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Does stress damage the brain?

In the March 1st issue of Biological Psychiatry, published by Elsevier, a paper by Tibor Hajszan and colleagues provides an important new chapter to this question.

16 Mar 2009

Potential pathway for drug intervention

A newly identified molecular pathway that directs stem cells to produce glial cells yields insights into the neurobiology of Down's syndrome and a number of central nervous system disorders characterized by too many glial cells, according to a recent study by researchers at the Salk Institute for Biological Studies.

15 Mar 2009

Discovery of master regulator of motor neuron firing

When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation.

15 Mar 2009

Parkinson's-linked mutation makes neurons vulnerable to calcium-induced death

A new study reveals the mechanism by which a genetic mutation linked with Parkinson's disease (PD) renders dopamine neurons particularly vulnerable to cell injury and death.

12 Mar 2009

Researchers show how the hippocampus records memory

It may be possible to "read" a person's memories just by looking at brain activity, according to research carried out by Wellcome Trust scientists.

12 Mar 2009

A blood test for Alzheimer's on the horizon

Researchers have revealed a direct relationship between two specific antibodies and the severity of Alzheimer's disease symptoms, raising hopes that a diagnostic blood test for the devastating disorder is within reach.

11 Mar 2009

A nanotech coating for brain implants

Biomedical and materials engineers at the University of Michigan have developed a nanotech coating for brain implants that helps the devices operate longer and could improve treatment for deafness, paralysis, blindness, epilepsy and Parkinson's disease.

11 Mar 2009

New perspective on what part of the brain controls fear

Mice lose their fear of territorial rivals when a tiny piece of their brain is neutralized, a new study reports.

10 Mar 2009

Diabetes and elevated levels of cholesterol linked to faster cognitive decline in Alzheimer's patients

A history of diabetes and elevated levels of cholesterol, especially LDL cholesterol, are associated with faster cognitive decline in patients with Alzheimer's disease, according to a new study from Columbia University Medical Center researchers.

10 Mar 2009

Diabetes and elevated levels of cholesterol linked to cognitive decline in Alzheimer's

10 Mar 2009

Breakthrough method produces Parkinson's disease patient-specific stem cells free of harmful reprogramming genes

Whitehead Institute researchers have developed a novel method to remove potential cancer-causing genes during the reprogramming of skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

8 Mar 2009

Virus-free embryonic-like stem cells made from skin of Parkinson's disease patients

Researchers reporting in the March 6th issue of the journal Cell , a Cell Press publication, have developed a new way to produce human embryonic-like stem cells that are free of the viruses used to insert the key ingredients.

5 Mar 2009

Discovery of new gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH), MIT, the Broad Institute, King's College London (KCL) and other institutions has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

5 Mar 2009

Breakthrough produces Parkinson's patient-specific stem cells free of harmful reprogramming genes

Deploying a method that removes potentially cancer-causing genes, Whitehead Institute researchers have "reprogrammed" human skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

5 Mar 2009

Experts discuss factors that may contribute to glaucoma

Although scientists know progressive degeneration of retinal ganglion cells and their axons is the primary cause of glaucoma, researchers have yet to identify a way to stop or prevent the degeneration.

4 Mar 2009

Study sheds light on underlying neural mechanism behind macular degeneration

In macular degeneration, the most common form of adult blindness, patients progressively lose vision in the center of their visual field, thereby depriving the corresponding part of the visual cortex of input.

3 Mar 2009

New clues about mitochondrial 'growth spurts'

Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation are also part of the equation.

2 Mar 2009

New mechanistic explanation of how the brain interprets stress signals

Chronic stress takes a physical and emotional toll on our bodies and scientists are working on piecing together a medical puzzle to understand how we respond to stress at the cellular level in the brain.

2 Mar 2009

Deciphering motor neuron disease

Dr Ian Blair and Professor Garth Nicholson from the University of Sydney's ANZAC Research Institute have identified a new gene abnormality that causes the fatal paralysis, motor neuron disease (MND) in families with multiple members affected by the disease.

1 Mar 2009

Researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

26 Feb 2009