Genetic News and Research

RSS

CBL identified as the most promising potential biomarker for aortic dissection

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection (AD) is a fatal cardiovascular disease for which the key involved genes are largely unknown.

29 Aug 2024

New bacterial defense mechanism revealed as potential tool for genome editing

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

29 Aug 2024

Low lipoprotein (a) levels do not cause type 2 diabetes, research shows

New research has shown that, contrary to some previous studies, low levels of lipoprotein (a) – a parcel of fats and protein in the blood – do not cause type 2 diabetes.

29 Aug 2024

Studies uncover mechanisms behind micronuclear instability and cancer progression

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) often observed in aggressive tumor behavior.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

New insights into AD pathogenesis and treatment

The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.

29 Aug 2024

Study reveals the role of blood clotting in COVID-19

In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while also suppressing the body's ability to clear the virus.

29 Aug 2024

New system can spot genetic markers of autism in brain images with high accuracy

A multi-university research team co-led by University of Virginia engineering professor Gustavo K. Rohde has developed a system that can spot genetic markers of autism in brain images with 89 to 95% accuracy.

28 Aug 2024

Study reveals a new target for universal treatment for autoimmune diseases

More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an underlying cause of autoimmune disease, specifically multiple sclerosis (MS).

28 Aug 2024

Study reveals how bacteria pass on traits without DNA changes

Bacterial cells can "remember" brief, temporary changes to their bodies and immediate surroundings, a new Northwestern University and University of Texas-Southwestern study has found.

28 Aug 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

Hereditary cardiac amyloidosis more common in the UK than previously thought

More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, according to a new study led by researchers at UCL (University College London) and Queen Mary University of London.

28 Aug 2024

Research highlights potential of blood epigenetics for dementia risk assessment

New research suggests that epigenetic markers in the blood could be useful for understanding dementia risk.

28 Aug 2024

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Study reveals increasing influence of non-cognitive skills on academic achievement from childhood to adolescence

The study highlights the genetic basis of non-cognitive skills and their impact on academic performance, suggesting strategies for educational improvement.

28 Aug 2024

New study develops enhanced mortality prediction model for COPD patients

Innovative probabilistic graph models identify unique factors linked to COPD mortality, paving the way for targeted interventions and improved patient outcomes.

28 Aug 2024

A study confirms that smoking significantly increases the risk of stroke

Findings indicate smoking elevates stroke risk, particularly in older males with comorbidities, underscoring the need for targeted prevention strategies.

28 Aug 2024

Study identifies genetic cause of severe seizures in children

Shortly after Kelly Cervantes' daughter Adelaide was born, she started having terrible seizures. Doctors were unable to give her a solution, or even a cause.

28 Aug 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

CNRS scientists uncover activation mechanism of bemnifosbuvir

CNRS Scientists have deciphered the activation pathway of bemnifosbuvir, a drug candidate initially in development to treat hepatitis C virus (HCV). The findings of the research team, led by CNRS scientists, unlock new opportunities to boost the efficacy of this type of drug against other RNA viruses, such as the ones that cause Covid-19 and dengue fever.

28 Aug 2024