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$Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL$

Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval of ADCETRIS (brentuximab vedotin) from the Japanese Ministry of Health, Labour and Welfare for the treatment of patients with CD30-positive relapsed or refractory Hodgkin lymphoma and anaplastic large cell lymphoma.

18 Jan 2014

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Scientists have made an important advance in understanding how a subset of bacterial cells escape being killed by many antibiotics.

10 Jan 2014

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

[The] problem with the Affordable Care Act isn't the insurance industry. In fact, the main benefits of nationalized health care can be achieved in systems with hundreds, even thousands, of for-profit insurers. ...

10 Jan 2014

GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved Mekinist® (trametinib) for use in combination with Tafinlar® (dabrafenib) for the treatment of patients with unresectable melanoma (melanoma that cannot be removed by surgery) or metastatic melanoma (melanoma which has spread to other parts of the body) with BRAF V600E or V600K mutations.

9 Jan 2014

Working out while sick can actually do more harm than good, says professor

With the flu and cold season in full swing, kinesiology professor Karin Richards, at University of the Sciences in Philadelphia, said many people tend to ignore their symptoms to keep on track with their fitness resolutions for the New Year.

8 Jan 2014

Viewpoints: Slowing health costs; possibility of Medicaid deal in virginia; a new name for brain death

For decades a common refrain was that the rapid rise in health spending hurt the competitiveness of American businesses and ate into workers' take-home pay. Businesses and politicians from both sides of the aisle agreed that something had to be done to slow the growth of health-care costs.

8 Jan 2014

Low gut microbial diversity in infants' intestines can increase risk for asthma

Low gut microbial diversity in the intestines of infants can increase the risk for asthma development. These are the findings of the age 7 follow-up in a multi-year study led by researchers at Linköping University in Sweden.

7 Jan 2014

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Commission has granted approval for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas, or metastatic pancreatic cancer.

7 Jan 2014

Influenza and pneumococcal vaccines together appear to increase risk of fever in children

Giving young children the influenza and pneumococcal vaccines together appears to increase their risk of fever, according to a study led by researchers from Columbia University Medical Center (CUMC) and the Centers for Disease Control and Prevention (CDC). However, the fever was brief, and medical care was sought for few children, supporting the routine immunization schedule for these vaccines, including the recommendation to administer them simultaneously.

6 Jan 2014

FDA extends PDUFA Priority Review action date for UC indication of Takeda's vedolizumab

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., today announced that the United States Food & Drug Administration has extended the Prescription Drug User Fee Act Priority Review action date for the ulcerative colitis indication of Takeda's investigational biologic, vedolizumab.

24 Dec 2013

Researchers develop new vaccine that protects against lethal pneumonia caused by staph bacteria

University of Iowa researchers have developed a new vaccine that protects against lethal pneumonia caused by Staphylococcus aureus (staph) bacteria, including drug-resistant strains like MRSA.

23 Dec 2013

Immunologists discover risk factor responsible for infectious mononucleosis in young people

More than 90 percent of all adults are carriers of the oncogenic Epstein-Barr Virus. Primary infection with this herpes virus as a young child is generally not linked to any symptoms, and usually offers life-long protection from its cancer-causing effect. However, for people who do not become infected with the virus until adolescence, the infection often leads to infectious mononucleosis (commonly known as glandular fever). Our immune systems can generally fend off this disease after a period of between one and several months. However, there is an increased risk of developing Hodgkin lymphoma at a later stage, a cancerous tumor of the lymphatic system.

20 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

People with intermittent explosive disorder — a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts — have elevated levels of two markers of systemic inflammation in their blood, according to a study involving nearly 200 subjects.

19 Dec 2013

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Testing the efficacy of vaccines in clinical trials takes years, even decades. Yet challenging infections like HIV, malaria and dengue are striking today. To speed up vaccine testing, scientists at the Emory Vaccine Center have established a goal of creating a "vaccine gene chip."

17 Dec 2013

Scientists find vaccine that blocks invasion of blood cell by Malaria parasite

Scientists from Singapore's Nanyang Technological University (NTU) have discovered a key process during the invasion of the blood cell by the Malaria parasite, and more importantly, found a way to block this invasion.

16 Dec 2013

Janssen receives complete response letter for canagliflozin/metformin FDC therapy for type 2 diabetes

Janssen Research & Development, LLC (Janssen) today announced it has received from the U.S. Food and Drug Administration (FDA) a complete response letter regarding its New Drug Application (NDA) for a fixed-dose combination (FDC) of canagliflozin and immediate-release metformin to treat adults with type 2 diabetes.

16 Dec 2013

NTU researchers find way to block invasion of Malaria parasite in blood cells

Scientists from Singapore's Nanyang Technological University have discovered a key process during the invasion of the blood cell by the Malaria parasite, and more importantly, found a way to block this invasion.

16 Dec 2013

Pregnant women, infants should avoid unpasteurized milk products, urge pediatricians

Pregnant women, infants and young children should avoid raw or unpasteurized milk and milk products and only consume pasteurized products, according to a new policy statement from the American Academy of Pediatrics.

16 Dec 2013

New approach for combating seasonal flu

Reducing glucose metabolism dials down influenza viral infection in laboratory cell cultures, providing an entirely new approach for combating seasonal flu, according to research that will be presented on Sunday, Dec. 15, at the American Society for Cell Biology annual meeting in New Orleans.

15 Dec 2013

Fever News and Research

Japanese MHLW approves ADCETRIS for relapsed or refractory CD30-positive HL and ALCL

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

Working out while sick can actually do more harm than good, says professor

Viewpoints: Slowing health costs; possibility of Medicaid deal in virginia; a new name for brain death

Low gut microbial diversity in infants' intestines can increase risk for asthma

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

Influenza and pneumococcal vaccines together appear to increase risk of fever in children

FDA extends PDUFA Priority Review action date for UC indication of Takeda's vedolizumab

Researchers develop new vaccine that protects against lethal pneumonia caused by staph bacteria

Immunologists discover risk factor responsible for infectious mononucleosis in young people

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Scientists find vaccine that blocks invasion of blood cell by Malaria parasite

Janssen receives complete response letter for canagliflozin/metformin FDC therapy for type 2 diabetes

NTU researchers find way to block invasion of Malaria parasite in blood cells

Pregnant women, infants should avoid unpasteurized milk products, urge pediatricians

New approach for combating seasonal flu

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