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RepliCel submits CTA for RCS-01 study to treat patients suffering from aged, UV-damaged skin

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, today announced the submission of a Clinical Trial Application (CTA) to the German Competent Authority, the Paul-Ehrlich-Institut (PEI), requesting clearance to initiate a Phase 1 clinical trial investigating the use of RCS-01 to treat patients suffering from aged and UV-damaged skin.

23 Feb 2015

Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Case Western Reserve University dental researcher Pushpa Pandiyan has discovered a new way to model how infection-fighting T cells cause inflammation in mice.

23 Feb 2015

Scientists combine principles of butterfly effect and computer simulation to predict heart disease

Scientists from Cardiff and Swansea Universities are combining the principles of the butterfly effect and computer simulation to explore new ways of predicting and controlling the beginnings of heart disease.

23 Feb 2015

MD Anderson awarded more than $22 million in research grants from CPRIT

The University of Texas MD Anderson Cancer Center has received more than $22 million in research grants this week from the Cancer Prevention and Research Institute of Texas. Approximately half of the funds awarded for Individual Investigator Research Awards went to MD Anderson faculty as well as 40 percent of total IIRA awards that include those for children's and adolescent cancer and early detection and prevention.

21 Feb 2015

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

Researchers from the Eaton-Peabody Laboratories of Massachusetts Eye and Ear and the Harvard Medical School/ Massachusetts Institute of Technology Program in Speech and Hearing Bioscience and Technology have revealed new understanding of the pathobiology behind a head and neck tumor that may someday lead to new methods of targeted drug therapy.

21 Feb 2015

Palbociclib extends progression-free survival in advanced breast cancer patients

Palbociclib, an investigational oral medication that works by blocking molecules responsible for cancer cell growth, is well tolerated and extends progression-free survival (PFS) in newly diagnosed, advanced breast cancer patients, including those whose disease has stopped responding to traditional endocrine treatments.

21 Feb 2015

Palatin introduces clinical trial website in support of bremelanotide phase 3 study for FSD treatment

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential, today announced that it has launched a clinical trial website in support of its phase 3 reconnect study with bremelanotide for the treatment of female sexual dysfunction (FSD).

20 Feb 2015

Proximity Ligation Assay helps detect effectiveness of cancer vaccines

Cancer vaccines are designed to turn the body's own immune system specifically against tumor cells. Particularly promising are vaccines that are directed against so-called neoantigens: These are proteins that have undergone a genetic mutation in tumor cells and, therefore, differ from their counterparts in healthy cells.

20 Feb 2015

Researchers develop durable antibacterial coatings of nanocomposites

Ruthless with bacteria, harmless to human cells. New, durable antibacterial coatings of nanocomposites, developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, will in future help to improve the hygiene of sportswear, and used in medicine, will reduce the rate of infections and shorten the times of in-patient hospital admissions.

20 Feb 2015

Epigenome-wide association study helps discover genes linked to allergies and asthma

Researchers from Canada, the UK, Sweden and the US have discovered more than 30 genes that strongly affect an antibody involved in allergies and asthma. Some of the genes could provide targets for drugs to treat those conditions, according to the international team's study, published online in Nature on Feb. 18.

20 Feb 2015

Virus that causes chicken pox and shingles linked to giant cell arteritis

A new study developed at the University of Colorado School of Medicine at the Anschutz Medical Campus links the virus that causes chicken pox and shingles to a condition that inflames blood vessels on the temples and scalp in the elderly, called giant cell arteritis.

20 Feb 2015

Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

Researchers from the Hospital Clinic of Barcelona (Spain) have reviewed ten years' worth of scientific studies on mitochondrial toxicity in pregnant women. Exposure to toxic agents such as viruses, certain drugs, pesticides, alcohol and tobacco cause mitochondrial diseases about which very little is known, and which are transmitted from the mother to the foetus.

20 Feb 2015

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

23andMe, Inc., the leading personal genetics company, today announced that it has been granted authority by the U.S. Food and Drug Administration (FDA) to market the first direct-to-consumer genetic test under a regulatory classification for novel devices.

20 Feb 2015

New partnership aims to create stem cell resource to study psychiatric disorders

The New York Stem Cell Foundation and the Stanley Center at the Broad Institute of MIT and Harvard are partnering to create a foundational stem cell resource to study psychiatric disorders through the production of induced pluripotent stem (iPS) cell lines from individuals with schizophrenia and other psychiatric disorders.

20 Feb 2015

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Jason Meyer, Ph.D., assistant professor of biology in the School of Science at Indiana University-Purdue University Indianapolis, has received a National Institutes of Health grant to study how glaucoma develops in stem cells created from skin cells genetically predisposed to the disease.

20 Feb 2015

Two diagnostic tests can help identify children who require surgical treatment for appendicitis

Data from two standard diagnostic tests commonly obtained in children evaluated for abdominal pain--when combined--can improve the ability of emergency department physicians and pediatric surgeons to identify those patients who should be sent to the operating room for prompt removal of an inflamed appendix; those who may be admitted for observation; and those who may safely be discharged home, according to a new study published online as an "article in press" in the Journal of the American College of Surgeons.

20 Feb 2015

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

Georgia State University has signed a license agreement with Cisen Pharmaceutical Co. Ltd., a comprehensive pharmaceutical enterprise in China, to develop cancer-fighting compounds designed by Georgia State researcher Dr. Binghe Wang, in collaboration with Professor Muxiang Zhou of Emory University, a cancer biologist.

20 Feb 2015

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs.

20 Feb 2015

Scientists identify promising new therapeutic target for prostate cancer

Keck Medicine of the University of Southern California scientists have found a promising new therapeutic target for prostate cancer. The findings offer evidence that a newly discovered member of a family of cell surface proteins called G-protein coupled receptors (GPCRs) promotes prostate cancer cell growth. The protein, GPR158, was found while the researchers were looking for new drug targets for glaucoma.

20 Feb 2015

Cell News and Research

RepliCel submits CTA for RCS-01 study to treat patients suffering from aged, UV-damaged skin

Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Scientists combine principles of butterfly effect and computer simulation to predict heart disease

MD Anderson awarded more than $22 million in research grants from CPRIT

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

Palbociclib extends progression-free survival in advanced breast cancer patients

Palatin introduces clinical trial website in support of bremelanotide phase 3 study for FSD treatment

Proximity Ligation Assay helps detect effectiveness of cancer vaccines

Researchers develop durable antibacterial coatings of nanocomposites

Epigenome-wide association study helps discover genes linked to allergies and asthma

Virus that causes chicken pox and shingles linked to giant cell arteritis

Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

New partnership aims to create stem cell resource to study psychiatric disorders

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Two diagnostic tests can help identify children who require surgical treatment for appendicitis

Georgia State signs license agreement with Cisen to develop compounds for treating cancer

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists identify promising new therapeutic target for prostate cancer

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