Protein C News and Research

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Discovery of a new anticoagulant

The discovery of a new anticoagulant with promising therapeutic value is reported on the 20th of February issue of the journal PLoS ONE1.

20 Feb 2008

New key finding in neurodevelopment

A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus.

20 Feb 2008

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors

Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers - neuroblastoma and peripheral nerve sheath tumors - without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus, according to study results published in the February 15 Cancer Research.

18 Feb 2008

Transplanted cells can cure hemophilia

Scientists at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that transplanted cells can cure hemophilia A (the most common form of the disease) in an animal model.

18 Feb 2008

Stanford researchers make first direct observation of 3-D molecule folding in real time

All the crucial proteins in our bodies must fold into complex shapes to do their jobs.

18 Feb 2008

Researchers find protein targets for potential treatment of multiple sclerosis

Multiple sclerosis is not a single condition, but an ebbing and flowing of stages affecting the body ' s central nervous system.

18 Feb 2008

Discovery of antibody that neutralizes two viruses classified as henipaviruses

In laboratory experiments, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues supported by the NIH National Institute of Allergy and Infectious Disease (NIAID), have discovered an antibody that neutralizes two viruses classified as henipaviruses.

18 Feb 2008

Role gound for glaucoma gene and a signaling pathway

Researchers have found that a gene and a related signaling pathway play a role in the development of glaucoma, which is a common cause of visual impairment and blindness worldwide.

18 Feb 2008

Strength of spider silk lies in geometric configuration of structural proteins

Researchers in Civil and Environmental Engineering at MIT reveal that the strength of a biological material like spider silk lies in the specific geometric configuration of structural proteins, which have small clusters of weak hydrogen bonds that work cooperatively to resist force and dissipate energy.

17 Feb 2008

Protein found in the saliva of deer ticks prevents the HIV-1 virus from attaching to the surface of T cells

The HIV-1 virus cripples the human immune system by targeting white blood cells called T cells that form the body's first line of defense in fighting infections.

17 Feb 2008

Scorpion venom may hold key to controlling cystic fibrosis

Researchers have discovered a peptide in scorpion venom that may hold the key to understanding and controlling cystic fibrosis and other secretory diseases.

17 Feb 2008

Oncoproteins double-team and destroy vital tumor-suppressor

Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Feb. 10 issue of Nature Cell Biology.

17 Feb 2008

Discovery of new cataract gene

The international team of researchers was able to identify the location and defect in the coding region of the gene through analysis of genetic material (DNA) from members of a large Swiss family, the majority of whom suffered from autosomal dominant juvenile cataract.

17 Feb 2008

Mesothelin appears to play important role in promoting pancreatic cancer growth - clues to new treatments

New understanding of a protein that spurs the growth of pancreatic cancer could lead to a new vaccine against the deadly disease, said researchers at Baylor College of Medicine in Houston in a report appearing in the current edition of the journal Molecular Cancer Therapeutics.

17 Feb 2008