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Two UTHSC research teams receive CORNET Awards for novel projects

Two research teams at the University of Tennessee Health Science Center (UTHSC) have been awarded the 2022 UTHSC Collaborative Research Network (CORNET)-Functional Genomics Award. Each team will receive $50,000 to support their novel projects.

22 Jul 2022

Improving the immune defenses against blood cancer

For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer.

22 Jul 2022

Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

New AI software can create proteins that may be useful as vaccines, cancer treatments

Scientists have developed artificial intelligence software that can create proteins that may be useful as vaccines, cancer treatments, or even tools for pulling carbon pollution out of the air.

21 Jul 2022

A different approach to build a more durable, broadly effective COVID-19 vaccine

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.

21 Jul 2022

Booster vaccination counters the severity of Omicron breakthrough infections

Researchers assessed a panel of seven SARS-CoV-2 vaccines currently available globally and in the United States and immunity acquired through the previous infection against all Omicron subvariants.

21 Jul 2022

Pigment epithelium-derived factor ablations may lead to eye aging

Researchers identified that loss of pigment epithelium-derived factor (PEDF) may cause aging in the eye.

21 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 21 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

Researchers evaluate the efficacy of three- and four-dose regimens of a mRNA-based COVID-19 vaccine in reducing the risk of symptomatic infection.

20 Jul 2022

International Agency for Research on Cancer classifies firefighting as carcinogenic

The International Agency for Research on Cancer recently classified occupational exposure as a firefighter as carcinogenic, changing the previous classification of possibly carcinogenic.

20 Jul 2022

How the Omicron variant shifted the biology of SARS-CoV-2

Researchers discuss significant antigenic changes within the spike protein of new SARS-CoV-2 VOCs like the Omicron variant.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

A team of scientists from France has recently described the epidemiological and clinical consequences of a bat sarbecovirus infection in humanized mice.

20 Jul 2022

Neutralizing activity of skin-patch delivered subunit vaccine against SARS-CoV-2 variants

A new study involved an analysis of the serum from a previous study to determine neutralizing activity against new variants.

20 Jul 2022

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

Researchers reported mutations in SARS-CoV-2 Delta and Omicron variants of concern infection cases treated with neutralizing monoclonal antibodies.

20 Jul 2022

The durability of immunity and the likelihood of breakthrough infections following vaccination with four well-studied COVID-19 vaccines

Researchers compared the durability of vaccine-induced immunity and natural infection against COVID-19.

20 Jul 2022

Receptor News and Research

Two UTHSC research teams receive CORNET Awards for novel projects

Improving the immune defenses against blood cancer

Oligomeric molecular structure of the MOR-Gal1R complex revealed

New AI software can create proteins that may be useful as vaccines, cancer treatments

A different approach to build a more durable, broadly effective COVID-19 vaccine

Booster vaccination counters the severity of Omicron breakthrough infections

Pigment epithelium-derived factor ablations may lead to eye aging

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

Is monkeypox a global public-health emergency?

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

International Agency for Research on Cancer classifies firefighting as carcinogenic

How the Omicron variant shifted the biology of SARS-CoV-2

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

Neutralizing activity of skin-patch delivered subunit vaccine against SARS-CoV-2 variants

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

The durability of immunity and the likelihood of breakthrough infections following vaccination with four well-studied COVID-19 vaccines

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Researchers discover new key protection against COVID-19 in saliva

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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