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Opinions: Africans fight malaria; Access to AIDS treatment; Noncommunicable disease summit; Maternal, child health efforts

In an East African opinion piece, U.N. Special Envoy for Malaria Ray Chambers; Mark Green, the director of the Malaria No More Policy Center; and John Bridgeland, vice chairman of Malaria No More, highlight Africans' involvement in addressing malaria on the continent.

15 May 2010

Science special issue reports on Malaria

This week's issue of Science features news articles focusing on recent progress on malaria control in Africa and discussing future challenges, including drug resistance.

15 May 2010

Lotus Pharmaceuticals first-quarter net income up 38%

Lotus Pharmaceuticals, Inc., a growing developer, manufacturer and seller of medicine and drugs in the People's Republic of China today reported its financial results for the first quarter ended March 31, 2010.

15 May 2010

Recent releases in Global Health

As the 193 WHO member states gather at next week's World Health Assembly (WHA) "a draft global code of practice on the international recruitment of health personnel will be on the agenda. Negotiation and adoption of a WHO code of practice is an unprecedented opportunity to advance global consensus to address the critical challenges of migration of health workers and its effect on health systems worldwide," the authors of a Lancet Comment write.

15 May 2010

Oxygen levels induce X chromosome inactivation in female cells: Study

Oxygen levels in the lab can permanently alter human embryonic stem (ES) cells, specifically inducing X chromosome inactivation in female cells, according to Whitehead Institute researchers. Human ES cells have been routinely created and maintained at atmospheric levels of oxygen, which is about 20%. Cells in the body are usually exposed to only 1-9% oxygen.

14 May 2010

Scientists look for new ways to fight TB

Scientists looking for new ways to fight tuberculosis have their sights set on a structure essential to the bacterium's survival. Disabling this structure could kill the microbes in the infected host and thwart TB infections. In a study appearing online May 11, 2010, in EMBO J, the journal of the European Molecular Biology Organization, scientists from the U.S. Department of Energy's Brookhaven National Laboratory, Stony Brook University, and Weill Cornell Medical College describe new features of how this structure, known as a proteasome, is put together and how it works.

14 May 2010

SQI announces poster presentations on novel diagnostic assays at 7th International Congress on Autoimmunity

SQI Diagnostics Inc., a medical systems automation company focused on evolving laboratory-based biomarker testing, today announced data from oral and poster presentations that highlights the Company's leadership position in the autoimmune diagnostics space.

14 May 2010

New way to coax embryonic stem cells and reprogrammed adult cells to develop sensory cells

After ten years of effort, researchers reporting in the May 14th issue of the journal Cell, a Cell Press publication, say they have found a way to coax embryonic stem cells as well as reprogrammed adult cells to develop into sensory cells that normally reside in the mammalian inner ear. Those mechanosensitive sensory hair cells are the linchpin of hearing and balance.

14 May 2010

Poorly designed clinical trials adversely affect medical advances

In a paper published this week in Science, experts caution that important ethical issues in the testing of new therapies like stem cells may not be receiving the attention they deserve. Carnegie Mellon University's Dr. Alex John London (Dept. of Philosophy) joined McGill University's Dr. Jonathan Kimmelman (Faculty of Medicine) and University of Wisconsin-Madison's Marina Emborg (Dept. of Medical Physics) to examine the way scientists, physicians, and regulators evaluate risk and benefit when testing new drugs in human beings for the first time.

14 May 2010

NanoViricides signs research and development agreement with Dr. Ken S. Rosenthal's laboratory

NanoViricides, Inc., reports that it has signed a research and development agreement with Dr. Ken S. Rosenthal's laboratory at Northeastern Ohio Universities Colleges of Medicine and Pharmacy.

14 May 2010

Off-label use of AAs among elderly associated with increased risk of diabetes: Study

A new study yields important new evidence that the use of atypical antipsychotics among the elderly for off-label purposes is associated with increased risk of developing diabetes.

14 May 2010

Stanford researchers make hair-cell-like cells in a petri dish

Deep inside the ear, specialized cells called hair cells detect vibrations in the air and translate them into sound. Ten years ago, Stefan Heller, PhD, professor of otolaryngology at the Stanford University School of Medicine, came up with the idea that if you could create these cells in the laboratory from stem cells, it would go a long way toward helping scientists understand the molecular basis of hearing in order to develop better treatments for deafness.

