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Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

Advanced Cell Technology, Inc. announced today that it has completed key animal studies in connection with its Phase I multicenter study using embryonic stem cell derived Retinal Pigment Epithelium (RPE) cells to treat patients with Stargardt's Macular Dystrophy (SMD), for which it filed an Investigational New Drug Application (IND) with the US Food and Drug Administration (FDA) in November. The studies demonstrated an excellent safety profile with no safety signals such as tumors or ectopic tissues.

24 Apr 2010

Complete revascularization reduces mortality rate in CAD patients

A 3-year, retrospective study by cardiologists from the Minneapolis Heart Institute Foundation and the University of Minnesota determined that 28.8% of patients with significant coronary artery disease (CAD) who did not undergo complete revascularization had a higher mortality rate than patients completely revascularized. Results of this study appear in the May issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

24 Apr 2010

AFREZZA Inhalation Powder reduces incidence of hypoglycemia in patients with Type 1 diabetes

Diabetes treatment regimens containing AFREZZATM (insulin human [rDNA origin]) Inhalation Powder, a well-tolerated, ultra rapid acting insulin, provide glucose control similar to standard insulin therapy along with weight loss and reduced incidence of hypoglycemia in patients with Type 1 diabetes and poorly controlled blood sugar levels, according to a two-year study presented today at the American Association of Clinical Endocrinologists 19th Annual Meeting (Poster #283).

24 Apr 2010

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

Monitoring rejection in heart transplantation patients with a simple blood test co-developed by NewYork-Presbyterian Hospital/Columbia University Medical Center physician-scientist Dr. Mario Deng in 2005 can safely reduce their need for invasive heart-muscle biopsies, a new study has found.

24 Apr 2010

Paradigm Rehab and Nursing signs contract to use PSA's Mobipen Care System

Patient Access Solutions, Inc., a provider of digital pen and paperwork technologies that provide the healthcare industry a graceful migration to Electronic Medical Records, today announced that Paradigm Rehab and Nursing has signed a contract to use the PASHealth D-PAS, digital pen and paper, Mobipen Care System to improve the standard of the service within their homecare industry.

24 Apr 2010

Karolinska University Hospital acquires Leksell Gamma Knife Perfexion fifth generation radiosurgery system

Prof. Lars Leksell (1907-1986), inventor of the radiosurgical instrument that bears his name and a faculty member of Karolinska University Hospital (Solna, Sweden), performed the world's first Gamma Knife® surgery at nearby Sophiahemmet Hospital, the location of the first Leksell Gamma Knife. Karolinska University Hospital recently acquired Elekta's fifth generation radiosurgery system, Leksell Gamma Knife® Perfexion™.

24 Apr 2010

CAT may improve QOL in pediatric oncology patients undergoing therapy: Researchers

As health care professionals continue placing greater emphasis on the quality of life of childhood cancer patients, researchers have found that creative arts therapy may improve QOL in pediatric oncology patients undergoing therapy.

24 Apr 2010

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

New data show improved outcomes, better survival rates and lower costs with the use of continuous flow mechanical circulatory support devices in patients awaiting heart transplants. Research will be presented this week during symposia at the International Society for Heart and Lung Transplantation (ISHLT) 30th Annual Meeting and Scientific Session at the Hilton Chicago.

24 Apr 2010

Moffitt Cancer Center reports increasing interest in ERCC1 Analysis test for selecting chemotherapy for NSCLC

Moffitt Cancer Center announces steadily growing interest in the ERCC1 Analysis, the first test developed for selecting chemotherapy for Non Small Lung Cancer patients. Each year, more than 200,000 Americans are diagnosed with lung cancer.

24 Apr 2010

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Cardiola AG announced today that the Company's CE-Marked m.pulse® Muscular CounterPulsation ("MCP")-based system demonstrated "an immediate improvement of cardiac output with non-invasive means" in a patient population of advanced yet stable chronic heart failure. The effects could be shown in 22 patients over three consecutive days.

24 Apr 2010

Urigen Pharmaceuticals requests FDA meeting for advancing URG101 clinical program

Urigen Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development of treatments for urological disorders and pain, announced today that it has filed a request for an FDA meeting to advance the URG101 clinical program and mutually agreed with Oceana Therapeutics, Inc. to terminate their Consulting Agreement effective immediately.

24 Apr 2010

Prevention and nonsurgical treatment options to prevent low back pain and protect spine

Back and neck problems can be caused by a herniated disc, spinal stenosis, injury, strain or osteoarthritis. "Although more than 75 percent of Americans will experience some back pain during their lifetime, about 90 percent of cases are resolved without surgery," stated John K. Ratliff, MD, FACS, a Philadelphia spine surgeon and American Association of Neurological Surgeons spokesperson.

