Therapy News and Research

RSS

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

A Phase I clinical trial of SNS-032, one of the first in a new class of drugs that inhibit cyclin-dependent kinases, demonstrated the drug's safety and potential clinical action against advanced chronic lymphocytic leukemia. Cyclin-dependent kinases are enzymatic proteins that are integrally involved in cellular metabolism, renewal and signaling, and are thought to play key roles in the growth of cancers.

20 May 2010

Targacept commences Phase 2 clinical proof of concept trial of TC-5619 in adults with ADHD

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics (TM), today announced that it has initiated a Phase 2 clinical proof of concept trial of TC-5619 in adults with attention deficit/hyperactivity disorder (ADHD). TC-5619 is a novel small molecule that is highly selective for the alpha7 neuronal nicotinic receptor, which Targacept refers to as NNR, and was discovered by Targacept scientists using Targacept's proprietary drug discovery platform known as Pentad (TM).

19 May 2010

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

TRACON Pharmaceuticals, a biotechnology company that develops targeted therapies for oncology and ophthalmology, announced today that results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 will be presented at the annual meeting of the American Society of Clinical Oncology on June 5-7, 2010 in Chicago, IL.

19 May 2010

Oncolytics Biotech initiates Phase I study of REOLYSIN and FOLFIRI in colorectal cancer patients

Oncolytics Biotech Inc. announced today that following submission to the U.S. Food and Drug Administration for review, the Company is initiating a U.S. Phase I study of REOLYSIN(R) in combination with FOLFIRI (Folinic Acid (leucovorin) + Fluorouracil (5-FU) + Irinotecan) in patients with oxaliplatin refractory/intolerant Kras mutant colorectal cancer.

19 May 2010

Long-term smoking cessation success possible with treatment philosophy and individualized information

A recently completed randomized trial compared three ways to deliver a behavioral smoking cessation program using varenicline (Chantix®): by phone, web, or both. Although phone counseling had greater treatment advantage for early cessation and appeared to increase medication adherence, no differences in abstinence outcomes were seen at six months.

19 May 2010

Research team converts astroglia into two main classes of cortical neurons

The research team led by Professor Magdalena Götz of Helmholtz Zentrum München and Ludwig-Maximilians-Universität (LMU) Munich reports a major step forward in discovering a therapy for neurodegenerative diseases such as Alzheimer's or stroke. The researchers were able to convert glial cells of the brain into two different functional classes of neurons. The findings are published on May 18th in the renowned journal PLoS Biology.

19 May 2010

Study identifies suppression as a mediator between negative emotions and desire to binge

A German study published in the current issue of Psychotherapy and Psychosomatics explores what is behind binge eating.

19 May 2010

NeoStem, Vatican's Pontifical Council collaborate to expand raise awareness of adult stem cell therapies

NeoStem, Inc.,, an international biopharmaceutical company with operations in the US and China, and the Vatican's Pontifical Council for Culture, today announced a joint initiative that includes their charitable organizations to expand research and raise awareness of adult stem cell therapies.

19 May 2010

eMedonline telemonitoring system developed to help patients transition from inpatient to outpatient setting

A clinical study is underway at Nyack Hospital to evaluate the use of cellphone-based technology to monitor medication adherence in discharged heart failure patients. The study is using the eMedonline telemonitoring system developed by Leap of Faith Technologies to help patients transition from the inpatient to outpatient setting.

19 May 2010

Cell Therapeutics reports cardiac safety results from phase II trial of pixantrone in CHOP-R regimen

Cell Therapeutics, Inc. reported today preliminary cardiac safety results from a North American randomized phase II trial which substituted pixantrone for doxorubicin in the standard CHOP-R regimen. Called PIX203, the randomized trial compared CPOP-R directly to CHOP-R in the 1st line treatment of high risk patients with diffuse large B cell non-Hodgkin's lymphoma (DLBCL, NHL).

19 May 2010

Flexible treatment delivery intervention in primary care reduces symptoms of anxiety: Study

An intervention in primary care settings that allowed a choice of cognitive behavior therapy, medication, or both, along with computer-assisted treatment support for patients with common anxiety disorders, resulted in greater improvement in anxiety symptoms and functional disability compared to usual care, according to a study in the May 19 issue of JAMA, a theme issue on mental health.

