Immune Response News and Research

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Scientists discover thymic M cells

It came as a surprise to Professor David Lo and his graduate student Diana Del Castillo when they were recently consulted by researchers in Israel for their expertise on specialized cells called Microfold cells, or M cells, which are mostly known for their presence in the intestinal epithelium.

7 Sep 2023

Immune cells can create their own chemical cues to navigate in complex environments

Human immune cells are capable of coordinating their own movement more independently than previously thought. InFLAMES researcher Jonna Alanko has discovered that immune cells do not just passively follow the chemical cues in their environment.

7 Sep 2023

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

OHSU scientists discover new avenue of cell death in Alzheimer's disease and vascular dementia

Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia.

5 Sep 2023

Scientists develop new technique to study sugars on immune cells

Everyone loves a sweet treat, even our cells. While we typically think of sugar as a component of our diet that gives us energy, sugars are also very important in guiding the activity of our cells.

5 Sep 2023

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Researchers characterized two novel SARS-CoV-2 XBB variants, EG.5.1 and XBB.2.3.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Study sheds light on immune cells' ability to collectively migrate through complex environments

When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments.

1 Sep 2023

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

Research funded by the National Institute for Health and Care Research (NIHR) has shown that higher levels of inflammation in the blood of patients with obesity undergoing bariatric surgery predicts poorer weight loss six months after the procedure.

31 Aug 2023

New insights into how lung cells detect influenza virus

Researchers from Trinity College Dublin have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.

31 Aug 2023

Scientists delve deeper into how vaccines work against leishmaniasis

Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.

31 Aug 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."

31 Aug 2023

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

The study finds that the fourth dose of the COVID-19 mRNA vaccine significantly boosts neutralizing antibody levels in the elderly, providing enhanced protection against new SARS-CoV-2 variants like Omicron. This supports the efficacy of booster shots for older populations in combating COVID-19.

31 Aug 2023

New omicron variants can reinfect people who were infected with earlier variants

The omicron variants of the SARS-CoV-2 virus, which have rapidly spread around the world over the past year, latch onto our cells more tightly, invade them more efficiently, and elude many of the antibodies induced by previous infections and vaccines.

30 Aug 2023

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

Novavax's protein-based COVID vaccine induces broad functional immune response against XBB subvariants, data shows

Novavax, Inc., a global company advancing protein-based vaccines with its novel Matrix-M™ adjuvant, today announced that its updated protein-based XBB COVID vaccine candidate induced neutralizing antibody responses to the EG.5.1 and XBB.1.16.6 subvariants in small animal and non-human primate studies.

25 Aug 2023

Immune Response News and Research

Scientists discover thymic M cells

Immune cells can create their own chemical cues to navigate in complex environments

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

Early viral exposure in mice weakens vaccine response, raising questions for human studies

OHSU scientists discover new avenue of cell death in Alzheimer's disease and vascular dementia

Scientists develop new technique to study sugars on immune cells

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Study sheds light on immune cells' ability to collectively migrate through complex environments

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

New insights into how lung cells detect influenza virus

Scientists delve deeper into how vaccines work against leishmaniasis

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

New omicron variants can reinfect people who were infected with earlier variants

Gene variant protects against Alzheimer's and Parkinson's diseases

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Light-driven bacteria could be used to target and kill cancer cells

Novavax's protein-based COVID vaccine induces broad functional immune response against XBB subvariants, data shows

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