24 Apr 2010

Karolinska University Hospital acquires Elekta's fifth generation radiosurgery system

Prof. Lars Leksell (1907-1986), inventor of the radiosurgical instrument that bears his name and a faculty member of Karolinska University Hospital (Solna, Sweden), performed the world's first Gamma Knife surgery at nearby Sophiahemmet Hospital, the location of the first Leksell Gamma Knife. Karolinska University Hospital recently acquired Elekta's fifth generation radiosurgery system, Leksell Gamma Knife Perfexion.

24 Apr 2010

Johns Hopkins scientist receives AACR Award for Outstanding Achievement in Cancer Research

Joshua T. Mendell, M.D., Ph.D., an associate professor in the McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins University School of Medicine, and a Howard Hughes Medical Institute Early Career Scientist, is the recipient of the 30th annual American Association for Cancer Research Award for Outstanding Achievement in Cancer Research.

24 Apr 2010

Researchers discover and characterize general mechanism controlling transcription elongation in bacteria

Researchers from NYU Langone Medical Center have discovered and characterized a general mechanism that controls transcription elongation in bacteria. The mechanism, described in the April 23 issue of Science, relies on physical cooperation between a moving ribosome and RNA polymerase (RNAP) that allows for a precise adjustment of the transcriptional yield in response to translational needs. The study could lead to the development of new ways to interfere with bacterial gene expression and serve as a new target for antimicrobial therapy.

23 Apr 2010

Oncolytics Biotech completes Phase I enrollment in Phase I/II trial of REOLYSIN for recurrent malignant gliomas

Oncolytics Biotech Inc. announced today that it has completed Phase I patient enrollment in its Phase I/II clinical trial to investigate the use of REOLYSIN(R) for patients with recurrent malignant gliomas (REO 007). The principal investigator is Dr. James Markert, Division Director of Neurosurgery, and Professor, Neurosurgery and Physiology, the University of Alabama at Birmingham.

23 Apr 2010

Study: 28.8% of CAD patients who fails to undergo complete revascularization face higher mortality rate

23 Apr 2010

Advances in understanding of cardiac-specific genes in heart development

Researchers at the Texas Heart Institute at St. Luke's Episcopal Hospital (THI at St. Luke's) announced today the results of research which they believe marks a significant advance in understanding how cardiac-specific genes are turned on during the development of the heart in mice embryos.

23 Apr 2010

MMV supports Pfizer's AZCQ clinical trial for intermittent preventive treatment of malaria in pregnant women

Pfizer Inc. and Medicines for Malaria Venture (MMV) entered into an agreement for the development, access and delivery of a fixed-dose combination treatment consisting of azithromycin dihydrate (AZ) and chloroquine phosphate (CQ) for the Intermittent Preventive Treatment of P. falciparum malaria in pregnancy (IPTp). There is currently an unmet need for new treatment options and the World Health Organization (WHO) estimates that some 30 million pregnant women are at risk for malaria in endemic areas in Africa each year.

23 Apr 2010

Drinking lemonade prevents kidney stone formation

We've all heard the expression, "when life gives you lemons, make lemonade." Passing a kidney stone would qualify for one of life's "lemons," but did you know that drinking lemonade has been shown to prevent them?

23 Apr 2010

Therapy News and Research

Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

Complete revascularization reduces mortality rate in CAD patients

AFREZZA Inhalation Powder reduces incidence of hypoglycemia in patients with Type 1 diabetes

AlloMap molecular expression test reduces need for invasive heart-muscle biopsies

Paradigm Rehab and Nursing signs contract to use PSA's Mobipen Care System

Karolinska University Hospital acquires Leksell Gamma Knife Perfexion fifth generation radiosurgery system

CAT may improve QOL in pediatric oncology patients undergoing therapy: Researchers

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

Moffitt Cancer Center reports increasing interest in ERCC1 Analysis test for selecting chemotherapy for NSCLC

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Urigen Pharmaceuticals requests FDA meeting for advancing URG101 clinical program

Prevention and nonsurgical treatment options to prevent low back pain and protect spine

Karolinska University Hospital acquires Elekta's fifth generation radiosurgery system

Johns Hopkins scientist receives AACR Award for Outstanding Achievement in Cancer Research

Researchers discover and characterize general mechanism controlling transcription elongation in bacteria

Oncolytics Biotech completes Phase I enrollment in Phase I/II trial of REOLYSIN for recurrent malignant gliomas

Study: 28.8% of CAD patients who fails to undergo complete revascularization face higher mortality rate

Advances in understanding of cardiac-specific genes in heart development

MMV supports Pfizer's AZCQ clinical trial for intermittent preventive treatment of malaria in pregnant women

Drinking lemonade prevents kidney stone formation

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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