19 May 2010

Significant proportion of men with ED exhibit early signs of CAD: Review

International experts are calling for all men experiencing impotence to undergo thorough medical assessments, after an extensive review showed that a significant proportion of men with erectile dysfunction exhibit early signs of coronary artery disease.

19 May 2010

Early tracheotomy not beneficial in terms of MV duration, mortality compared to late tracheotomy

Early tracheotomy in ICU patients on mechanical ventilation (MV) did not reduce mortality when compared to later tracheotomy in a study of cardiac surgery patients requiring prolonged ventilation in a Paris study.

19 May 2010

PET scanning provides great insight into immune response

A commonly used probe for Positron Emission Tomography scanning and a new probe developed by researchers at UCLA reveal different functions in diverse cells of the immune system, providing a non-invasive and much clearer picture of an immune response in action.

19 May 2010

Two common operations for SUI help women achieve similar levels of dryness: Study

Two common operations for stress urinary incontinence help women achieve similar levels of dryness, according to a team of urologists and urogynecologists who compared the treatments in a large U.S. trial supported by the National Institutes of Health. The study is being released online May 17, 2010, by the New England Journal of Medicine to coincide with a presentation at the annual meeting of the American College of Obstetrics and Gynecology. Results will appear in the June 3 print edition.

19 May 2010

CBIT therapy helps Tourette Syndrome children manage tics

A comprehensive behavioral therapy is effective in helping children with Tourette Syndrome manage their tics, according to a study published in the May 19, 2010 special issue of the Journal of the American Medication Association (JAMA), which was dedicated to addressing mental health disorders. The research was funded by the National Institutes of Mental Health (NIMH) and involved several leading universities working in partnership with the national Tourette Syndrome Association, Inc (TSA).

19 May 2010

WHO Director-General pushes for sustained commitment to MDGs at World Health Assembly

During her opening address to the World Health Assembly in Geneva, Switzerland, on Monday, WHO Director-General Margaret Chan called for increased global efforts to reach the Millennium Development Goals, PANA/Afrique en ligne reports. Chan also set-up several global health challenges to be addressed during the five-day meeting, according to the news service.

19 May 2010

Low blood phosphorus levels associated with high death rates in African AIDS patients: Research

Low blood phosphorus levels are associated with high death rates in the initial weeks of antiretroviral therapy (ART) in AIDS patients in sub-Saharan Africa, according to new research conducted by University of Alabama at Birmingham researchers at the UAB-affiliated Centre for Infectious Disease Research in Zambia.

19 May 2010

Choir singing induces state of stimulated regeneration in IBS patients

A Swedish investigation has compared choir singing and group discussion in irritable bowel syndrome in the current issue of Psychotherapy and Psychosomatics.

19 May 2010

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

Cancer Research UK scientists have discovered sophisticated 'watchman' cells in humans that can instruct the immune system to destroy foreign invaders like viruses and cancer cells, according to research published in The Journal of Experimental Medicine.

19 May 2010

Therapy News and Research

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

Targacept commences Phase 2 clinical proof of concept trial of TC-5619 in adults with ADHD

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

Oncolytics Biotech initiates Phase I study of REOLYSIN and FOLFIRI in colorectal cancer patients

Long-term smoking cessation success possible with treatment philosophy and individualized information

Research team converts astroglia into two main classes of cortical neurons

Study identifies suppression as a mediator between negative emotions and desire to binge

NeoStem, Vatican's Pontifical Council collaborate to expand raise awareness of adult stem cell therapies

eMedonline telemonitoring system developed to help patients transition from inpatient to outpatient setting

Cell Therapeutics reports cardiac safety results from phase II trial of pixantrone in CHOP-R regimen

Flexible treatment delivery intervention in primary care reduces symptoms of anxiety: Study

Significant proportion of men with ED exhibit early signs of CAD: Review

Early tracheotomy not beneficial in terms of MV duration, mortality compared to late tracheotomy

PET scanning provides great insight into immune response

Two common operations for SUI help women achieve similar levels of dryness: Study

CBIT therapy helps Tourette Syndrome children manage tics

WHO Director-General pushes for sustained commitment to MDGs at World Health Assembly

Low blood phosphorus levels associated with high death rates in African AIDS patients: Research

Choir singing induces state of stimulated regeneration in IBS patients

Newly-discovered watchmen DCs instruct T cells to attack and destroy cancer cells

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News