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PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

Researchers at University of California, San Diego School of Medicine report a three-fold increase in the use of minimally invasive surgery across the nation for patients with pancreatic disease. Although adaptation of MIS for this difficult-to-reach gland is recent, the growing trend points to improved patient outcomes, such as reduced bleeding and infections. Now published online, the paper will appear in the March print edition of JAMA Surgery.

15 Jan 2014

First commercial implant of Elixir's DESolve Novolimus Eluting Coronary Scaffold performed in Germany

Marking a milestone in the evolution of fully-bioresorbable drug-eluting scaffolds for interventional cardiology, the first commercial implant of Elixir Medical's CE Mark-approved DESolve Novolimus Eluting Coronary Scaffold was performed in Germany by Professor Dr. med. Holger Nef, Head of the Cardiac Catheterization Laboratory, University Hospital Giessen, Giessen, Germany.

15 Jan 2014

FDA accepts Iroko Pharmaceuticals' ZORVOLEX sNDA for review

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, announced that the U.S. Food and Drug Administration has accepted for review the Supplemental New Drug Application for ZORVOLEX (diclofenac), a lower dose nonsteroidal anti-inflammatory drug, for the proposed indication of treatment of osteoarthritis pain in adults. ZORVOLEX was approved by FDA in October 2013 for the treatment of mild to moderate acute pain in adults.

15 Jan 2014

Research findings provide insights into risks associated with isolated mild hyperglycemia

Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the gene encoding the enzyme glucokinase had a low prevalence of clinically significant vascular complications, findings that provide insights into the risks associated with isolated mild hyperglycemia, according to a study in the January 15 issue of JAMA.

15 Jan 2014

New stem cell study explains how breast cancer spreads

Breast cancer stem cells exist in two different states and each state plays a role in how cancer spreads, according to an international collaboration of researchers. Their finding sheds new light on the process that makes cancer a deadly disease.

15 Jan 2014

BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

15 Jan 2014

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

Treatment and "cure" of breast cancer doesn't ensure that the disease won't spread to the brain. Too often, sometimes years after an initial diagnosis and remission, breast cancer cells are discovered growing as new tumors within the brain. Now City of Hope researchers have found how this happens.

15 Jan 2014

New minimally invasive procedure for AF patients who are intolerant of blood-thinning medications

Sanford Heart Hospitals in Fargo and Sioux Falls now provide a new, minimally invasive procedure for atrial fibrillation (AF) patients who are intolerant of blood-thinning medications. Atrial fibrillation is a heart disorder that affects nearly 3 million adults in the United States.

15 Jan 2014

Hepatitis C infection varies widely among different Hispanic groups in the U.S.

The first study of hepatitis C infection among different Hispanic groups in the U.S. has found that infection with the virus varies widely, with Puerto Rican Hispanics much more likely than other groups to be infected. The study, led by researchers at Albert Einstein College of Medicine of Yeshiva University, highlights which Hispanic populations would benefit most from increased hepatitis C testing and treatment.

15 Jan 2014

Research paper highlights the role of T-cells in HIV

Ryan Zurakowski, assistant professor of electrical and computer engineering at the University of Delaware, is co-author of a paper appearing in Nature Medicine on Jan. 12 highlighting the role of T-cells in HIV.

15 Jan 2014

Idiopathic pulmonary fibrosis (IPF) and herpesvirus saimiri: an interview with Elazar Rabbani, Chief Executive Officer of Enzo

Pulmonary fibrosis is a condition where fibrotic or scarred tissue progressively develops in the lungs. In some cases the particular cause is known but in others it remains unknown and is given the term “idiopathic”.

14 Jan 2014

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

13 Jan 2014

Study shows that high-blood pressure medicine may also prevent migraines

Candesartan is just as effective as more the commonly prescribed propranolol when it comes to preventing migraine attacks, according to a new study from St. Olavs Hospital in Trondheim, Norway and the Norwegian University of Science and Technology (NTNU).

13 Jan 2014

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

AstraZeneca and Bristol-Myers Squibb Company announced the U.S. Food and Drug Administration approved Farxiga™ [far-SEE-ga] (dapagliflozin), a once-daily oral treatment indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

13 Jan 2014

Cord blood vitamin D linked to pediatric RTI risk

South Korean researchers say that encouraging pregnant women to spend more time outdoors or to increase their vitamin D supplementation may reduce the number of respiratory tract infections in their infants.

13 Jan 2014

Obesity interferes with blood pressure control

Patients who are overweight or obese have a high risk for uncontrolled blood pressure, despite often taking multiple antihypertensive agents, say researchers.

13 Jan 2014

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.

13 Jan 2014

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Researchers at the University of Massachusetts Medical School (UMMS) have been commissioned by the Alpha-1 Project (TAP) to develop a PiZ antibody. The antibody will be used to track the presence of mutant alpha-1 PiZ protein in human blood serum, an essential tool in testing potential therapies for Alpha-1 Antitrypsin Deficiency (Alpha-1).

13 Jan 2014

Scientists discover genetic signature mechanism in immune system as driving force for childhood leukaemia

Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia.

13 Jan 2014

Blood News and Research

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

First commercial implant of Elixir's DESolve Novolimus Eluting Coronary Scaffold performed in Germany

FDA accepts Iroko Pharmaceuticals' ZORVOLEX sNDA for review

Research findings provide insights into risks associated with isolated mild hyperglycemia

New stem cell study explains how breast cancer spreads

BMH-21 chemical compound has ability to shut down a common cancer process

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

New minimally invasive procedure for AF patients who are intolerant of blood-thinning medications

Hepatitis C infection varies widely among different Hispanic groups in the U.S.

Research paper highlights the role of T-cells in HIV

Idiopathic pulmonary fibrosis (IPF) and herpesvirus saimiri: an interview with Elazar Rabbani, Chief Executive Officer of Enzo

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

Study shows that high-blood pressure medicine may also prevent migraines

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

Cord blood vitamin D linked to pediatric RTI risk

Obesity interferes with blood pressure control

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Scientists discover genetic signature mechanism in immune system as driving force for childhood leukaemia

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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