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Chemical changes in genetic material regulate activity of many genes

Chemical changes in the genetic material, known as epigenetic modifications, regulate the activity of many genes. Thus, attachment of methyl groups to DNA often inactivates important cellular growth brakes. Therefore, this process called methylation is believed to be a major cause of uncontrolled division of cancer cells. Specific enzymes, the DNA methyltransferases, are responsible for methylation.

7 May 2010

Creator of California Tay-Sachs Disease Prevention Program among the honorees

A mere 40 years ago, parents didn't know they were carriers of the Tay-Sachs disease until after they'd given birth to a child with this fatal genetic disorder.

7 May 2010

Icagen reports revenues of $1.5M, net loss of $3.2M for first-quarter 2010

Icagen, Inc. reported today its financial results and operational highlights for the first quarter ended March 31, 2010. For the first quarter of 2010, the Company reported revenues of $1.5 million and a net loss of $3.2 million. As of March 31, 2010, the Company's cash and cash equivalents totaled $14.3 million.

7 May 2010

Cytori Therapeutics to initiate European medical device approval study for Celution System

The first clinical trial of adipose (fat) tissue-derived stem and regenerative cells for the treatment of heart attacks showed a substantial reduction in the size of injury to the heart, an improvement in the amount of blood supply to the heart muscle, and a corresponding functional improvement in the amount of blood the heart can pump.

7 May 2010

NPWH launches ETIQ campaign to improve access to information about menopause, estrogen therapy

The National Association of Nurse Practitioners in Women's Health announced the launch of Estrogen Therapy I.Q. a campaign devoted to improving access to credible information about menopause and advances in estrogen therapy.

7 May 2010

Comprehensive education program in respiratory therapy

Teleflex Medical has announced the introduction of a comprehensive education program in respiratory therapy, designed to provide an in-depth curriculum focused on maximizing humidification and minimizing challenges through the therapeutic levels outlined in the Respiratory Pyramid of Care. The courses are accredited by the American Association for Respiratory Care.

7 May 2010

DUSA Pharmaceuticals receives notice of allowance for patent covering blue light technology

DUSA Pharmaceuticals, Inc.®, a dermatology company that is developing and marketing Levulan® Photodynamic Therapy (PDT), today announced that the United States Patent and Trademark Office has issued a notice of allowance for a key patent related to its proprietary PDT light source, the BLU-U®, Blue Light Photodynamic Therapy Illuminator.

7 May 2010

Researchers analyze relationship between extent of resection and outcome in patients with glioblastoma

Gliomas arise from the supporting cells of the brain, called the glia. These cells are subdivided into astrocytes, ependymal cells and oligodendroglial cells (or oligos). These tumors are graded from the lowest grade 1 to highest grade 4, with glioblastoma multiforme being the highest grade and deadliest type of glioma.

7 May 2010

Minimally invasive scopes to detect cancer

Just as cameras and televisions have been reinvented in the last decade with improved optics, sharpness and brightness, so have the tiny imaging scopes that physicians use to peer into the body's nooks and crannies -- its organs and digestive system.

7 May 2010

Kaposi's Sarcoma-associated herpesvirus replicates, spreads by hijacking PYM cellular protein

Research from the University of Leeds has identified how the virus which causes Kaposi's Sarcoma replicates and spreads - opening a door to a possible new treatment for the disease.

7 May 2010

Ohio scientists demonstrate existence of effective technology for nationwide newborn screening of SMA

Scientists in Ohio studying Spinal Muscular Atrophy (SMA) have concluded that the technology now exists to carry out nationwide screening of newborn children and pregnant mothers. The study, published in the American Journal of Medical Genetics, reveals that effective screening may allow parents to find proactive treatments before the symptoms become irreversible.

7 May 2010

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Chronic pain severely limits patients' quality of life and is among the cost drivers in U.S. health care. Patients can suffer pain without an apparent cause and often fail to respond to available treatments. Mayo Clinic researchers and collaborators now report that chronic pain may be caused by the inadvertent reprogramming of more than 2,000 genes in the peripheral nervous system. The research findings appear in the current issue of the journal Genome Research.

