Antigen News and Research

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Study could offer new ways to enhance cancer immunotherapy

When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties.

4 Jul 2016

New strategy treats fatal autoimmune disease without outward off-target effects

In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

4 Jul 2016

Researchers design E. coli-based transport capsule to help fight pneumococcal disease

Most people recoil at the thought of ingesting E. coli. But what if the headline-grabbing bacteria could be used to fight disease?

4 Jul 2016

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Though a variety of immunotherapy-based strategies are being used against cancer, they are often hindered by the inability of the immune response to enter the immunosuppressive tumor microenvironment and to effectively mount a response to cancer cells.

1 Jul 2016

Researchers test experimental Zika virus vaccine in mice

An experimental vaccine against Zika virus developed by Brazilian and US researchers has been tested successfully in trials with mice.

30 Jun 2016

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0, to create new viral vectors to find quicker and better treatments for an array of diseases. James M. Wilson, MD, PhD, a professor of Medicine and director of the Orphan Disease Center, will lead an interdisciplinary team of over 30 scientists to create this new technology platform with support provided by the University of Pennsylvania Health System.

30 Jun 2016

TSRI scientists develop new strategy to design potential HIV vaccine candidates

Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus's tell-tale structure. That's part of the basic approach behind efforts at The Scripps Research Institute to design an AIDS vaccine.

29 Jun 2016

Home test using paper strips could help detect cancer, malaria

What if testing yourself for cancer or other diseases were as easy as testing your blood sugar or taking a home pregnancy test? In a few years, it might be.

29 Jun 2016

Scientists create protein signatures for accurate diagnosis of prostate cancer

Researchers at the Ontario Institute for Cancer Research and University Health Network in Toronto, along with researchers at the Eastern Virginia Medical School, have created protein signatures that accurately diagnose prostate cancer and can distinguish between patients with aggressive versus non-aggressive disease using a simple urine sample.

29 Jun 2016

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study published online this week in the journal VACCINE.

27 Jun 2016

NYU Lutheran helps patients fight prostate cancer with latest diagnostic and robotic surgery technology

Leading NYU Lutheran's fight is Marc Bjurlin, DO, the hospital's newly appointed director of urologic oncology and clinical assistant professor of urology at NYU School of Medicine.

27 Jun 2016

Scientists discover link between two genes involved in PD and autoimmune diseases

A study publish in the journal CELL indicates that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

27 Jun 2016

'Simple' model predicts PegIFN response in chronic HBV

Chinese researchers have developed a scoring system based on hepatitis B virus-related clinical parameters to predict response to pegylated-interferon in chronic HBV patients.

23 Jun 2016

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

In patients with chronic hepatitis B virus infection who have been newly diagnosed with cirrhosis, the risk of hepatocellular carcinoma development can be ascertained using several clinical and molecular factors, study findings indicate.

23 Jun 2016

Maternal HBsAg can serve as HBV vertical transmission marker

Two studies have independently identified quantitative hepatitis B surface antigen as a marker to identify pregnant women with chronic hepatitis B virus infection whose infants are at high-risk of infection despite immunoprophylaxis.

23 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Researchers aim to improve medical treatment for people with insect venom allergy

A team of researchers has elucidated individual profiles of allergy reactivity in patients that are not protected after treatment with immunotherapy. The aim is to improve medical treatment of people who are allergic to insect stings.

21 Jun 2016

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

When the body is fighting an invading pathogen, white blood cells--including T cells--must respond. Now, Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated.

16 Jun 2016

New immunotherapy treatment could change the way cancer is treated

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, a new approach in cancer treatment that has a promising outlook.

16 Jun 2016

Portable biosensor can detect and amplify signal of harmful bacteria

Washington State University researchers have developed a portable biosensor that makes it easier to detect harmful bacteria.

15 Jun 2016

Antigen News and Research

Study could offer new ways to enhance cancer immunotherapy

New strategy treats fatal autoimmune disease without outward off-target effects

Researchers design E. coli-based transport capsule to help fight pneumococcal disease

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Researchers test experimental Zika virus vaccine in mice

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

TSRI scientists develop new strategy to design potential HIV vaccine candidates

Home test using paper strips could help detect cancer, malaria

Scientists create protein signatures for accurate diagnosis of prostate cancer

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

NYU Lutheran helps patients fight prostate cancer with latest diagnostic and robotic surgery technology

Scientists discover link between two genes involved in PD and autoimmune diseases

'Simple' model predicts PegIFN response in chronic HBV

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

Maternal HBsAg can serve as HBV vertical transmission marker

New CAR-based therapy using combined cancer target could be effective for solid tumors

Researchers aim to improve medical treatment for people with insect venom allergy

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

New immunotherapy treatment could change the way cancer is treated

Portable biosensor can detect and amplify signal of harmful bacteria

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