucker rats, a commonly used animal model for human obesity, was seen by enrichment of unhealthy food with a novel combination of plant sterols and mineral nutrients.

4 Nov 2004

Mad cow disease prions can be removed from blood

New research results released today confirm that infectious variant Creutzfeldt-Jakob Disease (vCJD) prions that cause the human form of "mad cow disease" can be removed from blood.

From Pall Corporation 3 Nov 2004

Landmark case challenges safety of Atkins diet

West Palm Beach County Court Judge Susan Lubitz ruled today that the landmark lawsuit filed by former Atkins dieter and Florida businessman Jody Gorran will go forward.

3 Nov 2004

Researchers find that berries inhibit growth of harmful intestinal bacteria

A research project carried out by VTT Biotechnology and the University of Helsinki has found that cloudberries and raspberries contain a phenol, ellagic tannin, that inhibits the growth of intestinal bacteria.

2 Nov 2004

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

They found that the anti-cancer drug imatinib mesylate — commercially known as Gleevec and produced by Novartis Pharmaceuticals — can target a gene critical to controlling the disease process. Previously, there had been no treatment and patients usually did not survive beyond three years of diagnosis. Now the treatment is undergoing clinical trials at Mayo Clinic.

2 Nov 2004

Clinical trial of investigational oxygen-carrying blood substitute for use at the scene of injury

Loyola University Health System begins today the national clinical trial using PolyHeme®, an investigational oxygen-carrying blood substitute designed to increase survival of critically injured and bleeding trauma patients at the scene of injury.

1 Nov 2004

FDA allows health claims for olive oil

The U.S. Food and Drug Administration (FDA) has announced the availability of a qualified health claim for monounsaturated fat from olive oil and reduced risk of coronary heart disease (CHD).

1 Nov 2004

Studies show Pfizer's Azithromycin Microspheres effective as treatment for respiratory tract infections

Pfizer Inc.'s new investigational microsphere formulation of azithromycin, which is dosed as a one-time-only oral antibiotic, is comparable to other frequently prescribed treatments for some of the most common respiratory tract infections in adult patients.

1 Nov 2004

The microorganisms that normally live in the gut can increase body fat

The microorganisms that normally live in the gut can increase body fat, say researchers at Washington University School of Medicine in St. Louis. They found that gut microbes can open the "gates" fat uses to enter the body's fat cells.

1 Nov 2004