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Statins do not interfere with Rituximab treatment for lymphomas

Statins, drugs widely prescribed to lower cholesterol, do not interfere with a commonly used medication to treat lymphomas, according to a Mayo Clinic study presented at the 50th Annual Meeting of the American Society of Hematology in San Francisco.

8 Dec 2008

Researchers study virus with unusual properties

A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell.

8 Dec 2008

Researchers discover why Gleevec-type drugs control, but do not eradicate leukemia

Oregon Health & Science University Knight Cancer Institute researchers are closer to understanding why certain chronic myeloid leukemia mutations are not stopped by the revolutionary targeted cancer pill, Gleevec, or similar therapies in that drug family.

8 Dec 2008

Older patients with acute myloid leukemia patients show promising response in drug study

Older patients with acute myloid leukemia (AML) who were once told that nothing could be done for them are finding new hope - and life - through a clinical trial at The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.

8 Dec 2008

Potential new therapy for hepatitis C treatment

Combination therapies similar to those used for HIV patients may be the best way of treating hepatitis C virus (HCV), say researchers from the University of Leeds.

8 Dec 2008

C. elegans worms may hold key to new treatments for obesity in humans

A previously unknown mutation discovered in a common roundworm holds the promise of new treatments for obesity in humans, McGill University researchers say.

8 Dec 2008

Discovery of protein that may cause breast cancer to spread

In an important finding published online in Developmental Cell , researchers at Albert Einstein College of Medicine of Yeshiva University, along with collaborators at Massachusetts Institute of Technology, have identified a protein likely responsible for causing breast cancer to spread.

8 Dec 2008

Electronic prescribing system may encourage physicians to prescribe lower-cost medications

Clinicians using an electronic prescribing system appear more likely to prescribe lower-cost medications, reducing drug spending, according to a report in the December 8/22 issue of Archives of Internal Medicine.

8 Dec 2008

Chronic myelogenous leukemia patient survey shows that side effects are a serious issue

Startling findings from a new CML (chronic myelogenous leukemia) patient survey were presented at a satellite meeting of the American Society of Hematology annual meeting, in San Francisco.

8 Dec 2008

An Achilles heel in cancer cells

A protein that shields tumor cells from cell death and exerts resistance to chemotherapy has an Achilles heel, a vulnerability that can be exploited to target and kill the very tumor cells it usually protects, researchers from the University of Illinois at Chicago show in a new study published in the Dec. 9 issue of Cancer Cell.

8 Dec 2008

Osmium as a cancer treatment

A precious metal which has never before been used in a clinical setting is being developed as an anti-cancer agent by University of Warwick researchers.

8 Dec 2008

Novel approach to disseminate trial results to study volunteers

While an estimated 2.3 million people in the U.S. take part in clinical trials every year, there currently exists no formal requirement to inform them of study results; an oversight that leaves participants confused, frustrated, and, in some cases, lacking information that may be important to their health.

8 Dec 2008

Discovery of 11 new gene sites that influence cholesterol or triglyceride levels

An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30.

8 Dec 2008

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

Genentech, Inc. and Biogen Idec have announced that two global Phase III studies in chronic lymphocytic leukemia (CLL), CLL8 and REACH, showed Rituxan (rituximab) plus chemotherapy significantly increased the time patients lived without their disease advancing, as defined by the primary endpoint of progression-free survival (PFS), when compared to chemotherapy alone.

8 Dec 2008

RHEI Pharmaceuticals starts final trial of Tibozole in China

RHEI Pharmaceuticals, Inc. has announced that the final clinical trial for Tibozole, a locally active antifungal with low dose miconazole in a patented mucoadhesive system, has been initiated in China.

8 Dec 2008

Scientists find 12 new genes with potential as drug targets

Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

8 Dec 2008

Study finds it generally safe to withdraw anti-seizure medication in children with epilepsy

A new Mayo Clinic study found that it is generally safe to withdraw anti-seizure medications in children with epilepsy who have achieved seizure-freedom while on the medication.

8 Dec 2008

FDA advisory committee recommends approval of LATISSE as a treatment for hypotrichosis of eyelashes

Allergan, Inc. has announced the U.S. Food and Drug Administration (FDA) Dermatologic and Ophthalmic Drugs Advisory Committee (DODAC) voted unanimously (9-0) to recommend that the FDA approve LATISSE (bimatoprost solution 0.03%) as a treatment for hypotrichosis (or reduced amount of hair) of the eyelashes.

8 Dec 2008

FDA advisory committee to dscuss PMA for Genzyme's Synvisc-One

Genzyme Corporation has announced that its Premarket Approval (PMA) application supplement for Synvisc-One (hylan G-F 20) will be discussed this Tuesday, December 9th, at a public meeting of the FDA's Orthopaedic and Rehabilitation Devices Advisory Committee in Gaithersburg, Maryland.

8 Dec 2008

FDA advisory committee recommends approval for Bausch & Lomb's besifloxacin ophthalmic suspension

The U.S. Food and Drug Administration (FDA) Dermatologic and Ophthalmic Drugs Advisory Committee today voted unanimously to recommend approval of Bausch & Lomb's besifloxacin ophthalmic suspension, 0.6%, for the treatment of bacterial conjunctivitis.

8 Dec 2008

Drugs News and Research

Statins do not interfere with Rituximab treatment for lymphomas

Researchers study virus with unusual properties

Researchers discover why Gleevec-type drugs control, but do not eradicate leukemia

Older patients with acute myloid leukemia patients show promising response in drug study

Potential new therapy for hepatitis C treatment

C. elegans worms may hold key to new treatments for obesity in humans

Discovery of protein that may cause breast cancer to spread

Electronic prescribing system may encourage physicians to prescribe lower-cost medications

Chronic myelogenous leukemia patient survey shows that side effects are a serious issue

An Achilles heel in cancer cells

Osmium as a cancer treatment

Novel approach to disseminate trial results to study volunteers

Discovery of 11 new gene sites that influence cholesterol or triglyceride levels

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

RHEI Pharmaceuticals starts final trial of Tibozole in China

Scientists find 12 new genes with potential as drug targets

Study finds it generally safe to withdraw anti-seizure medication in children with epilepsy

FDA advisory committee recommends approval of LATISSE as a treatment for hypotrichosis of eyelashes

FDA advisory committee to dscuss PMA for Genzyme's Synvisc-One

FDA advisory committee recommends approval for Bausch & Lomb's besifloxacin ophthalmic suspension

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