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Treating peanut allergy with oral immunotherapy changes DNA of immune cells

Treating a peanut allergy with oral immunotherapy changes the DNA of the patient's immune cells, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford. The DNA change could serve as the basis for a simple blood test to monitor the long-term effectiveness of the allergy therapy.

31 Jan 2014

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression.

31 Jan 2014

New study reveals way to combat drug-resistant tumors

Cancer drugs that recruit antibodies from the body's own immune system to help kill tumors have shown much promise in treating several types of cancer. However, after initial success, the tumors often return.

31 Jan 2014

Study describes new tack in treatment of lung adenocarcinomas

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

31 Jan 2014

Drugs that modify DNA structure may be beneficial for treating Alzheimer's disease

In a study published this week in Nature Neuroscience, Bess Frost, PhD, and co-authors, identify abnormal expression of genes, resulting from DNA relaxation, that can be detected in the brain and blood of Alzheimer's patients.

31 Jan 2014

Beaumont Health System use new balloon ablation technology to treat atrial fibrillation

Beaumont Health System is the first center outside of Japan to use a new balloon ablation technology to treat atrial fibrillation, the most common heart rhythm disorder that affects about 3 million people in the U.S.

31 Jan 2014

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

Boehringer Ingelheim Pharmaceuticals, Inc. and Duke Clinical Research Institute have formed a unique collaborative relationship to uncover insights into idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease.

31 Jan 2014

Researchers find no benefit in replacing fructose with glucose

Researchers at St. Michael's Hospital have found there is no benefit in replacing fructose, the sugar most commonly blamed for obesity, with glucose in commercially prepared foods.

31 Jan 2014

Prediction models can be useful for heart team to determine best treatment strategy

Detailed prediction models that project long-term patient mortality following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) surgery can be useful for the heart team when determining the best treatment strategy for individual patients, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

31 Jan 2014

Clonidine before surgery may control post-surgical pain and child's anxiety

Managing a child's pain and distress after surgery is an essential part of recovery. However, using strong painkilling medications post-surgery can put kids at risk for side effects and other complications.

31 Jan 2014

Look to heart shaped foods to protect heart

The crumbs from the Christmas cookies are gone and black-eyed peas, eaten on New Year to bring luck, are a distant memory. Declared American Heart Month with Valentine's Day smack dab in the middle, February is here. What to eat to keep your heart healthy?

31 Jan 2014

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

The Nairobi-based International Livestock Research Institute announced today that a global consortium supported by the Bill & Melinda Gates Foundation has been formed to develop a new vaccine against a disease that's devastating cattle herds in sub-Saharan Africa. This highly advanced cattle vaccine project could also help malaria and cancer research in humans.

31 Jan 2014

Psychiatrists urged to monitor metabolic changes in psychosis patients

Japanese psychiatrists are largely aware of the metabolic abnormalities that may arise from antipsychotic treatment, but most do not monitor their patients sufficiently, research shows.

30 Jan 2014

Checklists and feedback for ambulance crews improve care for heart attack and stroke patients

The introduction of checklists and better feedback for ambulance crews as part of a national quality improvement project has significantly improved the standard of care for heart attack and stroke patients across England, a major new study has shown.

30 Jan 2014

Nanomix announces closure of private financing for $12M

Nanomix Inc., (Nanomix), a leading nanotechnology company focused on development of next generation Point of Care diagnostic tests to enable earlier and more accurate testing in hospital and pre-hospital settings, today announced that is has closed private financing for approximately $12 million.

30 Jan 2014

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

Alexion Pharmaceuticals, Inc. today announced financial results for the quarter and year ended December 31, 2013. For the three months ended December 31, 2013, Alexion Pharmaceuticals, Inc. ("Alexion" or the "Company") reported net product sales of Soliris® (eculizumab) of $441.9 million, compared to $320.5 million for the same period in 2012.

30 Jan 2014

New molecule could help lower diabetic patients' risk of developing dementia or Alzheimer's

Researchers at the Hebrew university of Jerusalem have created a molecule that could potentially lower diabetic patients' higher risk of developing dementia or Alzheimer's disease.

30 Jan 2014

Geranium plant extracts prevent HIV-1 from invading human cells

Extracts of the geranium plant Pelargonium sidoides inactivate human immunodeficiency virus type 1 (HIV-1) and prevent the virus from invading human cells. In the current issue of "PLOS ONE", scientists from the Helmholtz Zentrum München report that these extracts represent a potential new class of anti-HIV-1 agents for the treatment of AIDS.

30 Jan 2014

CTI announces initiation of pacritinib Phase 2 trial in AML patients with FLT3 mutations

Cell Therapeutics, Inc. today announced the initiation of an international cooperative group Phase 2 clinical trial of pacritinib in adult patients with relapsed acute myeloid leukemia (AML) with mutations of the FLT3 gene. Mutation of the FLT3 gene is found in approximately one-third of AML patients and is an independent risk factor for poor prognosis.

30 Jan 2014

Researchers engineer skin cells for first time containing blood and lymphatic capillaries

Researchers at the University Children's Hospital Zurich and the University of Zurich have engineered skin cells for the very first time containing blood and lymphatic capillaries. They succeeded in isolating all the necessary types of skin cells from human skin tissue and engineering a skin graft that is similar to full-thickness skin.

30 Jan 2014

Blood News and Research

Treating peanut allergy with oral immunotherapy changes DNA of immune cells

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

New study reveals way to combat drug-resistant tumors

Study describes new tack in treatment of lung adenocarcinomas

Drugs that modify DNA structure may be beneficial for treating Alzheimer's disease

Beaumont Health System use new balloon ablation technology to treat atrial fibrillation

Boehringer Ingelheim, DCRI partner to uncover insights into idiopathic pulmonary fibrosis

Researchers find no benefit in replacing fructose with glucose

Prediction models can be useful for heart team to determine best treatment strategy

Clonidine before surgery may control post-surgical pain and child's anxiety

Look to heart shaped foods to protect heart

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

Psychiatrists urged to monitor metabolic changes in psychosis patients

Checklists and feedback for ambulance crews improve care for heart attack and stroke patients

Nanomix announces closure of private financing for $12M

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

New molecule could help lower diabetic patients' risk of developing dementia or Alzheimer's

Geranium plant extracts prevent HIV-1 from invading human cells

CTI announces initiation of pacritinib Phase 2 trial in AML patients with FLT3 mutations

Researchers engineer skin cells for first time containing blood and lymphatic capillaries

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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