Malignant News and Research

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Rituximab useful for advanced indolent lymphoma

A new study has found for the first time that maintenance therapy with the novel antibody, rituximab (MR) following cyclophosphamide, vincristine and prednisone (CVP) therapy improves progression-free survival in patients with stage III-IV indolent lymphoma, according to Howard S. Hochster, M.D. of NYU Langone Medical Center, lead author of a recent study published online ahead of print in the Journal of Clinical Oncology.

11 Mar 2009

Small molecules block cancer gene

Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to those of the small molecules, said a Baylor College of Medicine researcher in a report that appears in the current online issue of the journal PLoS One (Public Library of Science ONE).

11 Mar 2009

Should breast tissue be screened for cancer after mammoplasty?

Young women undergoing cosmetic breast reduction surgery are being screened for cancer without their informed consent, according to a paper published on bmj.com.

11 Mar 2009

Advances in stem cell research

Scientists at The University of Texas Health Science Center at Houston are on the forefront of stem cell research, developing novel therapies designed to generate heart cells, repair traumatic lung injuries, grow new bone and stanch the spread of cancer cells.

8 Mar 2009

Curry ingredient curcumin makes membranes behave for better health

Revered in India as "holy powder," the marigold-colored spice known as turmeric has been used for centuries to treat wounds, infections and other health problems.

8 Mar 2009

Scientists make a strain of E. coli glow under fluorescent light

A team of Michigan Technological University researchers led by Associate Professor of Chemistry Haiying Liu has discovered how to make a strain of E. coli glow under fluorescent light.

5 Mar 2009

European Commission and US FDA approve intravenous formulation of temozolomide

Schering-Plough Corporation (NYSE:SGP) today announced that the European Commission and the US FDA both approved the intravenous (IV) formulation of temozolomide as an alternative to the already approved oral form of the drug.

5 Mar 2009

Stereotactic body radiotherapy doubles survival in lung cancer

Countless people have heard the phrase, "You have lung cancer," but only 50 can say they've completed a new treatment at Temple University that doubles their chances of surviving the deadly disease - and without the conventional radiation regimen or surgery.

4 Mar 2009

FDA clears Cellectar's IND application for lead drug candidate

Cellectar, Inc. has announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its (131)I-CLR1404 drug candidate for testing in patients with advanced solid malignancies.

3 Mar 2009

Discovery of gene involved in pancreatic cancer

Researchers from the University of Michigan Comprehensive Cancer Center have identified a gene that is overexpressed in 90 percent of pancreatic cancers, the most deadly type of cancer.

2 Mar 2009

Liver tumors associated with metabolic syndrome differ from other tumors

Liver cancer in patients whose only risk factor is metabolic syndrome has distinct forms and structures compared to other liver tumors.

25 Feb 2009

New cancer treatment stops aggressive sarcomas

After all standard treatments had failed, a new cancer treatment has stopped the growth of aggressive sarcomas in two recent patients. These results are similar to the new protocol's previous success against several cancers, including melanoma, pancreatic, colon, mesothelioma and other sarcomas.

25 Feb 2009

Waiting for biopsy results may adversely affect health

Women who've had a breast biopsy know the anxiety of waiting for the results, but that stress may cause adverse health effects, according to a new study published in the March issue of Radiology.

24 Feb 2009

European Society of Cardiology reaffirms advice on cardiovascular risks associated with long-haul flights

Following a review by The Lancet of the medical issues associated with commercial air travel, the European Society of Cardiology has reaffirmed its advice about the risks of venous thromboembolism (VTE), whose risk, according to The Lancet, is increased "up to four-fold" by long-haul flight.

24 Feb 2009

Anyone can be affected by mouth cancer

Mouth cancer (also called oral cancer) is a malignant growth which can occur in any part of the mouth including the lips and tongue.

22 Feb 2009

GABAergic system shows promise as molecular target for liver cancer therapy

Although GABA and GABA receptors function as an inhibitory neurotransmitter in the mature CNS, abnormal levels of gene and protein expression of some GABA receptor subunits have been detected in many malignant tumors, such as ð subunit in pancreatic cancer.

18 Feb 2009

Study on ustekinumab for treatment of psoriatic arthritis published

A group of patients suffering from potentially debilitating psoriatic arthritis showed significant and prolonged improvement after treatment with ustekinumab, according to data from a randomized, double-blind, placebo-controlled study in patients with moderate to severe psoriatic arthritis (PsA).

11 Feb 2009