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Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

Researchers at Queen Mary University of London and University College London have shown that using stem cells derived from patients could help find new treatments for a group of congenital muscular dystrophies.

30 Sep 2019

Functional three-organoid stem cell system could lead to unprecedented advances for precision medicine

Using iPS cells, a Japanese research group has successfully grown a connected set of organs at the same time, including a liver and a pancreas connected by a bile duct.

27 Sep 2019

New needle-free 'exosome' treatment to reduce wrinkles in UV-exposed mice

In the quest for a more youthful appearance, many people slather ointments on their skin or undergo injections of dermal fillers. But topical treatments often aren't very effective because they don't penetrate deep within the skin, whereas the results from injections typically last for only a few months and can be painful.

25 Sep 2019

Gene regulators work together to raise individual's risk of schizophrenia

Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia.

23 Sep 2019

Natural antioxidant in green tea can help eliminate antibiotic-resistant bacteria

Scientists at the University of Surrey have discovered that a natural antioxidant commonly found in green tea can help eliminate antibiotic-resistant bacteria.

23 Sep 2019

No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

Forbidden fruit: Scientists venture into “embryoid” manufacturing

After working on stem cells for several years, scientists have now announced that they have found a way to synthesize structures that look like very primitive human embryos. While some hailed the discovery, others questioned the ethical basis of manufacturing synthetic humans.

12 Sep 2019

Too much vitamin D may reduce bone density, say scientists

Excessive supplementation with vitamin D can cause bone loss and bone weakening, according to a new study.

6 Sep 2019

Neurobiological pathophysiology of schizophrenia differs based on gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study.

4 Sep 2019

Study reshapes the understanding of telomerase's function in normal cells

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase.

3 Sep 2019

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Brain organoids — also called mini-brains — are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments.

30 Aug 2019

Psychopathy associated with robust alterations in expression of genes, study shows

The expression of many genes that have previously been associated with autism is abnormal also in violent psychopathy, a new study shows.

30 Aug 2019

“Mini Brains” in the lab show electrical activity similar to a preemie’s brain

Researchers have developed successfully mini brains in the labs which are essentially a cluster of brain cells perfused in fluids. These brain tissues are now showing electrical activity akin to real brain, explain the researchers and this is a path-breaking development in brain research.

29 Aug 2019

New study reveals mechanism of ultraviolet-induced skin breakdown

The sunscreen industry has been plugging the use of various sun-protective creams for decades, ever since researchers found that certain skin cancers, including malignant melanoma, were due to sunlight-induced skin damage.

22 Aug 2019

MSD collaborates with Francis Crick to find causes of motor neurone disease

Scientists at global biopharmaceutical company MSD and the Francis Crick Institute have started a unique new collaboration to understand the causes of Motor Neurone Disease and identify potential targets for future treatments, co-funded by MSD and the UK Medical Research Council.

21 Aug 2019

Study identifies key epigenetic regulator that controls skin cell turnover

The outer layer of the skin completely replaces itself every two to four weeks, but when this process is blocked, cancer can grow.

21 Aug 2019

Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Pitt researchers first to grow genetically modified miniature human livers in the lab

Researchers at the University of Pittsburgh School of Medicine are the first to grow genetically modified miniature human livers in the laboratory, to emulate human liver disease progression and test therapeutics.

7 Aug 2019

Sheffield academic receives funding to protect brain cells affected by Parkinson's

A Sheffield academic has been awarded £100,000 of funding by the Virtual Biotech Programme - the drug development arm of charity Parkinson's UK - to develop a new treatment that could protect brain cells affected by Parkinson's disease, potentially slowing, or stopping its progression for the first time.

6 Aug 2019