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Propeller tears right arm, UT Southwestern Medical Center surgeon re-attaches

"The propeller cut through the skin, muscle, tendons and bone and had removed portions of the bone," he recalled. "Basically, she had severed her arm, and it was attached only by some skin, tendon, nerve and artery."

19 Mar 2010

Genes role in protecting intestinal tract from colitis may lead to potential targets for treatment

Scientists report a protein made by a gene already associated with a handful of human inflammatory immune diseases plays a pivotal role in protecting the intestinal tract from colitis.

19 Mar 2010

Physician scientists present new findings on aspirin therapy, atrial fibrillation drug therapy and LVAD

Physician scientists from the Cedars-Sinai Heart Institute presented new findings on the effectiveness of routine aspirin therapy for preventing heart disease, a drug therapy for atrial fibrillation and the role left ventricular assist devices may play in weight reduction for obese patients with chronic end-stage heart failure who are considered for heart transplantation.

19 Mar 2010

Phase 1B clinical study initiated to evaluate safety and efficacy of PMX-60056

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat acute cardiovascular disorders and infectious diseases, has initiated a Phase 1B clinical study to evaluate the safety and efficacy of PMX-60056 in reversing the anticoagulant activity of low molecule weight heparin (LMWH).

19 Mar 2010

Genes linked to ulcerative colitis identified

A study of the human genome led by Cedars-Sinai researchers has now identified genes linked to ulcerative colitis, offering clues as to what causes the condition and potential avenues for new therapies to treat the disease.

18 Mar 2010

TRITON-TIMI 38 study evaluates response rates in patients with common genetic variant in ABCB1 gene

A new analysis of the TRITON-TIMI 38 study evaluated response rates in patients with a common genetic variant in the ABCB1 gene. Patients enrolled in the TRITON-TIMI 38 study were treated with dual antiplatelet therapy with either Plavix® (clopidogrel) plus aspirin or Effient® (prasugrel) plus aspirin and managed with percutaneous coronary intervention (PCI) following an acute coronary syndrome (ACS) event.

17 Mar 2010

Genetic test helps reduce hospitalization rates for heart patients on warfarin

Hospitalization rates for heart patients taking warfarin, the world's most-prescribed blood thinner, dropped by approximately 30 percent when genetic information was available to doctors prescribing the drug, researchers from Medco Health Solutions, Inc.-- in association with the Medco Research Institute™ -- and Mayo Clinic announced today.

17 Mar 2010

Primary results of CABG sub-analysis presented at ACC meeting

AstraZeneca (NYSE: AZN) today announced results of a new analysis of the PLATO (A Study of PLATelet Inhibition and Patient Outcomes) study which showed there were fewer deaths in patients with acute coronary syndromes (ACS) who took the investigational oral antiplatelet ticagrelor (BRILINTA™/BRILIQUE™) within seven days prior to having heart bypass surgery (coronary artery bypass graft, CABG) compared to those who took clopidogrel.

17 Mar 2010

New clinical guidelines: Early diagnosis and treatment of TAD can save lives

When actor John Ritter died suddenly in 2003 from a tear in his thoracic aorta-the large artery that carries blood from the heart to the rest of the body-that tragedy brought attention to a rare but deadly condition that takes the lives of an estimated 10,000 Americans each year.

17 Mar 2010

Iverson Genetic Diagnostics to conduct WARFARIN clinical study

Iverson Genetic Diagnostics, Inc. today announced that they will conduct a WARFARIN clinical study to assess the efficacy of gene-based testing prior to initiating warfarin anticoagulation therapy to reduce the incidence of bleeding and thromboembolic events.

16 Mar 2010

Bovie Medical reports revenues totalling $6.5M for fourth-quarter 2009

Bovie Medical Corporation, a manufacturer and marketer of electrosurgical products, today announced its financial results for the fourth quarter and year ended December 31, 2009.

16 Mar 2010

Study reveals comparable fertility rates between UFE and surgical myomectomy

Uterine fibroid embolization, a minimally invasive interventional radiology procedure that blocks blood supply to treat painful uterine fibroids, has a comparable fertility rate to myomectomy, the surgical removal of uterine fibroids, for women who want to conceive, according to the first study on the subject released at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

16 Mar 2010

Large amounts of frozen plasma are being used inappropriately

Large amounts of frozen plasma are being used inappropriately, states a commentary in CMAJ (Canadian Medical Association Journal) (pre-embargo link only).

