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Mesoblast receives FDA clearance for heart attack stem cell trial

Australia's adult stem cell company, Mesoblast Limited has announced that the United States Food and Drug Administration (US FDA) has cleared the Investigational New Drug Submission (IND) of its US-based sister company, Angioblast Systems Inc., to commence a Phase 2 clinical trial of its allogeneic, or 'off-the-shelf', adult stem cells for patients with heart attacks.

4 May 2007

FDA approves new indication for FRAGMIN for the extended treatment of symptomatic venous thromboembolism

The U.S. Food and Drug Administration (FDA) has approved a new indication for FRAGMIN (dalteparin sodium injection), for the extended treatment of symptomatic venous thromboembolism (VTE) to reduce the recurrence of VTE in patients with cancer.

4 May 2007

Nutritional benefits of egg consumption

Nine studies presented at the Experimental Biology 2007 meeting support the growing body of research on the nutritional benefits of egg consumption, including its promotion of weight loss and its role in providing choline, an essential nutrient often lacking in the diet that promotes brain and memory development and function.

4 May 2007

Statins reduce risk of stroke and heart attack

People whose cholesterol improved after one month on cholesterol-lowering drugs called statins reduced their risk of stroke and heart attack, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 , May 5, 2007.

4 May 2007

Reclast found to cause abnormal heart rhythms

An osteoporosis drug with the potential to cut the risk of spine fractures by 70 percent and the chance of hip fractures by 41 percent, has been found to have an adverse side effect on some women.

3 May 2007

Just to confuse you even more - HRT now linked to Alzheimer's!

To add to the utter confusion many women are feeling with regard to Hormone replacement therapy (HRT), new research is now suggesting HRT may reduce a woman's risk of Alzheimer's disease.

3 May 2007

Use of antithrombotics means more intracerebral haemorrhagic stroke deaths in over 75s

A study suggests that the number of pensioners over 75 dying from intracerebral haemorrhagic stroke has increased in the last 25 years due to use of antithrombotic drugs.

2 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

11 percent of American women smoke during pregnancy

The negative effects of nicotine exposure to their fetuses and newborns are significant.

2 May 2007

New treatments have major impact on heart failure rates

Deaths from severe heart attacks following admission to hospital have nearly halved in six years as a result of advances in medical treatment.

2 May 2007

New tool refines heart risk prediction

For about 10 years, the Framingham risk score has been used to estimate a person's chances of having a heart attack based on just six bits of information -- age, sex, total cholesterol, HDL cholesterol, smoking status, and systolic blood pressure.

2 May 2007

Statin drugs also may help reduce risk of heart failure

Statin drugs, known primarily for their ability to lower cholesterol, also may reduce the overactive sympathetic nervous system response that contributes to the worsening of heart failure and increases the risk of sudden cardiac death, two University of Missouri-Columbia researchers have found. Heart failure is the leading cause of morbidity and mortality in the United States.

2 May 2007

Migraines during pregnancy linked to vascular diseases

Migraines during pregnancy are strongly linked to vascular diseases, such as stroke and heart disease, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28, May 5, 2007.

2 May 2007

Adverse health outcomes after Hurricane Katrina among children and adolescents with chronic conditions

Children and teenagers in New Orleans with chronic medical conditions at the time of Hurricane Katrina were more likely than other children to have worsening of physical and psychological symptoms, develop new symptoms, miss doctor appointments and run out of medications in the wake of the disaster.

2 May 2007

Variants of two genes involved in the inflammatory system linked to cognitive decline after heart surgery

Duke University Medical Center researchers believe their findings could help physicians identify patients at risk of suffering mental decline after heart surgery and raises the possibility that these patients could be treated with drugs that are known to dampen the inflammatory response.

2 May 2007

Improving outcomes for patients with acute coronary syndrome

Recent changes in the recommended treatments used for patients hospitalized for acute coronary syndromes, such as a heart attack, are associated with reductions in the rates of heart failure, stroke, heart attack and death, according to a study in the May 2 issue of JAMA .

2 May 2007

One out of four people don't know they have hypertension

High blood pressure is a major risk factor for heart attack, stroke, and renal failure, but one out of four people don't even know they have it.

2 May 2007

Efforts to standardize heart care are working

People who suffer a heart attack or severe chest pain today are much less likely to die, or to experience long-lasting effects, than their counterparts even a few years ago, according to a new international study in the May 3 issue of the Journal of the American Medical Association.

2 May 2007

Levosimendan compared to dobutamine for decompensated heart failure

The drug levosimendan did not improve survival for patients with decompensated heart failure when compared with a more widely-used treatment for this condition, dobutamine, according to a study in the May 2 issue of JAMA.

2 May 2007

Why do some people get fat even when they eat relatively little?

What creates that irresistible urge for a bag of potato chips or a hunk of chocolate cake, as opposed to a nice crisp apple? Can food urges be irresistible?

2 May 2007