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Avexxin concludes second phase I/IIA study in patients suffering from mild-to-moderate psoriasis

Avexxin AS, a therapeutic company focusing on the discovery and development of novel small molecule therapeutics for patients suffering from chronic inflammatory conditions, announces the completion of a second phase I/IIa study showing Proof-of-Concept in man.

2 Jul 2015

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

Substituting deuterium for certain hydrogen atoms in molecules has been shown to enhance the metabolic properties of a number of drugs and provides a promising approach to the discovery and development of innovative drug products.

2 Jul 2015

Enhancements to Reaxys Medicinal Chemistry address workflow, data challenges of early drug discovery

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced enhancements to Reaxys Medicinal Chemistry that address the critical workflow and data challenges of early drug discovery.

30 Jun 2015

CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

Xybion Corporation, leading provider of preclinical R&D solutions announced today that CTI Biotechnology in Suzhou, China has implemented Xybion's Pristima 7 Preclinical Suite. Pristima® was selected after an exhaustive evaluation of top selling preclinical software systems on the market.

30 Jun 2015

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Creating bacterial "fight clubs" is an effective way to find new drugs from natural sources. That is the conclusion of a team of Vanderbilt chemists who have been exploring ways to get bacteria to produce biologically active chemicals that they normally hold in reserve. These compounds are called secondary metabolites.

30 Jun 2015

U.S. medical imaging market estimated to reach $82 million by 2019

Medical imaging is a notoriously data intensive field with its volume, variety and speed of data generation multiplying every day. Conventional tools are incapable of efficiently managing such large and complex datasets; posing limits on scalability, sustainability and usability. As the U.S. medical imaging field evolves from being not only data-intensive but also data-driven, big data tools are expected to better handle medical imaging, patient records, and improve workflow efficiency, diagnostic accuracy, treatment decisions and health management.

29 Jun 2015

Global GBM therapeutics market to expand at CAGR of 10.9% to $623 million by 2020

According to analysis from business intelligence provider GBI Research - Glioblastoma Multiforme Therapeutics in Major Developed Markets to 2020 - the value of the global Glioblastoma Multiforme (GBM) treatment market will expand at a rapid Compound Annual Growth Rate (CAGR) of 10.9%, from $301 million in 2013 to $623 million by 2020.

29 Jun 2015

Two physician-scientists in search for better Alzheimer's disease treatment

Two of the nation's leading physician-scientists in the search to better understand and treat Alzheimer's disease - William Mobley, MD, PhD, and Michael Rafii, MD, PhD - have been named interim co-directors of the Alzheimer's Disease Cooperative Study (ADCS), a major initiative formed in 1991 as a cooperative agreement between the National Institute on Aging (NIA) and the University of California, San Diego.

27 Jun 2015

UM SOM researcher uncovers new details about the body's response to flu virus

The flu virus can be lethal. But what is often just as dangerous is the body's own reaction to the invader. This immune response consists of an inflammatory attack, meant to kill the virus. But if it gets too aggressive, this counterattack can end up harming the body's own tissues, causing damage that can lead to death.

27 Jun 2015

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit.

26 Jun 2015

Diet, acidity of urine may influence susceptibility to urinary tract infections

The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.

26 Jun 2015

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Scientists from UCL (University College London) have designed a chemical compound that has reduced the growth of pancreatic cancer tumours by 80 percent in treated mice.

26 Jun 2015

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

Magnolias are prized for their large, colorful, fragrant flowers. Does the attractive, showy tree also harbor a potent cancer fighter?

26 Jun 2015

UK Court passes verdict in favor of Lilly relating to Alimta vitamin regimen patent claim

Eli Lilly and Company today announced that the Court of Appeal has ruled that the Alimta® (pemetrexed disodium) vitamin regimen patent would be indirectly infringed by a generic competitor that had stated its intent to market certain alternative salt forms of pemetrexed in the United Kingdom prior to the UK patent's expiration in June 2021.

25 Jun 2015

Breast cancer treatment market estimated to increase to over $13.1 billion by 2020

Analysis from business intelligence provider GBI Research - Breast Cancer Therapeutics in Major Developed Markets to 2020 - forecasts the breast cancer treatment market to increase in value from $9.2 billion in 2013 to more than $13.1 billion by 2020, representing a Compound Annual Growth Rate (CAGR) of 5.1%.

24 Jun 2015

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

US-Australian drug discovery company, Novogen Limited announced today that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals, the result of which it now has been fast-tracked by the Company to come into the clinic.

24 Jun 2015

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

In what may be a major leap forward in the quest for new treatments of the most common form of cardiovascular disease, scientists at Johns Hopkins report they have found a way to halt and reverse the progression of atherosclerosis in rodents by loading microscopic nanoparticles with a chemical that restores the animals’ ability to properly handle cholesterol.

24 Jun 2015

Dr. Maurizio D'Incalci to receive Pezcoller-Prodi Award in Scientific Career

Dr. Maurizio D'Incalci, MD, Ph.D., will receive an award in recognition of his scientific career at the new Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic organized by the European Association of Cancer Research, the American Association of Cancer Research and the Italian Cancer Society and that will be held in Florence, Italy, June 20-23.

23 Jun 2015

New 'smart insulin patch' could help patients suffering from diabetes

Painful insulin injections could become a thing of the past for the millions of Americans who suffer from diabetes, thanks to a new invention from researchers at the University of North Carolina and NC State, who have created the first "smart insulin patch" that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream whenever needed.

23 Jun 2015

Targeted molecular-imaging method could help identify early stages of prostate cancer

A targeted molecular-imaging method under development at Rochester Institute of Technology could help detect early stages of prostate cancer and improve image-directed biopsies.

23 Jun 2015

Compound News and Research

Avexxin concludes second phase I/IIA study in patients suffering from mild-to-moderate psoriasis

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

Enhancements to Reaxys Medicinal Chemistry address workflow, data challenges of early drug discovery

CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

U.S. medical imaging market estimated to reach $82 million by 2019

Global GBM therapeutics market to expand at CAGR of 10.9% to $623 million by 2020

Two physician-scientists in search for better Alzheimer's disease treatment

UM SOM researcher uncovers new details about the body's response to flu virus

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

Diet, acidity of urine may influence susceptibility to urinary tract infections

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

UK Court passes verdict in favor of Lilly relating to Alimta vitamin regimen patent claim

Breast cancer treatment market estimated to increase to over $13.1 billion by 2020

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

Johns Hopkins scientists use experimental therapy to reverse progression of atherosclerosis in rodents

Dr. Maurizio D'Incalci to receive Pezcoller-Prodi Award in Scientific Career

New 'smart insulin patch' could help patients suffering from diabetes

Targeted molecular-imaging method could help identify early stages of prostate cancer

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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