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BioFire Diagnostics submits FilmArray GI Panel to FDA for 510(k) clearance

BioFire Diagnostics, LLC today announced that it has submitted the FilmArray Gastrointestinal (GI) Panel to the U.S. Food and Drug Administration for 510(k) clearance. The comprehensive FilmArray GI Panel tests for over 20 common bacteria, viruses and parasites that cause infectious diarrhea.

18 Feb 2014

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Chelsea Therapeutics International, Ltd. today announced that the U.S. Food and Drug Administration granted accelerated approval of NORTHERA (droxidopa) for the treatment of symptomatic neurogenic orthostatic hypotension (NOH). NORTHERA is the first and only therapy approved by the FDA which demonstrates symptomatic benefit in patients with NOH.

18 Feb 2014

First Edition: February 18, 2014

Kaiser Health News staff writer Jay Hancock, working in collaboration with USA Today, reports: "Congratulations. You bought insurance through one of the online Affordable Care Act exchanges, possibly after days or weeks of trying to get the site to work. Don't relax. Joining the plan is only the first challenge. Now you have to understand it. Policies sold through the online portals -- to more than 3 million people so far -- cover essential benefits and put a cap on your out-of-pocket medical costs. But you need to follow the rules" (Hancock, 2/17).

18 Feb 2014

High levels of stress hormone cortisol may contribute to risk aversion in traders

High levels of the stress hormone cortisol may contribute to the risk aversion and 'irrational pessimism' found among bankers and fund managers during financial crises, according to a new study.

18 Feb 2014

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Many vaccines, including those for influenza, polio, and measles, consist of a killed or disabled version of a virus. However, for certain diseases, this type of vaccine is ineffective, or just too risky.

18 Feb 2014

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

18 Feb 2014

Scientists discover link between ageing process and hormone released from muscle after exercise

Scientists from Aston University (UK) have discovered a potential molecular link between Irisin, a recently identified hormone released from muscle after bouts of exercise, and the ageing process.

18 Feb 2014

Blood pressure effects unclear in long-term stroke survivors

Long-term survivors of stroke whose blood pressure is at target levels have worse outcomes than those with slightly elevated levels, research suggests.

17 Feb 2014

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders and migraine headaches.

17 Feb 2014

Researchers identify new type of regulatory blood cells that can combat brain inflammation

Hyperactivity of our immune system can cause a state of chronic inflammation. If chronic, the inflammation will affect our body and result in disease. In the devastating disease multiple sclerosis, hyperactivity of immune cells called T-cells induce chronic inflammation and degeneration of the brain. Researchers at BRIC, the University of Copenhagen, have identified a new type of regulatory blood cells that can combat such hyperactive T-cells in blood from patients with multiple sclerosis. By stimulating the regulatory blood cells, the researchers significantly decreased the level of brain inflammation and disease in a biological model.

17 Feb 2014

New research points to potential target for treating triple negative breast cancer

New research from the University of Michigan Comprehensive Cancer Center and Georgia Regents University finds that a protein that fuels an inflammatory pathway does not turn off in breast cancer, resulting in an increase in cancer stem cells. This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.

17 Feb 2014

Researchers use new technique that can partially move tumors from inoperable locations in brain

One factor that makes glioblastoma cancers so difficult to treat is that malignant cells from the tumors spread throughout the brain by following nerve fibers and blood vessels to invade new locations.

17 Feb 2014

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

A Democratic candidate who has explicitly defended Obamacare holds a slight lead in a special congressional election in Florida that both parties are eyeing as a test of the political impact of the healthcare law. A poll released Thursday by the Tampa Bay Times shows Democrat Alex Sink leading her Republican opponent, David Jolly, 42% to 35% among people considered likely to vote in the March 11 special election.

17 Feb 2014

Study explains clinical, public health challenges for use of statins in treatment of heart attacks

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean, and Ira J. Gelb, M.D., emeritus professor of cardiology and senior advisor to the dean for pre-baccalaureate programs at FAU's Charles E. Schmidt College of Medicine, have published an invited editorial in the current issue of Cardiology about the clinical and public health challenges to increase utilization of statins in the treatment and prevention of heart attacks and strokes.

17 Feb 2014

Vitamin C may reduce risk of most common type of hemorrhagic stroke, says study

Eating foods that contain vitamin C may reduce your risk of the most common type of hemorrhagic stroke, according to a study released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.

17 Feb 2014

Extreme loneliness can increase premature death by 14% in older adults

Feeling extreme loneliness can increase an older person's chances of premature death by 14 percent, according to research by John Cacioppo, professor of psychology at the University of Chicago.

17 Feb 2014

Discovery opens door for more targeted treatments for cancer patients

Cancer patients could one day experience fewer side effects from chemotherapy following a discovery that opens the door for more targeted treatments.

16 Feb 2014

Research provides new insight into the effect of misfolded proteins in neurodegenerative disorders

Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.

16 Feb 2014

Mobile compression device just as effective as blood thinners in preventing DVT after joint surgery

Research from The Shiley Center for Orthopaedic Research and Education at Scripps Clinic could change how patients are treated to prevent blood clots after joint replacement surgery. A study published as the lead article in the current issue of the Journal of Bone and Joint Surgery determined that after lower extremity joint replacement surgery a mobile compression device was just as effective as blood thinners in preventing deep vein thrombosis (DVT), but without negative side effects including bleeding complications.

15 Feb 2014

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

The elusive progenitor cells that give rise to innate lymphoid cells-a recently discovered group of infection-fighting white blood cells-have been identified in fetal liver and adult bone marrow of mice, researchers from the University of Chicago report early online in the journal Nature.

14 Feb 2014

Blood News and Research

BioFire Diagnostics submits FilmArray GI Panel to FDA for 510(k) clearance

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

First Edition: February 18, 2014

High levels of stress hormone cortisol may contribute to risk aversion in traders

New approach for delivering vaccines and for stimulating body's immune system to attack tumors

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Scientists discover link between ageing process and hormone released from muscle after exercise

Blood pressure effects unclear in long-term stroke survivors

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Researchers identify new type of regulatory blood cells that can combat brain inflammation

New research points to potential target for treating triple negative breast cancer

Researchers use new technique that can partially move tumors from inoperable locations in brain

Highlights: N.D. hospital and abortion docs; Calif. sugary beverage bill; aging home care workers in Texas

Study explains clinical, public health challenges for use of statins in treatment of heart attacks

Vitamin C may reduce risk of most common type of hemorrhagic stroke, says study

Extreme loneliness can increase premature death by 14% in older adults

Discovery opens door for more targeted treatments for cancer patients

Research provides new insight into the effect of misfolded proteins in neurodegenerative disorders

Mobile compression device just as effective as blood thinners in preventing DVT after joint surgery

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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