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New strategy may ensure safety of adult epidermal stem cells before performing treatments

A team of European researchers has devised a strategy to ensure that adult epidermal stem cells are safe before they are used as treatments for patients. The approach involves a clonal strategy where stem cells are collected and cultivated, genetically modified and single cells isolated before being rigorously tested to make sure they meet the highest possible safety criteria.

28 Feb 2015

New pharmacological compounds block nerve cell damage in mouse models of MS

A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

28 Feb 2015

TxCell invited to speak at largest US meeting for investors in emerging growth companies

In the presentation, Damian Marron will provide an overview of TxCell and its personalized T cell immunotherapy platform ASTrIA. Additional details will also be provided to institutional investors in one on one meetings at the conference.

27 Feb 2015

Feast-or-famine diet may extend lifespan, improve age-related diseases

University of Florida Health researchers have found that putting people on a feast-or-famine diet may mimic some of the benefits of fasting, and that adding antioxidant supplements may counteract those benefits.

27 Feb 2015

New test can predict survival chances of women with breast cancer

Scientists have developed a new test which can predict the survival chances of women with breast cancer by analysing images of 'hotspots' where there has been a fierce immune reaction to a tumour.

27 Feb 2015

New tool provides molecular details about how mutations affect cellular processes

Today in the journal Nature Methods, the laboratory headed by ICREA researcher Patrick Aloy, at the Institute for Research in Biomedicine, presents a computational tool that allows a greater understanding of the genetic causes of complex diseases such as cancer, Alzheimer's and diabetes.

27 Feb 2015

Life-saving bone marrow transplants are not available to all who need them

Bone marrow (hematopoietic stem cell) transplant is a life saving treatment for patients with blood cancer that replaces blood stem cells lost to disease or chemotherapy. However, for each patient to benefit a matching donor must be found to provide the stem cells for transplant.

27 Feb 2015

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Although essential marine omega-3 fatty acids and vitamin D have been shown to improve cognitive function and behavior in the context of certain brain disorders, the underlying mechanism has been unclear. In a new paper published in FASEB Journal by Rhonda Patrick, PhD and Bruce Ames, PhD of Children's Hospital Oakland Research Institute, serotonin is explained as the possible missing link tying together why vitamin D and marine omega-3 fatty acids might ameliorate the symptoms associated with a broad array of brain disorders.

27 Feb 2015

Pediatric patients who receive quick antibiotics for fever, neutropenia have reduced PICU needs

A University of Colorado Cancer Center study published in the journal Pediatric Blood & Cancer shows that pediatric cancer patients who receive antibiotics within 60 minutes of reporting fever and showing neutropenia (low neutrophil count), go on to have decreased intensive care consultation rate and lower mortality compared with patients who receive antibiotics outside the 60-minute window.

27 Feb 2015

Study finds correlation between tests for hemoglobin A1c using finger stick and oral blood

It is estimated that 8.1 million of the 29.1 million Americans living with diabetes are undiagnosed and many who have diabetes have poor glycemic control. Given that each year many Americans visit a dental provider but not a primary care provider, dental visits may be an opportune site for diabetes screening and monitoring glucose control for many at-risk patients.

27 Feb 2015

Study focuses on improving therapeutic outcomes in cancer patients through diet-drug combination

Boosting anti-cancer immunity through diet and novel drug therapies—that's the idea behind a collaborative project involving researchers from the South Dakota State University College of Pharmacy and Sanford Research in Sioux Falls.

27 Feb 2015

New research reveals that HIV latency is controlled by the virus itself

New research from the Gladstone Institutes for the first time provides strong evidence that HIV latency is controlled not by infected host cells, but by the virus itself. This fundamentally changes how scientists perceive latency, presenting it as an evolutionarily advantageous phenomenon rather than a biological accident.

27 Feb 2015

Study suggests benefits of calorie restriction on healthy aging

Targeting mechanisms in the central nervous system that sense energy generated by nutrients might yield the beneficial effects of low-calorie diets on healthy aging without the need to alter food intake, suggests new research from Harvard T.H. Chan School of Public Health.

27 Feb 2015

Researchers show how human antibodies can neutralize Marburg virus

Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola.

27 Feb 2015

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Marburg virus is Ebola's deadly cousin. The virus is up to 90 percent lethal—and doctors are desperate for tools to fight it.

27 Feb 2015

Researchers discover that cell's skeleton can trigger cell multiplication

A research team from Instituto Gulbenkian de Ciencia (IGC; Portugal), led by Florence Janody, in collaboration with Nicolas Tapon from London Research Institute (LRI; UK), discovered that the cell's skeleton can trigger the multiplication of cells through the action of proteins that control cellular rigidity.

27 Feb 2015

Carnegie Mellon study identifies intermediary neuron system that acts as synaptic cloaking device

Neuroscientists believe that the connectome, a map of each and every connection between the millions of neurons in the brain, will provide a blueprint that will allow them to link brain anatomy to brain function. But a new study from Carnegie Mellon University has found that a specific type of neuron might be thwarting their efforts at mapping the connectome by temporarily cloaking the synapses that link a wide field of neurons.

27 Feb 2015

New cancer drug enters phase I clinical trials in humans

A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma.

27 Feb 2015

Researchers report that 15% of pancreatic cancer patients may benefit from personalized therapies

Cancer researchers at Indiana University report that about 15 percent of people with pancreatic cancer may benefit from therapy targeting a newly identified gene signature.

27 Feb 2015

Researchers reveal how human immune system can fight against deadly Marburg virus

A collaborative team from The University of Texas Medical Branch at Galveston, Vanderbilt University and The Scripps Research Institute have identified mechanisms involved in antibody response to the deadly Marburg virus by studying the blood of a Marburg survivor.

27 Feb 2015

Cell News and Research

New strategy may ensure safety of adult epidermal stem cells before performing treatments

New pharmacological compounds block nerve cell damage in mouse models of MS

TxCell invited to speak at largest US meeting for investors in emerging growth companies

Feast-or-famine diet may extend lifespan, improve age-related diseases

New test can predict survival chances of women with breast cancer

New tool provides molecular details about how mutations affect cellular processes

Life-saving bone marrow transplants are not available to all who need them

Vitamin D, omega-3 fatty acids may optimize brain serotonin concentrations and function

Pediatric patients who receive quick antibiotics for fever, neutropenia have reduced PICU needs

Study finds correlation between tests for hemoglobin A1c using finger stick and oral blood

Study focuses on improving therapeutic outcomes in cancer patients through diet-drug combination

New research reveals that HIV latency is controlled by the virus itself

Study suggests benefits of calorie restriction on healthy aging

Researchers show how human antibodies can neutralize Marburg virus

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Researchers discover that cell's skeleton can trigger cell multiplication

Carnegie Mellon study identifies intermediary neuron system that acts as synaptic cloaking device

New cancer drug enters phase I clinical trials in humans

Researchers report that 15% of pancreatic cancer patients may benefit from personalized therapies

Researchers reveal how human immune system can fight against deadly Marburg virus

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