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Study shows women with migraine history have rapid decline in estrogen levels

Researchers have long known that sex hormones such as estrogen play a role in migraine. But there's been little research on how that works. Do women with migraine have higher estrogen levels in general? Higher levels at the peak of the monthly cycle?

2 Jun 2016

Researchers call for more accurate renal assessment in stroke patients

Unrecognised renal insufficiency is common among patients with acute stroke and is associated with a significantly increased risk of in-hospital mortality or severe disability at discharge, say researchers.

2 Jun 2016

Renal function trajectories predict CV events in diabetes patients

Steeper declines in renal function over time are associated with greater increases in the risk of major cardiovascular events among patients with Type 2 diabetes, research shows.

1 Jun 2016

Sodium excretion linked to CVD risk in chronic kidney disease

High levels of sodium excretion are associated with a significantly increased risk of cardiovascular disease in patients with chronic kidney disease (CKD), US study findings indicate.

26 May 2016

Bare metal stents no longer advisable for high bleeding risk ACS patients

A polymer-free, drug-coated stent gives markedly better outcomes than a bare metal stent in patients with acute coronary syndromes and risk factors for bleeding, report researchers.

24 May 2016

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

New AVERT system can reduce radiographic dye volume in patients at risk of AKI

In the largest study of its kind, a new device has been found to significantly reduce the volume of radiographic dye without decreasing image quality in patients who are at risk of developing acute kidney injury (AKI) after undergoing a coronary angiography or percutaneous coronary intervention (PCI).

5 May 2016

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ...

18 Apr 2016

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging.

7 Apr 2016

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

University of Alabama at Birmingham researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using the laser-scanning method called MALDI tissue imaging to localize the changes.

24 Mar 2016

Real-world data confirm TDF efficacy for HBV

Treatment with tenofovir disoproxil fumarate elicits sustained virological responses and exhibits a favourable safety profile in a diverse population of patients with chronic hepatitis B virus infection, shows a French routine clinical practice study.

10 Mar 2016

FDA approves Allergan's sNDA to update label for DALVANCE (dalbavancin) for injection

Allergan plc, a leading global pharmaceutical company, today announced the U.S. Food and Drug Administration has approved the company's supplemental new drug application (sNDA) to update the label for DALVANCE (dalbavancin) for injection.

21 Jan 2016

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract.

23 Dec 2015

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body.

22 Dec 2015

Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

In a study released online today in The BMJ, researchers from Mayo Clinic report a national trend toward overtesting glycated hemoglobin (HbA1C) levels in adult patients with Type 2 diabetes.

9 Dec 2015

New article reveals link between poor kidney function, worse outcomes after heart surgery

Poor kidney function prior to heart surgery can lead to worse outcomes, higher surgical costs, and a longer hospital stay, according to an article posted online today by The Annals of Thoracic Surgery.

9 Dec 2015

Personalised peptide vaccination promising in bladder cancer

Metastatic bladder cancer patients who have progressed on first-line platinum-based chemotherapy could derive survival benefits from personalised peptide vaccination, according to phase II trial results.

27 Nov 2015

U.S. adults who use smokeless tobacco products have higher levels of nicotine, carcinogen

U.S. adults who used only smokeless tobacco products had higher levels of biomarkers of exposure to nicotine and a cancer-causing toxicant -- the tobacco-specific nitrosamine NNK -- compared with those who used only cigarettes

19 Nov 2015

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.

10 Nov 2015