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Study unravels cellular and molecular mechanisms behind dermal condensate formation

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now.

20 Aug 2018

Innovative platform developed to destroy cancer cells

The new treatment will serve as both diagnosis and treatment of malignant tumors. This breakthrough in the technologies of cancer diagnosis and treatment was made by an interdisciplinary Russian-German collaboration of chemists, physicists, and biologists from NUST MISIS, Lomonosov Moscow State University, Pirogov Russian National Research Medical University (RNRMU), and the University of Duisburg-Essen (Germany).

17 Aug 2018

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.

16 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

Innovative oncofertility program launched by RMA of New York and Mount Sinai Health System

Reproductive Medicine Associates of New York, a Manhattan-based fertility center, and the Mount Sinai Health System have launched an innovative, integrated oncofertility program at The Blavatnik Family – Chelsea Medical Center at Mount Sinai to provide individuals and couples the benefit of advanced medical technologies to help with someday building their families.

15 Aug 2018

New study explains why women get more migraines than men

Research published today reveals a potential mechanism for migraine causation which could explain why women get more migraines than men.

14 Aug 2018

New strategy accelerates, automates process of prototype molecule optimization

The search for new medicinal molecules with predetermined properties is a rather complex, expensive and time-consuming process, especially in oncology.

14 Aug 2018

New laboratory-synthesized molecule appears to fight malaria effectively

A novel laboratory-synthesized molecule based in natural compounds found in marine gliding bacteria - known as marinoquinolines - is a strong candidate for the development of a new antimalarial drug.

10 Aug 2018

Researchers describe new class of potent inhibitors against amyloid plaques

Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available.

9 Aug 2018

Study reveals cellular pathway used by Ebola virus to enter cells

A new study at Texas Biomedical Research Institute is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to establish replication.

9 Aug 2018

New drug makes rats to self-administer alcohol less frequently

Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns.

9 Aug 2018

New drug delivery system delivers anticancer drugs that reduce tumor size

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells. CSCs are related to cancer progression and dissemination, so it's necessary to eradicate CSCs in order to cure cancer.

9 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Researchers develop drug-delivery system that allows rapid response to heart attacks

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention.

7 Aug 2018

Researchers develop 3D model of human placenta

The placenta is the organ connecting mother and embryo. Its main functions are the exchange of nutrients, gases and metabolic products and the production of hormones and other substances essential for embryonic development.

3 Aug 2018

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Implantation of a stent-like flow diverter can offer one option for less invasive treatment of brain aneurysms – bulges in blood vessels – but the procedure requires frequent monitoring while the vessels heal.

2 Aug 2018

Researchers find possible active substance that may cure hepatitis E

An international team of researchers has now found a possible active substance against the virus in the naturally occurring substance silvestrol.

1 Aug 2018

Ortho Clinical Diagnostics receives FDA approval for two hepatitis B assays

Ortho Clinical Diagnostics, a global leader of in vitro diagnostics, has received approval from the U.S. Food and Drug Administration for Ortho's VITROS Immunodiagnostic Products HBeAg Assay and the VITROS Immunodiagnostic Products Anti-HBe Assay for use on Ortho's VITROS 3600 Immunodiagnostic System and Ortho's VITROS 5600 Integrated System.

31 Jul 2018

EKF Diagnostics to showcase new Stanbio GA assay kit at AACC 2018

EKF, announces it will highlight a new Stanbio Chemistry Glycated Albumin assay kit and its newly FDA cleared DiaSpect Tm hemoglobin point of care analyzer.

From EKF Diagnostics 31 Jul 2018

Researchers describe strategy used by Oropouche virus to replicate in human cells

The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo in Brazil and international collaborators in an article published in the journal PLOS Pathogens.

31 Jul 2018

in vitro News and Research

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Innovative platform developed to destroy cancer cells

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Innovative oncofertility program launched by RMA of New York and Mount Sinai Health System

New study explains why women get more migraines than men

New strategy accelerates, automates process of prototype molecule optimization

New laboratory-synthesized molecule appears to fight malaria effectively

Researchers describe new class of potent inhibitors against amyloid plaques

Study reveals cellular pathway used by Ebola virus to enter cells

New drug makes rats to self-administer alcohol less frequently

New drug delivery system delivers anticancer drugs that reduce tumor size

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Researchers develop drug-delivery system that allows rapid response to heart attacks

Researchers develop 3D model of human placenta

Nanostructured sensor system offers active monitoring of brain aneurysm treatment

Researchers find possible active substance that may cure hepatitis E

Ortho Clinical Diagnostics receives FDA approval for two hepatitis B assays

EKF Diagnostics to showcase new Stanbio GA assay kit at AACC 2018

Researchers describe strategy used by Oropouche virus to replicate in human cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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