16 Mar 2010

RE-LY study: Dabigatran etexilate shows greater reductions in stroke compared to warfarin

Data presented today at the 59th Annual Scientific Session of the American College of Cardiology have shown greater reductions in stroke in patients with atrial fibrillation (AF) for dabigatran etexilate compared to the current standard of care, warfarin, irrespective of a patient’s risk profile for stroke.

16 Mar 2010

Concurrent use of proton-pump inhibitor and clopidogrel does not elevate cardiovascular risk

Heart patients who took a stomach acid-suppressing proton-pump inhibitor along with clopidogrel - a drug that prevents blood clots - were only half as likely to be hospitalized for upper digestive tract bleeding than those who used clopidogrel alone, according to a new study supported by HHS' Agency for Healthcare Research and Quality and the National Heart, Lung, and Blood Institute at the National Institutes of Health.

16 Mar 2010

Uterine fibroids: Promising new minimally invasive treatment using high-energy ultrasound waves

There's a new interventional radiology tool showing promise in the treatment of uterine fibroids: magnetic resonance-guided focused ultrasound (MRgFUS), a minimally invasive treatment that uses high-energy ultrasound waves to generate heat at a specific point to destroy uterine fibroid tissue and relieve symptoms.

16 Mar 2010

EXPLORE-Xa study: Betrixaban reduces CRNM bleeds compared to dose-adjusted warfarin

Portola Pharmaceuticals and Merck today announced the results of EXPLORE-Xa, a Phase 2 exploratory, dose finding study of betrixaban, an investigational oral direct Factor Xa inhibitor. Results showed that a once-daily dose of oral betrixaban, given to patients with non-valvular atrial fibrillation or atrial flutter and at least one risk factor for stroke, reduced the incidence of major and clinically relevant non-major (CRNM) bleeds compared to dose-adjusted warfarin.

16 Mar 2010

Gene defects could become targets for new personalised treatments for bowel cancer

Cancer Research UK-funded scientists have discovered that the gene defects that cause some bowel cancers could become the targets for new personalised treatments. Their research is published in Cancer Cell today (Monday).

16 Mar 2010

Medafor, Magle Life Sciences of Sweden sign long-term raw material supply agreement

Medafor Inc. announced today that it has signed a long-term raw material supply agreement with Magle Life Sciences of Sweden, the supplier of the key powder component for Medafor’s patented MPH(R) (Microporous Polysaccharide Hemosphere) surgical product, which is used by surgeons to control bleeding in complex surgical operations.

15 Mar 2010

New hydrosurgery system may help manage excessive bleeding during surgery

Carnegie Mellon University's Matt Oberdier is developing a new hydrosurgery system to help physicians better manage excessive bleeding during surgery.

15 Mar 2010

Bleeding News and Research

Propeller tears right arm, UT Southwestern Medical Center surgeon re-attaches

Genes role in protecting intestinal tract from colitis may lead to potential targets for treatment

Physician scientists present new findings on aspirin therapy, atrial fibrillation drug therapy and LVAD

Phase 1B clinical study initiated to evaluate safety and efficacy of PMX-60056

Genes linked to ulcerative colitis identified

TRITON-TIMI 38 study evaluates response rates in patients with common genetic variant in ABCB1 gene

Genetic test helps reduce hospitalization rates for heart patients on warfarin

Primary results of CABG sub-analysis presented at ACC meeting

New clinical guidelines: Early diagnosis and treatment of TAD can save lives

Iverson Genetic Diagnostics to conduct WARFARIN clinical study

Bovie Medical reports revenues totalling $6.5M for fourth-quarter 2009

Study reveals comparable fertility rates between UFE and surgical myomectomy

Large amounts of frozen plasma are being used inappropriately

RE-LY study: Dabigatran etexilate shows greater reductions in stroke compared to warfarin

Concurrent use of proton-pump inhibitor and clopidogrel does not elevate cardiovascular risk

Uterine fibroids: Promising new minimally invasive treatment using high-energy ultrasound waves

EXPLORE-Xa study: Betrixaban reduces CRNM bleeds compared to dose-adjusted warfarin

Gene defects could become targets for new personalised treatments for bowel cancer

Medafor, Magle Life Sciences of Sweden sign long-term raw material supply agreement

New hydrosurgery system may help manage excessive bleeding during surgery

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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