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Women with recurrent ovarian cancer survive longer after treatment with cediranib

Women with ovarian cancer that has recurred after chemotherapy have survived for longer after treatment with a biological therapy called cediranib, according to new results to be presented today (Monday) at the 2013 European Cancer Congress.

30 Sep 2013

Scientists discover two new compounds that could help treat CF patients having common mutation

Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes), led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation.

30 Sep 2013

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

New results from a trial of an antibody that helps the immune system to recognise and attack cancer cells have shown particularly encouraging responses in patients who are smokers or former smokers.

30 Sep 2013

Discoveries pave way for use of new therapies for advanced thyroid cancer

For many years, patients with advanced thyroid cancer faced bleak prospects and no viable treatment options. But now, building on recent discoveries about the genetics and cell signaling pathways of thyroid tumors, researchers are developing exciting new weapons against the disease, using kinase inhibitors that target tumor cell division and blood vessels.

30 Sep 2013

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

The first Phase II study to investigate the use of the anti-cancer drug, everolimus, for the initial treatment of advanced papillary kidney cancer has shown that it is successful in slowing or preventing the spread of the disease, according to research to be presented today (Sunday) at the 2013 European Cancer Congress.

29 Sep 2013

Study provides new insights into type 1 diabetes pathology

Joslin researchers have identified immune cells that promote growth of beta cells in type 1 diabetes. This study provides further evidence of a changed role for immune cells in type 1 diabetes pathology. The study appears online today and will also appear in the January issue of Diabetes.

29 Sep 2013

Researchers discover severe health consequences of folic acid deficiency

Researchers from the universities of Calgary and Cambridge, UK, have discovered that a mutation in a gene necessary for the metabolism of folic acid not only impacts immediate offspring but can also have detrimental health effects, such as spina bifida and heart abnormalities, on subsequent generations.

29 Sep 2013

c-Fos oncogene cab be important target for understanding and treatment of cancer

The c-Fos oncogene has traditionally been linked to cellular activities related to cancer, such as cell division, differentiation-conversion from one cell type to another-or survival. Any alteration of these activities can set off the development of tumours, which has made c-Fos an important target for the understanding and treatment of cancer.

29 Sep 2013

Pan-Cancer Initiative: Patterns Emerge Across Diverse Tumor Types

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27 Sep 2013

SBIR Awards Etubics $1.5M To Manufacture Breast Cancer Immunotherapy

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27 Sep 2013

Psoriasis and the nervous system: an interview with Dr Nicole Ward, Case Western Reserve University

The prevalence of skin disease exceeds that of obesity, hypertension or cancer. One in three individuals in the United States suffers with a skin disease, with ~2-3% of the American population suffering from psoriasis.

27 Sep 2013

Immunologic checkpoint inhibitor shows promise in malignant mesothelioma

Tremelimumab, one of a new class of immunomodulatory monoclonal antibodies, has shown encouraging clinical activity and acceptable tolerability in patients with chemotherapy-resistant malignant mesothelioma, results of a single-arm phase II study show.

27 Sep 2013

Time to first cigarette independently predicts lung cancer

The time to first cigarette after waking is an independent risk factor for lung cancer, a Japanese case-control study has found.

27 Sep 2013

Sister stem cells display considerable differences despite having identical DNA

Scientists have used a brand new technique for examining individual stem cells to uncover dramatic differences in the gene expression levels - which genes are turned 'up' or 'down'- between apparently identical 'sister' pairs.

27 Sep 2013

Dynamics of the mitochondria linked to obesity

Becoming obese or remaining lean can depend on the dynamics of the mitochondria, the body's energy-producing "battery," according to two new studies by Yale School of Medicine researchers featured as the cover story in the Sept. 26 issue of the journal Cell.

27 Sep 2013

Length of telomere may help determine prostate cancer patient's prognosis

Like the plastic caps at the end of shoelaces, telomeres protect — in their case — the interior-gene containing parts of chromosomes that carry a cell's instructional material. Cancer cells are known to have short telomeres, but just how short they are from cancer cell to cancer cell may be a determining factor in a prostate cancer patient's prognosis, according to a study led by Johns Hopkins scientists.

27 Sep 2013

Genomic instability in CFS is associated with less favorable outcome in patients with CaP

Detailed evaluation of a prostate cancer tumor biopsy may predict treatment outcomes for image-guided radiation therapy (IGRT) or surgery for prostate cancer, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.

27 Sep 2013

B Cell News and Research

Women with recurrent ovarian cancer survive longer after treatment with cediranib

Scientists discover two new compounds that could help treat CF patients having common mutation

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

Discoveries pave way for use of new therapies for advanced thyroid cancer

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

Study provides new insights into type 1 diabetes pathology

Researchers discover severe health consequences of folic acid deficiency

c-Fos oncogene cab be important target for understanding and treatment of cancer

Pan-Cancer Initiative: Patterns Emerge Across Diverse Tumor Types

SBIR Awards Etubics $1.5M To Manufacture Breast Cancer Immunotherapy

Psoriasis and the nervous system: an interview with Dr Nicole Ward, Case Western Reserve University

Immunologic checkpoint inhibitor shows promise in malignant mesothelioma

Time to first cigarette independently predicts lung cancer

Sister stem cells display considerable differences despite having identical DNA

Dynamics of the mitochondria linked to obesity

Length of telomere may help determine prostate cancer patient's prognosis

Genomic instability in CFS is associated with less favorable outcome in patients with CaP

Scientists unravel secrets of mechanism that snips our genes

New imaging technique reveals first 3D pictures of chromosome structure

VVRP receives contract from NIH to continue its work as Vaccine and Treatment Evaluation Units

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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