14 May 2010

EPA continues to validate ToxCast screening tool by testing more than 100 drugs

The U.S. Environmental Protection Agency will continue validating its ToxCast screening tool by screening more than 100 drugs provided by Pfizer, GlaxoSmithKline, Sanofi-Aventis, and Merck. These drugs never entered the marketplace because they demonstrated different types and levels of toxicity when the pharmaceutical companies conducted the early stage clinical trials required by the Food and Drug Administration as part of the drug development process.

14 May 2010

Prometheus announces novel method for early detection of HACA during infliximab treatment

Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced a new method for detecting antibody levels in individual patients treated with infliximab, a biologic therapy that has been used to treat more than a million patients across a number of autoimmune diseases, including rheumatoid arthritis, Crohn's disease and ulcerative colitis.

14 May 2010

India, Brazil launch trade dispute against EU, Netherlands over seizures of generic drugs

"India and Brazil launched a trade dispute against the European Union and the Netherlands on Wednesday, saying their seizures of generic drugs were hurting healthcare in poor countries and disrupting international trade," Reuters reports.

14 May 2010

Increase in use of imaging scans underscores need for evidence-based protocols in cancer care

New research showing a more than 30 percent annual increase in the use of high-tech imaging scans in older cancer patients underscores the need for evidence-based protocols in cancer care, said MedSolutions, a leading provider of medical management services.

14 May 2010

MitoSciences awarded $590,000 to support development of companion diagnostic tests for antiviral drugs

MitoSciences announces that it has just been awarded $590,000 by the National Institutes of Health to support the development of companion diagnostic tests for antiviral drugs. The award was made after competitive scientific review and was issued under The American Recovery and Reinvestment Act of 2009.

14 May 2010

New Infrared Relief therapy now available for patients with diabetic neuropathies

Genesis Spine Associates now offers Infrared Relief - a new, highly effective pain management therapy using infrared light for patients suffering from diabetic neuropathies. This new therapy offers a simple, painless option for managing patients' pain without potentially dangerous drugs or surgery.

14 May 2010

Chimerix commences first-in-human study of CMX157 for HIV

Chimerix, Inc., a biotechnology company developing orally-available antiviral therapeutics, announced the commencement of a first-in-human study of CMX157, a novel lipid conjugate of the nucleotide tenofovir with in vitro activity against both tenofovir-sensitive and tenofovir-resistant human immunodeficiency virus (HIV). CMX157 has the potential to increase efficacy and decrease toxicity as compared to tenofovir, and may enable the creation of new 'one pill, once-a-day', fixed-dose combination regimens for the treatment of HIV infection.

14 May 2010

CyGene Laboratories reports heightened interest in at-home genetic testing

CyGene Laboratories Inc. today announced that it has experienced unprecedented levels of interest and requests for information following recent media coverage of Walgreens' decision to offer genetics testing kits supplied by Pathway Genomics in certain of their retail stores.

13 May 2010

Drugs News and Research

Opinions: Africans fight malaria; Access to AIDS treatment; Noncommunicable disease summit; Maternal, child health efforts

Science special issue reports on Malaria

Lotus Pharmaceuticals first-quarter net income up 38%

Recent releases in Global Health

Oxygen levels induce X chromosome inactivation in female cells: Study

Scientists look for new ways to fight TB

SQI announces poster presentations on novel diagnostic assays at 7th International Congress on Autoimmunity

New way to coax embryonic stem cells and reprogrammed adult cells to develop sensory cells

Poorly designed clinical trials adversely affect medical advances

NanoViricides signs research and development agreement with Dr. Ken S. Rosenthal's laboratory

Off-label use of AAs among elderly associated with increased risk of diabetes: Study

Stanford researchers make hair-cell-like cells in a petri dish

EPA continues to validate ToxCast screening tool by testing more than 100 drugs

Prometheus announces novel method for early detection of HACA during infliximab treatment

India, Brazil launch trade dispute against EU, Netherlands over seizures of generic drugs

Increase in use of imaging scans underscores need for evidence-based protocols in cancer care

MitoSciences awarded $590,000 to support development of companion diagnostic tests for antiviral drugs

New Infrared Relief therapy now available for patients with diabetic neuropathies

Chimerix commences first-in-human study of CMX157 for HIV

CyGene Laboratories reports heightened interest in at-home genetic testing

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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