7 May 2010

Movements of satellite cells could help patients with muscular dystrophy: MU researchers

When muscle tissue experiences trauma or disease, such as muscular dystrophy, stem cells in the muscle known as "satellite cells" respond to repair and regenerate the muscle. These cells are particularly important in neuromuscular diseases, such as muscular dystrophy, which affect muscle stability and repair.

7 May 2010

Advances in combination adult stem cell treatment for acute myocardial infarction presented at SCAI

This week, TCA Cellular Therapy's Medical Director Gabriel Lasala, M.D. presents advances in a proprietary combination adult stem cell treatment for acute myocardial infarction at the Society for Cardiovascular Angiography and Interventions (SCAI) scientific conference in San Diego.

7 May 2010

Progestins increase chances of cancer metastasizing: Study

After menopause, 6 to 10 million women take hormone therapies, which are often a combination of estrogen and progestin, to replace hormones lost from inactive ovaries. Progestin is a hormone that is used to counteract the potentially negative effects of estrogen therapy on the uterus. In studies sponsored by the National Institutes of Health, evidence has been found that estrogen and progestin in hormone therapies increase the risk of breast cancer in post-menopausal women.

7 May 2010

Sleep disturbance may result in negative consequences among residents of ALFs: Study

In a study of residents of Assisted Living Facilities in Los Angeles showed that 65% had clinically significant sleeping problems and that poor sleep was associated with declining quality of life and increased depression over a six month follow-up period. This study is published today in the Journal of the American Geriatrics Society.

7 May 2010

Study reveals benefits of X-ray guided steroid injections for treatment of hamstring tendonitis

Fluoroscopic (X-ray) guided steroid injections offer a safe and effective alternative to the conventional treatment of hamstring tendonitis, according to a study to be presented at the ARRS 2010 Annual Meeting in San Diego, CA. Conventional treatment includes rest, anti-inflammatory drugs, and physical therapy.

7 May 2010

THI at St. Luke's reveals new insights on how adult stem cells repair damaged hearts following heart attack

Physician scientists at the Texas Heart Institute at St. Luke's Episcopal Hospital (THI at St. Luke's) are publishing research this week that reveals new insights into how a particular set of human adult stem cells helps repair damaged hearts following a heart attack in laboratory mice.

7 May 2010

Medtronic initiates U.S. clinical trial of RestoreSensor neurostimulator in chronic pain patients

Medtronic, Inc. today announced the initiation of a prospective, multi-center, randomized U.S. clinical trial for the RestoreSensorTM neurostimulator that adapts therapy to the changing needs of chronic pain patients by responding automatically to changes in body position and activity in an upright position.

7 May 2010

Sleep problems can increase depression and reduce quality of life in older people

In a study of residents of Assisted Living Facilities (ALFs) in Los Angeles showed that 65% had clinically significant sleeping problems and that poor sleep was associated with declining quality of life and increased depression over a six month follow-up period. This study is published today in the Journal of the American Geriatrics Society.

7 May 2010

Therapy News and Research

Chemical changes in genetic material regulate activity of many genes

Creator of California Tay-Sachs Disease Prevention Program among the honorees

Icagen reports revenues of $1.5M, net loss of $3.2M for first-quarter 2010

Cytori Therapeutics to initiate European medical device approval study for Celution System

NPWH launches ETIQ campaign to improve access to information about menopause, estrogen therapy

Comprehensive education program in respiratory therapy

DUSA Pharmaceuticals receives notice of allowance for patent covering blue light technology

Researchers analyze relationship between extent of resection and outcome in patients with glioblastoma

Minimally invasive scopes to detect cancer

Kaposi's Sarcoma-associated herpesvirus replicates, spreads by hijacking PYM cellular protein

Ohio scientists demonstrate existence of effective technology for nationwide newborn screening of SMA

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Movements of satellite cells could help patients with muscular dystrophy: MU researchers

Advances in combination adult stem cell treatment for acute myocardial infarction presented at SCAI

Progestins increase chances of cancer metastasizing: Study

Sleep disturbance may result in negative consequences among residents of ALFs: Study

Study reveals benefits of X-ray guided steroid injections for treatment of hamstring tendonitis

THI at St. Luke's reveals new insights on how adult stem cells repair damaged hearts following heart attack

Medtronic initiates U.S. clinical trial of RestoreSensor neurostimulator in chronic pain patients

Sleep problems can increase depression and reduce quality of life in older people

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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