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Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found a chemical "signature" in blood-forming stem cells that predicts whether patients with acute myeloid leukemia (AML) will respond to chemotherapy.

4 Feb 2014

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

An initiative is under way to develop new drugs for a devastating tropical disease that threatens almost 70 million people in Africa.

4 Feb 2014

Sanford Hospital starts clinical trial to study dissolving device in patients with CAD

Sanford Heart Hospital has started a clinical trial to study a dissolving device in patients with coronary artery disease. The ABSORB III clinical trial will investigate the safety and effectiveness of the Absorb Bioresorbable Vascular Scaffold (BVS) device, manufactured by global health care company Abbott.

4 Feb 2014

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE - angiotensin-converting enzyme - a naturally occurring protein found in tissues throughout the body.

4 Feb 2014

Blood pressure lowering linked with reduced risk for cognitive decline in patients with T2DM

Intensive blood pressure and cholesterol lowering was not associated with reduced risk for diabetes-related cognitive decline in older patients with long-standing type 2 diabetes mellitus, according to a study by Jeff D. Williamson, M.D., M.H.S., of the Wake Forest School of Medicine, Winston-Salem, N.C., and colleagues.

4 Feb 2014

Children who received radiation as part of treatment may have lower long-term survival rates, says study

The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that few die from the tumor as adults.

4 Feb 2014

Surgeons report safer method to replace bone removed from skull after lifesaving brain surgery

Johns Hopkins surgeons report they have devised a better, safer method to replace bone removed from the skull after lifesaving brain surgery. The new technique, they say, appears to result in fewer complications than standard restoration, which has changed little since its development in the 1890s.

4 Feb 2014

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

Treating depression before onset of cardiovascular disease can cut risk of heart attack, stroke

Research led by Jesse C. Stewart, Ph.D., of the School of Science at Indiana University-Purdue University Indianapolis, is the first to find that treatment of depression before any apparent signs of cardiovascular disease can decrease the risk of future heart attacks and strokes by almost half.

4 Feb 2014

Nearly half of HIV-infected teenagers, young adults forego treatment

Nearly half of HIV-infected teenagers and young adults forego timely treatment, delaying care until their disease has advanced, which puts them at risk for dangerous infections and long-term complications, according to a study led by the Johns Hopkins Children's Center.

4 Feb 2014

High sodium intake correlates with fatness and inflammation in adolescents

Most adolescents consume as much salt as adults - some more than twice the recommended daily allowance - and that high sodium intake correlates with fatness and inflammation regardless of how many calories they consume, researchers report.

3 Feb 2014

Incontinence prophylaxis shows potential in pelvic organ prolapse

Research from Taiwan suggests that combining trocar-guided transvaginal mesh surgery with a midurethral sling in the treatment of women with advanced pelvic organ prolapse could be an effective way to manage associated stress urinary incontinence.

3 Feb 2014

Morning blood pressure tied to target-organ damage

Physicians should ask patients to take home blood pressure readings in the morning as well as the evening before making therapeutic decisions, say researchers.

3 Feb 2014

Putnam Hospital Center recognized with CEO Cancer Gold Standard accreditation

Putnam Hospital Center in Carmel, NY, is leading by example when it comes to promoting healthy lifestyle choices and encouraging workplace wellness. The CEO Roundtable on Cancer has accredited Putnam Hospital Center with the CEO Cancer Gold Standard recognizing the firm's efforts to reduce the risk of cancer for its employees and covered family members by establishing programs to reduce cancer risk, encouraging early detection through cancer screenings, and ensuring access to quality treatment.

3 Feb 2014

FDA grants Breakthrough Therapy designation to GSK's Promacta/Revolade for treatment of cytopenias

Ligand Pharmaceuticals Incorporated today announced that the U.S. Food and Drug Administration has granted its partner GlaxoSmithKline plc Breakthrough Therapy designation for Promacta/Revolade (eltrombopag) for the treatment of cytopenias in patients with severe aplastic anemia (SAA) who have had insufficient response to immunosuppressive therapy.

3 Feb 2014

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Antibiotic resistance is a consequence of antibiotic use. Bacteria adapt to the threat of antibiotics using mechanisms to overcome the drug. These bacteria, which we call resistant bacteria, then survive.

3 Feb 2014

Five important numbers to keep cardiovascular system healthy

Pass codes, phone numbers, social security numbers, clothing sizes and addresses. We all have a lot of numbers in our heads, but heart experts at The Ohio State University Wexner Medical Center say there are five more you need to know to help keep your cardiovascular system healthy.

3 Feb 2014

African American youths who experienced discrimination during adolescence may develop chronic diseases

African American youth who report experiencing frequent discrimination during adolescence are at risk for developing heart disease, high blood pressure, diabetes, and stroke in later years, according to a new study.

3 Feb 2014

'Spontaneous' changes in immune cells on a daily basis may lead to cancers, says study

Immune cells undergo 'spontaneous' changes on a daily basis that could lead to cancers if not for the diligent surveillance of our immune system, Melbourne scientists have found.

3 Feb 2014

Researchers identify protein critical to hematopoietic stem cell function, blood formation

Researchers at the University of California, San Diego School of Medicine have identified a protein critical to hematopoietic stem cell function and blood formation. The finding has potential as a new target for treating leukemia because cancer stem cells rely upon the same protein to regulate and sustain their growth.

3 Feb 2014

Blood News and Research

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

Sanford Hospital starts clinical trial to study dissolving device in patients with CAD

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Blood pressure lowering linked with reduced risk for cognitive decline in patients with T2DM

Children who received radiation as part of treatment may have lower long-term survival rates, says study

Surgeons report safer method to replace bone removed from skull after lifesaving brain surgery

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

Treating depression before onset of cardiovascular disease can cut risk of heart attack, stroke

Nearly half of HIV-infected teenagers, young adults forego treatment

High sodium intake correlates with fatness and inflammation in adolescents

Incontinence prophylaxis shows potential in pelvic organ prolapse

Morning blood pressure tied to target-organ damage

Putnam Hospital Center recognized with CEO Cancer Gold Standard accreditation

FDA grants Breakthrough Therapy designation to GSK's Promacta/Revolade for treatment of cytopenias

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Five important numbers to keep cardiovascular system healthy

African American youths who experienced discrimination during adolescence may develop chronic diseases

'Spontaneous' changes in immune cells on a daily basis may lead to cancers, says study

Researchers identify protein critical to hematopoietic stem cell function, blood formation

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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