G Protein News and Research

RSS

Molecular evolution in separate species predicts convergence of toxin resistance

Researchers at LSTM have shown that under certain circumstances evolution can be highly predictable, especially in terms of how creatures become resistant to dangerous toxins.

8 Sep 2015

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

8 Sep 2015

Researchers identify machines critical for development and survival of species

In one of the largest and most detailed studies of animal molecular biology ever undertaken, researchers at The University of Texas at Austin and the University of Toronto discovered the assembly instructions for nearly 1,000 protein complexes shared by most kinds of animals, revealing their deep evolutionary relationships. Those instructions offer a powerful new tool for studying the causes of diseases such as Alzheimer's, Parkinson's and cancer.

7 Sep 2015

Desmoplasmic melanoma may possess unprecedented burden of gene mutations, say UCSF scientists

A rare, deadly form of skin cancer known as desmoplasmic melanoma (DM) may possess the highest burden of gene mutations of any cancer, suggesting that immunotherapy may be a promising approach for treatment, according to an international team led by UC San Francisco scientists. One of these mutations, never before observed in any cancer, may shield nascent DM tumors from destruction by the immune system and allow further mutations to develop.

7 Sep 2015

Antibiotic resistance awareness: an interview with Professor Colin Garner

The threat of antibiotic resistance is very real. It is estimated that 700,000 people die each from resistant infections. In Europe the figure is 25,000 deaths and a similar number in the USA.

7 Sep 2015

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

A research group at Umeå University in Sweden, together with researchers in Munich, have identified two enzymes from the pathogenic Legionella bacteria that are very useful in chemically modifying proteins to be used in medical drugs. The result of the study is presented in the chemical journal Angewandte Chemie International Edition.

7 Sep 2015

RAB35 protein plays role in oncogenic process

A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth-control pathway.

4 Sep 2015

Endothelin system offers potential therapeutic target for ALS

Amyotrophic lateral sclerosis (ALS) is a disorder in which cells of the nervous system die, leading to muscle weakness that impacts breathing, movement and other physical functions.

4 Sep 2015

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Some treatments for type 2 diabetes make the body more sensitive to insulin, the hormone that lowers blood sugar. But new research at Washington University School of Medicine in St. Louis suggests a different strategy: slowing the production of glucose in the liver.

4 Sep 2015

Researchers one step closer to developing asthma vaccine

Researchers at VIB (a leading life sciences institute in Flanders, Belgium) and Ghent University have successfully established a causal relationship between exposure to so-called farm dust and protection against asthma and allergies.

4 Sep 2015

New treatments under development for adults with coeliac disease may also benefit children

A new study has revealed childhood coeliac disease mirrors the condition in adults, increasing the possibility a coeliac disease therapy that could enable patients to eat gluten again will work in children.

4 Sep 2015

Mel18 protein regulates development of heart muscle

It is arguably the hardest working muscle in our body and without its incessant, regular beating our organs would be starved of life-giving nutrients.

4 Sep 2015

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition's complications, including kidney failure, heart disease, and blindness. Most diabetes medications aim to maintain normal blood sugar (glucose) levels and prevent high blood sugar by controlling insulin.

3 Sep 2015

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research.

3 Sep 2015

Scientists identify new mechanism for severe early infant epilepsy

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory.

3 Sep 2015

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2015

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Sep 2015

Researchers create method to watch activity of motor neurons in real time

When you're taking a walk around the block, your body is mostly on autopilot--you don't have to consciously think about alternating which leg you step with or which muscles it takes to lift a foot and put it back down. That's thanks to a set of cells in your spinal cord that help translate messages between your brain and your motor neurons, which control muscles.

3 Sep 2015

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct adverse health effect on the liver and causes liver fibrosis, an illness associated with metabolic disease and liver cancer.

3 Sep 2015

TMIGD1 protein could be a novel target for restoring kidney function from kidney disease

A new discovery by Boston University School of Medicine (BUSM) researchers may change how kidney disease is treated in the future.

3 Sep 2015

G Protein News and Research

Molecular evolution in separate species predicts convergence of toxin resistance

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Researchers identify machines critical for development and survival of species

Desmoplasmic melanoma may possess unprecedented burden of gene mutations, say UCSF scientists

Antibiotic resistance awareness: an interview with Professor Colin Garner

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

RAB35 protein plays role in oncogenic process

Endothelin system offers potential therapeutic target for ALS

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Researchers one step closer to developing asthma vaccine

New treatments under development for adults with coeliac disease may also benefit children

Mel18 protein regulates development of heart muscle

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Scientists identify new mechanism for severe early infant epilepsy

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Researchers create method to watch activity of motor neurons in real time

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

TMIGD1 protein could be a novel target for restoring kidney function from kidney disease

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News