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What is the impact of SARS-CoV-2 variant booster vaccinations?

Researchers conducted preliminary assessments of a booster vaccination with the SARS-CoV-2 variant vaccines.

19 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application to the European Medicines Agency for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 19 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.

18 Jul 2022

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Researchers showed that the SARS-CoV-2 nucleocapsid (N) and spike (S) proteins did not activate γδ T cells and dendritic cells (DCs).

18 Jul 2022

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

A new study showed that 7DW8-5, an immunostimulatory glycolipid impeded three respiratory viral infections, including SARS-CoV-2, in vivo.

18 Jul 2022

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers screened bacterial mucosal vaccine vectors from 2015 to the present to identify a promising candidate to present SARS-CoV-2 spike protein or its fragments.

18 Jul 2022

The characteristics of circulating T follicular helper cells in COVID-19 patients across mild to severe disease

Researchers found that late generation of functional SARS-CoV-2-selective circulating T follicular helper cells correlated with severe illness.

18 Jul 2022

Cytokine-based cancer immunotherapy: current progress and future prospects

In this interview, News-Medical talks to Dr. Shuang Zhou about cytokine-base cancer immunotherapy, the current state of the field, and future prospects.

From Sino Biological Inc. 18 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Study results encourage SARS-CoV-2–infected mothers breastfeed to protect infants from COVID

A new study examines the strength of protection against COVID-19 using antibody concentrations at birth and after six months in mothers and children.

17 Jul 2022

The potential of circular RNA COVID-19 vaccines

A new MedComm study describes the potential use of circular ribonucleic acid COVID-19 vaccines.

17 Jul 2022

Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets

Scientists have published a new review focusing on the relationship between PD and gut microbiota.

15 Jul 2022

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

A recent research paper posted to the medRxiv* preprint server illustrated anti-inflammatory and hypo-metabolic fingerprints in long coronavirus disease (COVID) syndrome (LCS) using pan-omics plasma assessments.

15 Jul 2022

Phase I clinical trial of new blocking antibody therapy shows promising results for the treatment of advanced medulloblastoma

Effective and safe treatments are needed for medulloblastoma - the most common type of cancerous brain tumor in children - especially for patients whose cancer has spread to the spinal cord.

14 Jul 2022

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

Neutralizing mAbs identified in the current study sheds light on ACE2-triggered conformational change that restricts the immunogenicity of the highly conserved FP region.

14 Jul 2022

The interaction between SARS-CoV-2 and influenza A during coinfection

Researchers assessed the host response to influenza A and COVID-19 during coinfection.

14 Jul 2022

MINAR2 gene mutations cause progressive hearing loss

Researchers at the John T. Macdonald Department of Human Genetics and the John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families. The gene variation mostly affects the inner ear hair cells, which are critical to hearing.

14 Jul 2022

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Vaccines may need to dig a little deeper to stop SARS-CoV-2. Rice University researchers are providing a new shovel.

14 Jul 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Receptor News and Research

What is the impact of SARS-CoV-2 variant booster vaccinations?

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

The characteristics of circulating T follicular helper cells in COVID-19 patients across mild to severe disease

Cytokine-based cancer immunotherapy: current progress and future prospects

Novel nanoligomer approach to treat severe COVID-19

Study results encourage SARS-CoV-2–infected mothers breastfeed to protect infants from COVID

The potential of circular RNA COVID-19 vaccines

Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

Phase I clinical trial of new blocking antibody therapy shows promising results for the treatment of advanced medulloblastoma

Researchers identify fusion peptide-specific monoclonal antibodies with broad neutralizing activity

The interaction between SARS-CoV-2 and influenza A during coinfection

MINAR2 gene mutations cause progressive hearing loss

SARS-Arena reveals conserved parts of viral proteins that cause COVID-19

Lipids in breastmilk may protect against metabolic disease later in life

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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