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Cardiovascular conditions may be overlooked in bipolar disorder

Cardiovascular comorbidities may be going under-recognized and undertreated in patients with bipolar disorder, say UK researchers.

10 Jan 2014

Researchers develop automated venipuncture device that automates phlebotomy procedure

A new medical device has been developed that will provide phlebotomists and clinicians with a technology to enable blood drawing accuracy at first stick. This is particularly important considering the diverse patient demographic each with various levels of difficult venous access.

10 Jan 2014

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

Producing brightly speckled red and green snapshots of many different tissues, Johns Hopkins researchers have color-coded cells in female mice to display which of their two X chromosomes has been made inactive, or “silenced.”

10 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

[The] problem with the Affordable Care Act isn't the insurance industry. In fact, the main benefits of nationalized health care can be achieved in systems with hundreds, even thousands, of for-profit insurers. ...

10 Jan 2014

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

A team including University of North Carolina and NIH scientists has demonstrated in a mouse model that an HIV-specific poison can kill cells in which the virus is actively reproducing despite antiretroviral therapy.

10 Jan 2014

Synta initiates three multicenter trials to evaluate ganetespib with chemotherapy for AML and MDS

Synta Pharmaceuticals Corp. today announced the initiation of three multicenter, randomized trials supported by the Leukemia & Lymphoma Research Fund and Cancer Research UK, evaluating ganetespib in combination with chemotherapy in first-line treatment of patients with AML and high risk MDS.

10 Jan 2014

Biologists discover new pathway for repairing nerve cells

Penn State University molecular biologists have discovered a brand-new pathway for repairing nerve cells that could have implications for faster and improved healing. The researchers describe their findings in a paper titled "Dendrite injury triggers DLK-independent regeneration," which will be published in the 30 January 2014 issue of the journal Cell Reports.

10 Jan 2014

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types, transforming - among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself.

10 Jan 2014

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

T2 Biosystems, a company developing direct detection products enabling superior diagnostics, announced that scientists from the University of Pennsylvania and T2 Biosystems have published a paper in Blood describing novel clot structure biology detected while testing T2 Bio's T2HemoStat-.

10 Jan 2014

New study gives hope for novel glioblastoma multiforme treatment

A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.

9 Jan 2014

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.

9 Jan 2014

Study provides details to help scientists design better vaccines for Plasmodium vivax

A form of malaria common in India, Southeast Asia and South America attacks human red blood cells by clamping down on the cells with a pair of proteins, new research at Washington University School of Medicine in St. Louis has revealed.

9 Jan 2014

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The Scripps Research Institute.

9 Jan 2014

New study compares blood pressure management in the US and England

In the US but not in England, patients on low incomes with high blood pressure have their condition managed poorly compared with those who earn more.

9 Jan 2014

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Trevena, Inc., a clinical stage pharmaceutical company involved in the discovery and development of G-protein coupled receptor biased ligands, announced today initiation of dosing in BLAST-AHF, the Company's randomized, multi-center Phase 2b trial of TRV027 in patients with acute heart failure.

9 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

Monitoring air pollution now possible with technological advances in air quality measurement methods

Launching a natural research experiment in Kathmandu, Nepal, this month using advanced monitoring methods to assess health risk from air pollution, environmental health scientist Rick Peltier at the University of Massachusetts Amherst hopes to demonstrate for the first time in a real-world setting that air pollution can and should be regulated based on toxicology variables rather than simply on the volume of particles in the air.

9 Jan 2014

High aerobic fitness in late adolescence may reduce heart attack risk later in life

Researchers in Sweden have found an association between a person’s fitness as a teenager and their risk of heart attack in later life. In a study of nearly 750,000 men, they found that the more aerobically fit men were in late adolescence, the less likely they were to have a heart attack 30 or 40 years later.

9 Jan 2014

Blood News and Research

Cardiovascular conditions may be overlooked in bipolar disorder

Researchers develop automated venipuncture device that automates phlebotomy procedure

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

Synta initiates three multicenter trials to evaluate ganetespib with chemotherapy for AML and MDS

Biologists discover new pathway for repairing nerve cells

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

New study gives hope for novel glioblastoma multiforme treatment

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

Study provides details to help scientists design better vaccines for Plasmodium vivax

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

New study compares blood pressure management in the US and England

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Monitoring air pollution now possible with technological advances in air quality measurement methods

High aerobic fitness in late adolescence may reduce heart attack risk later in life

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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