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Study reveals why paternal mitochondria must be removed during early development

It's one of the basic tenets of biology: We get our DNA from our mom and our dad.

9 Oct 2024

Tiny molecule offers hope in reducing opioid side effects

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression.

9 Oct 2024

Studying yeast could unlock new ways to make cancer cells more vulnerable

What can stressed yeast teach us about fundamental processes in the cell? A lot, according to scientists at the European Molecular Biology Laboratory (EMBL). The team studies, among other topics, how cells adapt to stress -- such as nutrient deprivation.

9 Oct 2024

Advances in technology shed light on cell function

Cells are the basic units of life — but when it comes to cells, if you think basic means simple, think again. Cells are complicated, with many millions of biochemical reactions per second seething within their confines. They also tend to be tiny, so it’s not easy to spy on their operations.

8 Oct 2024

High-fiber diets transform gut microbiome, improving health across multiple diseases

Researchers identified two competing guilds of gut bacteria, one beneficial and one harmful, which can predict health outcomes and treatment success in diseases like type 2 diabetes.

8 Oct 2024

Clonal competition assays reveal tumor cell resistance mechanisms

All cells within the same cancer are not the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical.

8 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

New insights into how stress affects pancreatic cells and diabetes risk

The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, such as inflammation and high blood sugar, contribute to the development of type 2 diabetes by overwhelming these cells.

8 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Study reveals how morphogens and cell adhesion create sharp tissue boundaries

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

8 Oct 2024

New insights into how DAPK3 regulates the migration of triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone.

8 Oct 2024

New triple-targeting pharmacological tool developed for cancer treatment

A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different therapeutic target within the cell.

8 Oct 2024

Understanding proteasome function in Trichomonas vaginalis for drug development

Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants.

8 Oct 2024

USC's Keck School of Medicine partners with StemCardia to advance heart failure treatment

The Keck School of Medicine of USC has launched a strategic collaboration with StemCardia, a biotechnology company, founded by a Keck School of Medicine faculty member, that develops cellular and genetic therapies to address heart failure.

8 Oct 2024

Study highlights rising rates of tick-borne parasitic disease in the United States

Rates of babesiosis, a tick-borne parasitic disease, increased an average of 9% per year in the United States between 2015 and 2022 and four in 10 patients were found to be co-infected with another tick-borne illness such as Lyme disease, according to a new study led by researchers at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.

8 Oct 2024

Electro-acupuncture shows promise in obesity management

A team of scientists led by Nanyang Technological University Singapore (NTU Singapore) and Hong Kong University (HKU) has found evidence that electro-acupuncture - a form of traditional Chinese medicine (TCM) treatment - could be used to manage obesity.

8 Oct 2024

Can multivitamins improve mood and reduce stress in older adults?

Researchers investigate the potential of multivitamin-mineral supplements to improve daily functioning among older adults.

8 Oct 2024

CrestOptics and Leica Microsystems announce strategic collaboration to expand capabilities of spinning disk microscopy

The collaboration between CrestOptics and Leica Microsystems combines CICERO spinning disk technology with THUNDER platform for superior microscopy solutions.

From CrestOptics 8 Oct 2024

Mosaic Therapeutics appoints Dr Barry Davies as CSO

Dr. Barry Davies joins Mosaic Therapeutics as CSO, bringing 25 years of drug discovery expertise to advance targeted oncology therapies and precision medicine.

8 Oct 2024

SCD health disparities tied to community factors

A new study finds that preschool-aged children with sickle cell disease (SCD) who live in food deserts and have limited access to transportation are at greater risk for acute complications and hospitalizations, despite receiving free evidence-based therapy and social support, according to results published today in Blood Advances.

8 Oct 2024