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Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Resverlogix Corp. is pleased to announce that Dr. Norman Wong, chief scientific officer of Resverlogix Corp. presented new data at the European Society of Cardiology (ESC) Congress 2015 in a poster presentation titled: "RVX-208, an orally active BET inhibitor, lowers CVD risk by activities beyond raising ApoA-I/HDL."

31 Aug 2015

Scientists identify new protein that regulates severity of tissue damage caused by RA

Scientists have identified a new protein (C5orf30) which regulates the severity of tissue damage caused by rheumatoid arthritis (RA), an autoimmune disease that causes inflammation, pain, stiffness and damage to the joints of the feet, hips, knees, and hands.

31 Aug 2015

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

When it comes to treating high blood pressure, not all anti-hypertensive medications are equal, and results of the ATTEMPT-CVD trial suggest that telmisartan, an angiotensin II receptor blocker (ARB) might have benefits over non-ARB treatment.

31 Aug 2015

Biocompatible scaffold enables beating heart cells to snap together like Velcro

Engineers at the University of Toronto just made assembling functional heart tissue as easy as fastening your shoes. The team has created a biocompatible scaffold that allows sheets of beating heart cells to snap together just like Velcro™.

29 Aug 2015

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Viruses are able to redirect the functioning of cells in order to infect them. Inspired by their mode of action, scientists from the CNRS and Université de Strasbourg have designed a "chemical virus" that can cross the double lipid layer that surrounds cells, and then disintegrate in the intracellular medium in order to release active compounds.

29 Aug 2015

Keratin 17 protein plays crucial role in degrading key tumor suppressor protein

Keratin 17 (K17), a protein previously believed to provide only mechanical support for cancer cells, appears to play a crucial role in degrading a key tumor suppressor protein in cancer cells named p27. This finding, published in the September 1 issue of Cancer Research, is based on the work of researchers in the Department of Pathology at Stony Brook University School of Medicine.

29 Aug 2015

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

Cells continually form membrane vesicles that are released into the cell. If this vital process is disturbed, nerve cells, for example, cannot communicate with each other. The protein molecule dynamin is essential for the regulated formation and release of many vesicles.

28 Aug 2015

UVA researchers reveal how sperm use 'harpoon' to facilitate fertilization

Could the sperm harpoon the egg to facilitate fertilization? That's the intriguing possibility raised by the University of Virginia School of Medicine's discovery that a protein within the head of the sperm forms spiky filaments, suggesting that these tiny filaments may lash together the sperm and its target.

28 Aug 2015

Scientists uncover mechanism responsible for development of adrenal gland tumors

Scientists at the Helmholtz Zentrum München have elucidated a mechanism that is responsible for the development of adrenal gland tumors. They discovered that the BMP7 protein plays a key role in this process and that it could be a possible target for future treatments. The results have been published in the journal 'Oncotarget'.

28 Aug 2015

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Researchers have discovered how a common mutation in a high-risk leukemia subtype drives the cancer's aggressiveness and have identified drugs that may work with existing precision medicines to improve survival. St. Jude Children's Research Hospital scientists led the study, which was published online today in the journal Cancer Cell.

28 Aug 2015

Research: Mechanisms behind bacterial warfare could be harnessed to target pathogenic bacteria

Two UC Santa Barbara graduate students have demonstrated how certain microbes exploit proteins in nearby bacteria to deliver toxins and kill them.

28 Aug 2015

New review article reveals Y chromosome’s role in cardiovascular and immune function, cancer

The role of sex in human disease is a growing area of research. Although estrogen (in females) and androgens (in males) are often seen as possible causes for such differences, sex chromosomes, including the male-specific Y chromosome, may also play a role. However, it has been difficult to understand how the Y chromosome could contribute to disease in men, in part because it is much more difficult to sequence than all other chromosomes.

28 Aug 2015

Researchers uncover important cellular functions that help regulate inflammation

Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation -- a discovery that could have important implications for the treatment of allergies, heart disease, and certain forms of cancer.

28 Aug 2015

Special issue of Future Science OA highlights research on protein misfolding diseases

Future Science Group today announced the publication of a special issue in Future Science OA, covering the rapidly evolving field of protein misfolding diseases.

28 Aug 2015

Scientists generate pluripotent stem cells with more stable genomes

Damaged tissue, such as pancreas, heart, and neuronal tissue, which is regenerated to treat cardiovascular diseases, diabetes, or neurodegenerative diseases. This is one of the ambitious scenarios to which regenerative medicine aspires and that is being announced as one of the great promises of twenty-first century biomedicine for the treatment of a long list of diseases affecting people today.

28 Aug 2015

Discovery could open up door for cancer research and treatment

Florida State University researchers have taken a big step forward in the fight against cancer with a discovery that could open up the door for new research and treatment options.

28 Aug 2015

Tips for cleaning your contact lenses

Today, in continued recognition of the Centers for Disease Control and Prevention's (CDC) Contact Lens Health Week, 1-800 Contacts is providing an overview on contact lens solution and how to best use it to keep lenses clean.

28 Aug 2015

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Degenerating neurons in patients with Alzheimer's disease (AD) measurably responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.

28 Aug 2015

Study sheds further light on the way APOL1 protein kills trypanosmoe

The African trypanosome Trypanosoma brucei is a blood parasite capable of infecting many mammals. Humans are provided with natural immunity against infection through the activity of the protein apolipoprotein L1 (APOL1): captured via endocytosis, APOL1 forms pores in the lysosomal membrane, leading to the death of the trypanosome.

27 Aug 2015

People who eat high protein foods have lower blood pressure and arterial stiffness

Eating foods rich in amino acids could be as good for your heart as stopping smoking or getting more exercise - according to new research from the University of East Anglia.

27 Aug 2015

G Protein News and Research

Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Scientists identify new protein that regulates severity of tissue damage caused by RA

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

Biocompatible scaffold enables beating heart cells to snap together like Velcro

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Keratin 17 protein plays crucial role in degrading key tumor suppressor protein

Scientists reveal role of dynamin and show how specific mutations impair function of dynamin

UVA researchers reveal how sperm use 'harpoon' to facilitate fertilization

Scientists uncover mechanism responsible for development of adrenal gland tumors

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Research: Mechanisms behind bacterial warfare could be harnessed to target pathogenic bacteria

New review article reveals Y chromosome’s role in cardiovascular and immune function, cancer

Researchers uncover important cellular functions that help regulate inflammation

Special issue of Future Science OA highlights research on protein misfolding diseases

Scientists generate pluripotent stem cells with more stable genomes

Discovery could open up door for cancer research and treatment

Tips for cleaning your contact lenses

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Study sheds further light on the way APOL1 protein kills trypanosmoe

People who eat high protein foods have lower blood pressure and arterial stiffness

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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