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Scientists develop tiny fluorescent probe that seeks out GLUT5 and detects cancer cells

Determining the presence of cancer, as well as its type and malignancy, is a stressful process for patients that can take up to two weeks to get a diagnosis. With a new bit of technology--a sugar-transporting biosensor--researchers at Michigan Technological University hope to reduce that timeframe down to minutes.

20 Apr 2018

New microscopy techniques allow quasi-biochemical studies on living T cells

A joint study by the TU Wien and the Vienna School of Medicine has now led to a surprising result. While most opinion leaders in the field reasoned that T cell receptors must interact with one another for effective immune-signaling, the Viennese study shows: T cell receptors act alone. The study has now been published in the journal Nature Immunology.

19 Apr 2018

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios.

19 Apr 2018

'Gut-on-a-chip' model recreates intestinal matrix critical for nutrient absorption

The difficulties of conducting research on the human gut are substantial: the presence of trillions of bacterial cells interacting with human cells and each other, constant environmental changes every time food is consumed and zero chance of conducting trials that control for all those moving parts.

18 Apr 2018

Researchers discover unique protein in malaria parasite that could be new drug target

Over a thousand people die from malaria every day. The disease is caused by a single-cell parasite (protozoan) that is transmitted by mosquitoes. Anti-malaria efforts currently focus on effective diagnostics, mosquito nets, insecticides and drugs.

18 Apr 2018

Researchers develop new method to study activity of inflammatory cells

The process that the body sets in motion in the event of inflammation is complex, but also impressive. The main role here is played by immune cells migrating from the blood into the tissue to fight the inflammation.

17 Apr 2018

Two MDC researchers win ERC funding worth several million euros

Basic researchers Gary Lewin and Norbert Hübner are investigating the molecular mechanisms underlying neurological and heart diseases. Their focus is on understanding the anchoring of ion channels and micropeptides in heart muscle cells.

13 Apr 2018

Glucose metabolism is key to neural network development, finds study

A new study has found that glucose metabolism is critical for the development of neural networks in the brain.

13 Apr 2018

Biologists discover surprising, additional function for soluble form of SNARE protein

In 2013, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their contributions to uncovering the mechanisms governing vesicle transport in cells. Their explanations provided both a conceptual and a mechanistic understanding of basic processes at the most fundamental level.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

FDA grants clearance for first contact lens with light-adaptive technology

The U.S. Food and Drug Administration today cleared the first contact lens to incorporate an additive that automatically darkens the lens when exposed to bright light.

11 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Research reveals how bacteria prepare sticky adhesion protein

Researchers at Harvard Medical School, the University of California, San Francisco, and the University of Georgia have described how the protein that allows strep and staph bacteria to stick to human cells is prepared and packaged.

6 Apr 2018

Researchers discover potential new therapeutic target for Ewing sarcoma

The sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, has identified a potential new therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents, and a tumor known by its aggressiveness and tendency to metastasize.

5 Apr 2018

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

4 Apr 2018

New discovery in cell biology can have implications for research into autoimmune diseases

Research carried out by the University has discovered the first data on an organelle that is really important in human cells in an ancient organism distantly related to humans.

3 Apr 2018

Iowa State University researcher is searching for new way to fight superbugs

Vincenzo Venditti, an assistant professor of chemistry at Iowa State University, is searching for a new kind of antibiotic in the fight against superbugs.

2 Apr 2018

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV infections. There has been a 63 percent rise in gonorrhea in Australia over the past five years.

30 Mar 2018

Membrane News and Research

Scientists develop tiny fluorescent probe that seeks out GLUT5 and detects cancer cells

New microscopy techniques allow quasi-biochemical studies on living T cells

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

'Gut-on-a-chip' model recreates intestinal matrix critical for nutrient absorption

Researchers discover unique protein in malaria parasite that could be new drug target

Researchers develop new method to study activity of inflammatory cells

Two MDC researchers win ERC funding worth several million euros

Glucose metabolism is key to neural network development, finds study

Biologists discover surprising, additional function for soluble form of SNARE protein

Research reveals immune suppressive role of soluble antibodies in tumor progression

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

FDA grants clearance for first contact lens with light-adaptive technology

Removal of single mitochondrial protein leads to severe inflammation

Resistance training enhances cellular recycling in muscle cells

Research reveals how bacteria prepare sticky adhesion protein

Researchers discover potential new therapeutic target for Ewing sarcoma

New discovery may offer insight into treating sickle cell anemia and other blood disorders

New discovery in cell biology can have implications for research into autoimmune diseases

Iowa State University researcher is searching for new way to fight superbugs

Monash scientists discover how gonorrhea-causing superbug evades the immune system

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