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PGDx launches LungSelect product to identify genetic alterations in the plasma of NSCLC patients

Personal Genome Diagnostics, Inc., a provider of advanced cancer genome analysis and testing services, today announced the launch of its LungSelect product that identifies the most common, clinically actionable genetic alterations in the plasma of non-small cell lung cancer (NSCLC) patients.

11 Jun 2015

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Contrary to current medical dogma, researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors.

11 Jun 2015

Study reveals new information about role of abdominal fat in teens with CAH

Researchers at Children's Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).

11 Jun 2015

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

This week, Lancet Oncology reports results of a 1,093-person phase III clinical trial of the drug necitumumab (IMC-11F8) combined with chemotherapies gemcitabine and cisplatin against stage IV squamous non-small cell lung cancer. With addition of necitumumab, median overall survival was 11.5 months compared with median survival of 9.9 months with the two chemotherapies alone.

11 Jun 2015

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently mutated in a common form of adult leukemia and is likely necessary to bring about the full-blown disease.

11 Jun 2015

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Specialized brain proteins that are involved in the removal of damaged nerve cell materials may be detected in the blood of people who were diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease.

11 Jun 2015

Scientists and clinicians from across the UK come together to address treatment of brain tumors

In an exciting step forward to finding a cure for brain tumours, which kill more children and adults under the age of 40 than any other cancer, the national charity Brain Tumour Research brought together a group of leading brain tumour scientists and clinicians to help accelerate vital research into this devastating disease.

11 Jun 2015

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

A Case Comprehensive Cancer Center brain surgeon and neurosurgery professor is among the primary authors of a new approach to classifying tumors that could lead to significant improvements in their diagnosis and treatment. The research and recommendations appear online June 10 in The New England Journal of Medicine.

11 Jun 2015

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

After decades of effort, scientists are finally figuring out how insects develop resistance to environmentally friendly farming practices - such as crop rotation - that are designed to kill them. The researchers say their insights will help develop more sustainable agricultural practices.

11 Jun 2015

Findings point to new therapy against prostate and other cancers

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a drug candidate with anticancer potential can be activated by one of the body's natural responses to cellular stress. Once activated, the agent can kill prostate cancer cells.

11 Jun 2015

Two fragile X proteins play crucial role in proper development of neurons

Fragile X syndrome is the most common inherited intellectual disability and the greatest single genetic contributor to autism. Unlocking the mechanisms behind fragile X could make important revelations about the brain.

11 Jun 2015

New study links sleep deprivation to etiology of biological aging in older adults

A new study suggests that one night of partial sleep deprivation promotes biological aging in older adults. Results show that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.

11 Jun 2015

Early intervention improves outcomes for young children with ASD

A recent study published in the July 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry demonstrates that early intervention, beginning between 18 and 30 months of age improves outcomes for children with autism spectrum disorder (ASD) at age 6.

11 Jun 2015

Stage IIIB NSCLC patients may benefit from surgical resection in combination with chemo or radiation therapy

Patients diagnosed with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection (removal of all or part of the lung) in combination with chemotherapy and radiation therapy, according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

11 Jun 2015

UC San Diego researchers launch clinical trial to evaluate safety, efficacy of suramin drug for autism

Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety and efficacy of an unprecedented drug therapy for autism.

11 Jun 2015

Study on how maternal proteins help regulate initial cell divisions during early development

Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.

10 Jun 2015

Simple process for obtaining induced pluripotent stem cells without use of reagents

For their ability to differentiate into other cell types, the embryonic stem cells hold a large potential in the medical industry. Their use, however, poses ethical questions due to the fact that in order to obtain them, it is necessary to destroy the embryo. For this reason, medical researches use the so-called induced pluripotent stem cells (iPSC). In fact, it is possible to reprogram adult cells that can be obtained by simply drawing blood and making them "regress" to a similar state to that of embryonic stem cells.

10 Jun 2015

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Amgen today announced that the Company will discuss the data supporting the Repatha (evolocumab) Biologics License Application (BLA) for the treatment of high cholesterol with the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC).

10 Jun 2015

Switching from Remicade to Inflectra benefits patients with rheumatic diseases

Hospira, Inc., a global leader in biosimilars, today announced the results of an independent clinical study, showing patients with rheumatic diseases experienced comparable clinical effectiveness and safety after switching from Remicade™ to Inflectra.

10 Jun 2015

Study reveals how immune cells are programmed to repair or protect the body

An unexpected finding by an international team of scientists based at The University of Manchester and National Institutes of Health in America has shed new light on how immune cells are programmed to either repair or protect the body.

10 Jun 2015

Cell News and Research

PGDx launches LungSelect product to identify genetic alterations in the plasma of NSCLC patients

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Study reveals new information about role of abdominal fat in teens with CAH

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Scientists and clinicians from across the UK come together to address treatment of brain tumors

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

Findings point to new therapy against prostate and other cancers

Two fragile X proteins play crucial role in proper development of neurons

New study links sleep deprivation to etiology of biological aging in older adults

Early intervention improves outcomes for young children with ASD

Stage IIIB NSCLC patients may benefit from surgical resection in combination with chemo or radiation therapy

UC San Diego researchers launch clinical trial to evaluate safety, efficacy of suramin drug for autism

Study on how maternal proteins help regulate initial cell divisions during early development

Simple process for obtaining induced pluripotent stem cells without use of reagents

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Switching from Remicade to Inflectra benefits patients with rheumatic diseases

Study reveals how immune cells are programmed to repair or protect the body

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