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Biologic, environmental factors may be possible culprits for racial disparities in CKD progression

Although black and Hispanic veterans with chronic kidney disease are more likely than white patients to see a kidney specialist- a nephrologist- they are more likely to suffer disease progression from early stage to advanced kidney disease, reports a study published this month in the Journal of the American Society of Nephrology from researchers at the Perelman School of Medicine at the University of Pennsylvania.

24 Aug 2018

A late-life surprise: Taking care of frail, aging parents

"This won't go on for very long," Sharon Hall said to herself when she invited her elderly mother, who'd suffered several small strokes, to live with her.

23 Aug 2018

Genome sequences of ape parasites provide insights on origin and early evolution of malaria

The genome sequences of ape parasites related to Plasmodium vivax (P. vivax), the main source of mosquito-borne malaria outside Africa, provide insights on the origin and early evolution of the human parasite.

21 Aug 2018

Penn researchers develop first mouse model of idiopathic pulmonary fibrosis

The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening condition in which the lungs become scarred and breathing is increasingly difficult – has been the inability to fully model the disease in animals, limiting the ability to observe and understand the disease.

16 Aug 2018

Diabetes epidemic in Guatemala driven by aging, not obesity

The diabetes epidemic in Guatemala is worse than previously thought: more than 25 percent of its indigenous people, who make up 60 percent of the population, suffer from type 2 diabetes or pre-diabetes, suggests a new study published in PLOS ONE from researchers at the Penn Center for Global Health, in collaboration with the University of San Carlos in Guatemala City and the Hospitalito Atitlán.

14 Aug 2018

‘No one is ever really ready’: Aid-in-dying patient chooses his last day

In the end, it wasn't easy for Aaron McQ to decide when to die. The 50-year-old Seattle man — a former world traveler, triathlete and cyclist — learned he had leukemia five years ago, followed by an even grimmer diagnosis in 2016: a rare form of amyotrophic lateral sclerosis, or ALS.

14 Aug 2018

PARP inhibitors show promise for treating and preventing brain disorders

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis, also called Lou Gehrig's disease, and some forms of frontotemporal degeneration, by halting the misplacement of specific proteins that affect nerve cells, according to a study published in Molecular Cell by researchers in the the School of Arts and Sciences and the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2018

Penn study suggests method to measure and operationalize inclusion in heath care organizations

The importance of an inclusive workforce culture in health care is key to advancing scientific inquiry, improving the quality of care, and optimizing patient satisfaction.

3 Aug 2018

Study identifies brain-based dimensions of mental health disorders using machine learning

A new study using machine learning has identified brain-based dimensions of mental health disorders, an advance towards much-needed biomarkers to more accurately diagnose and treat patients.

2 Aug 2018

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications this month by researchers from the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2018

FDA approves first ever non-surgical treatment for rare neuroendocrine cancers

The U.S. Food and Drug Administration has approved the first ever non-surgical treatment for the rare neuroendocrine cancers pheochromocytoma and paraganglioma.

31 Jul 2018

Missed visits, uncontrolled pain and fraud: report says hospice lacks oversight

Elderly patients spent over two weeks in uncontrolled pain or respiratory distress. Acute care was rare on weekends. And recruiters went door to door pitching fraudulent schemes, luring healthy patients to sign up for hospice in exchange for free housecleaning and medicine.

31 Jul 2018

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair.

28 Jul 2018

Pairing online patient dashboard with 'nudges' to doctors triples statin prescribing rates

Pairing an online patient dashboard with "nudges" to doctors tripled statin prescribing rates in a clinical trial led by Penn Medicine researchers.

27 Jul 2018

Diet-induced obesity synchronizes opposing liver fat metabolic processes in mice

Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned, according to a new study published in Cell by researchers in the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2018

ProMedica announces addition of HCR ManorCare operations to redefine care for seniors

ProMedica, a mission-based, not-for-profit healthcare system focused on improving health and well-being, today announced the finalization of the transaction that adds HCR ManorCare operations to the ProMedica organization.

27 Jul 2018

No gaps in understanding: Here’s your primer on Medigap coverage

Every year, older adults can opt out of a Medicare Advantage plan and opt in to original Medicare during open enrollment season, which begins on Oct. 15.

26 Jul 2018

Reduced plasmalogen level may increase risk of Alzheimer's disease, shows study

Reduced levels of plasmalogens - a class of lipids created in the liver that are integral to cell membranes in the brain - are associated with an increased risk of Alzheimer's Disease, according to new research presented this week at the Alzheimer's Association International Conference 2018 by Mitchel A. Kling, MD, an associate professor of Psychiatry in the Perelman School of Medicine at the University of Pennsylvania and the Veterans Affairs Medical Center.

25 Jul 2018

Large-scale DNA sequence data on Alzheimer's disease to be made available to investigators

The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site will begin making large-scale DNA sequence data available to investigators.

24 Jul 2018

Study: Greening vacant urban land reduces feelings of depression for surrounding residents

Greening vacant urban land significantly reduces feelings of depression and improves overall mental health for the surrounding residents, researchers from the Perelman School of Medicine and the School of Arts & Sciences at the University of Pennsylvania and other institutions show in a new randomized, controlled study published in JAMA Network Open.

20 Jul 2018

Hospice News and Research

Biologic, environmental factors may be possible culprits for racial disparities in CKD progression

A late-life surprise: Taking care of frail, aging parents

Genome sequences of ape parasites provide insights on origin and early evolution of malaria

Penn researchers develop first mouse model of idiopathic pulmonary fibrosis

Diabetes epidemic in Guatemala driven by aging, not obesity

‘No one is ever really ready’: Aid-in-dying patient chooses his last day

PARP inhibitors show promise for treating and preventing brain disorders

Penn study suggests method to measure and operationalize inclusion in heath care organizations

Study identifies brain-based dimensions of mental health disorders using machine learning

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

FDA approves first ever non-surgical treatment for rare neuroendocrine cancers

Missed visits, uncontrolled pain and fraud: report says hospice lacks oversight

Drug that treats diabetes found to exert powerful check on macrophages in controlling inflammation

Pairing online patient dashboard with 'nudges' to doctors triples statin prescribing rates

Diet-induced obesity synchronizes opposing liver fat metabolic processes in mice

ProMedica announces addition of HCR ManorCare operations to redefine care for seniors

No gaps in understanding: Here’s your primer on Medigap coverage

Reduced plasmalogen level may increase risk of Alzheimer's disease, shows study

Large-scale DNA sequence data on Alzheimer's disease to be made available to investigators

Study: Greening vacant urban land reduces feelings of depression for surrounding residents

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