Protein C News and Research

RSS

Study finds smoking related to subset of colorectal cancers

Smoking puts older women at significant risk for loss of DNA repair proteins that are critical for defending against development of some colorectal cancers, according to research from a team led by Mayo Clinic scientists.

13 Apr 2008

Macadamia nuts decrease risk of heart disease

Macadamia nuts included in a heart healthy diet reduced low-density cholesterol (bad cholesterol) and should be included among nuts with qualified health claims, according to researchers.

13 Apr 2008

Discovery of small molecule that disrupts Ewing's sarcoma oncogene

Researchers at Georgetown University Medical Center have found a small molecule they say can block the action of the oncogene that causes Ewing's sarcoma, a rare cancer found in children and young adults.

13 Apr 2008

Iron deficiency cause

The discovery of a gene for a rare form of inherited iron deficiency may provide clues to iron deficiency in the general population – particularly iron deficiency that doesn't respond to iron supplements - and suggests a new treatment approach.

13 Apr 2008

The good and bad side of anti-cancer compounds

Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells.

11 Apr 2008

Protein sulfatase 2 a possible treatment target for liver cancer recurrence and survival

Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence.

11 Apr 2008

Researchers discover protein leiomodin promotes the assembly of an important heart muscle protein actin

Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin.

11 Apr 2008

Gene linked to inherited blood biomarker associated with asthma risk

Risk for developing asthma is linked to variants in a gene called CHI3L1, which can be measured by checking levels of an inherited blood protein regulated by that gene, according to new research sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

11 Apr 2008

Computational approaches to the role of epigenetic marks in transcription regulation

A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression.

11 Apr 2008

Blood vessels: The pied piper for growing nerve cells

Researchers at Johns Hopkins have discovered that blood vessels in the head can guide growing facial nerve cells with blood pressure controlling proteins.

11 Apr 2008

Biomarkers may reduce the need for biopsies and personalize transplant patient care

Data presented at the 28th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) suggest the potential of a significant impact of using biomarkers to reduce the need for biopsies and personalize transplant patient care.

11 Apr 2008

Researchers close in on origins of main ingredient of Alzheimer's plaques

The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned.

10 Apr 2008

Discovery of process behind heart muscle contraction

Researchers from the University of Pittsburgh and the University of Chicago were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction, as detailed in the April 11 cover story of the Journal of Biological Chemistry.

10 Apr 2008

Research using human embryonic stem cells reveals earliest step in human development

Researchers at Johns Hopkins have uncovered the molecular underpinnings of one of the earliest steps in human development using human embryonic stem cells.

10 Apr 2008

How protein sludge accumulates in Alzheimer's

Researchers have identified a key mechanism by which the protein sludge that kills brain cells accumulates in Alzheimer's disease (AD).

10 Apr 2008

Variation in CHI3L1 gene increases risk of asthma

A tiny variation in a gene known as CHI3L1 increases susceptibility to asthma, bronchial hyperresponsiveness and decline in lung function, researchers report early online in the New England Journal of Medicine.

10 Apr 2008

Low birth weight and heart problems

Researchers who have followed 5,840 people from before birth to the age of 31 have found evidence suggesting that small size at birth and excessive weight gain during adolescence and young adulthood may lead to low grade inflammation, which, in turn, is associated with an increased risk of developing heart disease.

10 Apr 2008