Induced Pluripotent Stem Cells News and Research

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Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Nanotechnology could boost stem cell transplantation research

Nanotechnology developed at Rutgers University-New Brunswick could boost research on stem cell transplantation, which may help people with Alzheimer's disease, Parkinson's disease, other neurodegenerative diseases and central nervous system injuries.

14 Aug 2019

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset.

14 Aug 2019

Novel dual approach can be a promising way to enhance cardiac repair

As a medical emergency caused by severe cardiovascular diseases, myocardial infarction (MI) can inflict permanent and life-threatening damage to the heart.

12 Aug 2019

Researchers seek to understand the regenerative potential of newborn mammalian hearts

Unlike lower vertebrates, mammals are unable to repair their adult hearts after injuries that include heart attacks. This inability in humans leads to heart failure -- a deadly and costly disease that affects more than 5 million Americans.

10 Aug 2019

New method to enhance heart-attack repair using stem cell-derived cardiomyocytes

The heart cannot regenerate muscle tissue after a heart attack has killed part of the muscle wall. That dead tissue can strain surrounding muscle, leading to a lethal heart enlargement.

8 Aug 2019

New 3D-cardiac tissue platform can predict how heart responds to drugs

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans.

7 Aug 2019

First-of-its-kind study in space station seeks to find causes of major diseases

High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking for what triggers these diseases by studying how nerve and immune brain cells interact.

1 Aug 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

New biomaterial could encapsulate and protect implanted insulin-producing cells

Transplanting insulin-producing pancreatic cells into people with type 1 diabetes has emerged as a ground-breaking treatment for millions of patients over the past few decades.

4 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

Scientists suggest possible cell-based therapy for premature infants with rare lung condition

Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia, which in the most severe cases can lead to lifelong breathing problems and even death.

27 Jun 2019

New method allows cells to be produced in shorter time and with greater success

A recent study published in the April 8 issue of Nature Chemical Biology improves on the "Cellular Reprogramming" method developed by Nobel Laureate in Medicine and Physiology Prof. Shinya Yamanaka, making it possible to produce cells in a considerably shorter time and with greater success. Yamanaka's method, which is referred to as "Cellular Reprogramming", obtains pluripotent cells, similar to the ones we know exist in the very early stages of the embryo

14 Jun 2019

Researchers develop first blood-brain barrier chip using stem cells

Researchers at Ben-Gurion University of the Negev and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier, creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.

13 Jun 2019

URMC biotech start-up receives funding to develop cell-based therapies for neurological disorders

Oscine Therapeutics, a new biotechnology company based on discoveries made and developed at the University of Rochester Medical Center has received a significant multi-year investment to support both research and development of cell-based therapies for neurological disorders.

11 Jun 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Study reveals how genetic message to produce healthy heart tissue is altered during stress, aging

Researchers at the Fralin Biomedical Research Institute at Virginia Tech Carilion have revealed how a genetic message to produce healthy heart tissue is altered in the body during stress and aging to contribute to sudden cardiac death.

29 May 2019

Stem cell study reveals the harmful effects of flavored e-cigarette liquids

Your favorite vape flavor may be more harmful than the nicotine itself. Using stem cells to investigate the impact of e-liquids on cardiovascular disease, a new study has revealed the harmful effects of flavored e-cigarette liquids and e-cigarette use.

28 May 2019

Acute exposure to flavored e-liquids exacerbates endothelial cell dysfunction, study finds

There has been a rapid rise in e-cigarette use, but its health effects have not been well-studied and their effect on vascular health remains unknown.