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Novel micro-catheter fluorescent dye method to treat aneurysm in deep brain

In March 2013, Eric Wagner told his wife to call 9-1-1 because he was feeling the worst that he had ever felt. He was rushed by EMS to University Hospitals (UH) Ahuja Medical Center, and then airlifted to UH Case Medical Center, where brain scans showed that he had a ruptured aneurysm, a leaking blister on a blood vessel that was letting blood flow into his brain and causing a stroke.

27 Nov 2013

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These "daughter" cells must be produced at a rate of about one million per second to constantly replenish the body's blood supply.

27 Nov 2013

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

People inherit different versions of any particular gene, and some genes affect how patients process and metabolize medicines. This especially holds true for people with cardiovascular (CV) disease. They may be fast, slow or non-metabolizers and might also react badly (with serious adverse events) to certain drug therapies or not at all.

27 Nov 2013

Fluxion Biosciences reports first study results from early stage NSCLC patients

Fluxion Biosciences, Inc. announced the presentation of the first pilot study results aimed at isolating circulating tumor cells (CTCs) from early stage non-small cell lung cancer (NSCLC) patients obtained in collaboration with Dr. Max Diehn's lab at Stanford University. CTCs are cells that disseminate from primary tumors and contribute to the spread of the disease to other parts of the body.

From Fluxion Biosciences 27 Nov 2013

Study reveals how brain and olfactory system operate to process scent, odor signals

Our sense of smell is often the first response to environmental stimuli. Odors trigger neurons in the brain that alert us to take action.

27 Nov 2013

EPCs: A promising therapy for type 1 diabetes

Pancreatic islet transplantation is a promising therapy for treating type 1 diabetes, but the majority of transplanted cells die soon after they are transplanted.

27 Nov 2013

Researchers develop prototype spacesuit biosensors to monitor astronauts' health

Kansas State University researchers are improving astronauts' outerwear for outer space. The collaborative team -- which includes electrical and computer engineering professors and more than a dozen students -- envisions a future spacesuit that could monitor astronauts' health and use body heat to power electronics.

27 Nov 2013

Bioxodes completes seed funding round to bring Ir-CPI product into pre-clinical development

Bioxodes SA, a company developing products derived from natural sources, has completed a EUR 2.6 million (USD 3.5 million) first seed funding round with a consortium of business angels and Belgian investment funds. EUR 1.6 million is from the European Regional Development Fund and the Walloon Region in Belgium via the Retech program for Research and Technology. It will be used to bring the company’s lead product Ir-CPI into pre-clinical development over the next 18 months.

27 Nov 2013

Merck announces approval of NOXAFIL delayed-release tablets by FDA

Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved NOXAFIL® (posaconazole) 100 mg delayed-release tablets.

27 Nov 2013

African Americans have double the risk of end-stage renal disease compared to white Americans

In the United States, African Americans have approximately twice the risk of end-stage renal disease compared to white Americans, despite a similar prevalence in earlier stages of chronic kidney disease. A large study co-authored by George Washington University researcher Dominic Raj, M.D., identifies factors that mediate differences in the progression of chronic kidney disease between black patients and white patients, as well as among black patients, in order to reduce the excess burden of end-stage renal disease and its complications in black patients.

27 Nov 2013

Survivors of hematopoietic stem cell transplant benefit from expressive helping

A new study finds that survivors of hematopoietic stem cell transplant, an aggressive treatment for blood cancers, benefited from a two-part peer support process the authors call expressive helping.

27 Nov 2013

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), a devastating cancer that is incurable in 70% of patients.

27 Nov 2013

Study shows dl-3n-butylphthalide may have protective effects against diffuse brain injury

Dl-3n-butylphthalide can effectively treat cerebral ischemia; however, the mechanisms underlying the effects of dl-3n-butylphthalide on microcirculation disorders following diffuse brain injury remain unclear.

27 Nov 2013

International researchers report significant findings on vascular abnormality outside the brain

Studies on Alzheimer's disease and other forms of dementia have long focused on what's happening inside the brain. Now an international research team studying Alzheimer's and mild cognitive impairment is reporting potentially significant findings on a vascular abnormality outside the brain.

27 Nov 2013

San Diego School of Medicine receives grant to provide professional training to senior drivers

For the seventh consecutive year, the Training, Research and Education for Driving Safety (TREDS) program at the University of California, San Diego School of Medicine has been awarded a grant from the California Office of Traffic Safety (OTS) that will help keep our roadways and senior drivers safe through professional training.

27 Nov 2013

Research: Human neural stem cells could improve blood flow in critical limb ischemia

New research has shown human neural stem cells could improve blood flow in critical limb ischemia through the growth of new vessels. Critical limb ischemia is a disease that severely obstructs arteries and reduces the blood flow to legs and feet. CLI remains an unmet clinical problem and with an ageing population and the rise in type II diabetes, the incidence of CLI is expected to increase.

27 Nov 2013

HIV patients face higher risk of virologic failure than previously thought

People with human immunodeficiency virus (HIV) run a higher risk of virologic failure than previously thought, even when their number of RNA copies of the retrovirus per millilitre of blood is slightly above the detection threshold, according to a study by Claudie Laprise at the University of Montreal's Department of Social and Preventative Medicine.

26 Nov 2013

Researchers successfully target T lymphocytes which play key role in body's immune response

Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes - which play a central role in the body's immune response - with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA (miRNA).

26 Nov 2013

Alternative treatment for autism focuses on controlling the 'fight or flight' response

A novel approach to treating children diagnosed with autism spectrum disorder could help them navigate their world by teaching them to turn their symptoms into strengths.

26 Nov 2013

Asparagine found in meat, eggs and dairy products is important for normal brain development

Asparagine, found in foods such as meat, eggs, and dairy products, was until now considered non-essential because it is produced naturally by the body. Researchers at the University of Montreal and its affiliated CHU Sainte-Justine Hospital found that the amino acid is essential for normal brain development.

26 Nov 2013

Blood News and Research

Novel micro-catheter fluorescent dye method to treat aneurysm in deep brain

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

Fluxion Biosciences reports first study results from early stage NSCLC patients

Study reveals how brain and olfactory system operate to process scent, odor signals

EPCs: A promising therapy for type 1 diabetes

Researchers develop prototype spacesuit biosensors to monitor astronauts' health

Bioxodes completes seed funding round to bring Ir-CPI product into pre-clinical development

Merck announces approval of NOXAFIL delayed-release tablets by FDA

African Americans have double the risk of end-stage renal disease compared to white Americans

Survivors of hematopoietic stem cell transplant benefit from expressive helping

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

Study shows dl-3n-butylphthalide may have protective effects against diffuse brain injury

International researchers report significant findings on vascular abnormality outside the brain

San Diego School of Medicine receives grant to provide professional training to senior drivers

Research: Human neural stem cells could improve blood flow in critical limb ischemia

HIV patients face higher risk of virologic failure than previously thought

Researchers successfully target T lymphocytes which play key role in body's immune response

Alternative treatment for autism focuses on controlling the 'fight or flight' response

Asparagine found in meat, eggs and dairy products is important for normal brain development

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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