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Conventional method has minimal role in determination of PJI

In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, while measuring a patients- serum white blood cell count (WBC) and the percentage of neutrophils (PMN%), the conventional method for diagnosis, has a minimal role in the determination of PJI.

9 Feb 2012

First study to examine how changes in fitness and fatness affect heart health

Good news for active adults fighting the battle of the bulge. Exercising and getting fit may protect your heart, even if you have a few extra pounds, according to a study published in the Feb. 14 issue of the Journal of the American College of Cardiology (JACC).

9 Feb 2012

Breaks from sitting may help lower cancer risk

Sitting for extended periods can raise the chances of developing cancer even for people who exercise regularly, says recent research. In response to these findings, fitness experts at The University of Texas MD Anderson Cancer Center share advice on how to get moving in minutes.

9 Feb 2012

Primary nitinol stent implantation effective in treating atherosclerosis than balloon angioplasty

A three-year follow-up study has shown that an alternate treatment for obstructed arteries in the leg may be warranted. The results are from a clinical trial comparing primary nitinol stent implantation with balloon angioplasty. This examination of the study provides a long-term assessment of the two procedures, which is favorable for the primary stent.

9 Feb 2012

Higher blood levels of lead, cadmium may delay pregnancy in couples

Higher blood levels of cadmium in females, and higher blood levels of lead in males, delayed pregnancy in couples trying to become pregnant, according to a study by researchers at the National Institutes of Health and other academic research institutions.

9 Feb 2012

Link between coronary artery disease and prostate cancer

In a large analysis of men participating in a prostate drug trial, researchers at the Duke Cancer Institute found a significant correlation between coronary artery disease and prostate cancer, suggesting the two conditions may have shared causes.

8 Feb 2012

Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

Genzyme, a Sanofi company, announced today four-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate.

8 Feb 2012

A critical step forward in understanding how insulin secretion is regulated in the body

In a study published last week in the prestigious Proceedings of the National Academy of Sciences of the United States of America, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre (CRCHUM) has made an important step forward in understanding how insulin secretion is regulated in the body.

8 Feb 2012

Center for LAM Research and Clinical Care at BWH to conduct phase I combination drug trial

The Center for LAM Research and Clinical Care at Brigham and Women's Hospital (BWH) has been awarded a $1 million plus, four-year grant from the U.S. Department of Defense Office of the Congressionally Directed Medical Research Programs to fund their work on lymphangioleiomyomatosis.

8 Feb 2012

Elevated risk of PE occurs within first 7 days after total joint replacement surgery

The elevated risk of pulmonary embolism (PE) - a blood clot that travels from the leg to the lungs - following total joint replacement (TJR) surgery has been well established, yet little is known about the natural course and timing of this potentially fatal condition.

8 Feb 2012

New technologies safe and effective for fat removal

For many people, getting rid of excess fat can be a lifelong battle. Whether it is undesirable love handles, excess fat around the knees or flabby upper arms, pockets of fat can be difficult to reduce and sometimes diet and exercise are not enough to make a noticeable difference. Now, dermatologists are finding that the introduction of non-invasive fat removal technologies is opening the door for more people who are not candidates for liposuction to remove stubborn fat, safely and effectively.

8 Feb 2012

Elan fourth quarter total revenue increases 18% to $271.0 million

Elan Corporation, plc today reported its fourth quarter and full-year 2011 financial results.

8 Feb 2012

Padded gloves and headgear can help protect young fighters

The use of padded headgear and gloves reduces the impact that fighters absorb from hits to the head, according to newly published research from Cleveland Clinic.

8 Feb 2012

Tips to understand drug-related recall

With the new year came many drug recalls. In the first six weeks of 2012, there were at least 13 drug-related recalls. Some were due to bacterial contamination. Eight distinct bacterial contaminants were identified in one over-the-counter product.

8 Feb 2012

New skin fillers and laser technologies can correct signs of aging

As we age, our skin undergoes a number of changes affecting its texture, volume and appearance. Fortunately, dermatologists can use fillers or lasers to correct the most notable signs of aging and can recommend skin care products with added ingredients that can further repair damaged skin.

8 Feb 2012

New immunotherapy combination prolongs survival in dogs with NHL

A new immunotherapy for companion dogs with advanced-stage non-Hodgkin lymphoma (NHL) has been shown to improve survival while maintaining quality of life, according to a study published in the journal Scientific Reports.

8 Feb 2012

First sign of coronary heart disease in men could be death

The healthy heart movement in recent years has focused largely on heart disease as the No. 1 killer of women. But the same statistic is true for men, and the reality is grim: The first sign that a man has coronary heart disease could be death, says one University of Alabama at Birmingham expert.

8 Feb 2012

FDA accepts Genentech's pertuzumab BLA and grants Priority Review

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration (FDA) has accepted the company's Biologics License Application for pertuzumab and granted Priority Review.

8 Feb 2012

LE strips can have a role in rapid diagnosis of periprosthetic joint infection

Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows leukocyte esterase reagent (LE) strips, common in diagnosing urinary tract infections, can also have a role in rapid diagnosis of PJI.

7 Feb 2012

Link between inflammation-related genes and risk of ovarian cancer

In a study conducted by researchers at Moffitt Cancer Center and colleagues from 11 other institutions in the Unites States and the United Kingdom, genes that are known to be involved in inflammation were found to be related to risk of ovarian cancer.

7 Feb 2012