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Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Aravive Biologics, Inc. announced today that the company has demonstrated clinical proof-of-mechanism for AVB-S6-500 in neutralizing GAS6, based on analysis of the single ascending dose portion of the ongoing Phase 1 study.

10 May 2018

Newly developed technique allows researchers to study liver stage malaria

A newly developed technique allows researchers to more easily study malaria outside the human body during the earliest point of infection, the liver.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Using human induced pluripotent stem cells for therapeutic drug testing

Researchers at Li Ka Shing Faculty of Medicine of The University of Hong Kong have successfully demonstrated the use of human induced pluripotent stem cells from patients' skin cells for therapeutic drug testing.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

New study evaluates expression of PD-L1 in human medulloblastoma

This study evaluated the expression of PD-L1 and markers of immune mediated resistance in human medulloblastoma, the most common malignant pediatric brain tumor.

3 May 2018

Stem cells cultured in vitro self-assemble into embryo

An embryo has been created in vitro from mouse stem cells cultured with a 3D scaffold. The resulting structure was remarkably similar to a natural mouse embryo.

3 May 2018

EKF receives FDA clearance and CLIA waiver for reagent-free hemoglobin analyzer

EKF Diagnostics, the global in vitro diagnostics company, announces U.

From EKF Diagnostics 2 May 2018

Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Researchers at University of California San Diego School of Medicine are preparing a first-of-its-kind, multidisciplinary investigation to determine if and how cannabidiol, a non-psychoactive compound found in the cannabis plant, provides therapeutic benefit to children with severe symptoms of autism spectrum disorder.

27 Apr 2018

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

The work of researchers Francesc Viñals and Mariona Graupera at the Bellvitge Biomedical Research Institute - Catalan Institute of Oncology - University of Barcelona, together with Dr. Antoni Riera-Mestre, has led to a new potential treatment for Hereditary Hemorrhagic Telangiectasia or Rendu-Osler Syndrome, a rare disease that affects blood vessels and had no described treatment.

26 Apr 2018

Radiofrequency ablation: A new, emerging procedure burns cancer cells

Some 80,000 Americans will be diagnosed with a brain tumor this year according to the American Brain Tumor Association.

25 Apr 2018

Preantral zinc deficiency may affect fertility months

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility.

24 Apr 2018

Scientists identify new DNA structure within living human cells

For the first time, a team of researchers have identified a new DNA structure inside cells that has an entirely different shape to the iconic “double helix” shape uncovered by Watson and Crick in 1953.

24 Apr 2018

Can GAC Be Used to Control Priority Unregulated DBPs in Drinking Water?

In this interview, Prof. Susan Richardson discusses the use of GAC to control disinfection by-products.

From Pittcon 23 Apr 2018

Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance

Researchers identified novel chromosomal mutations and described their role in the development of resistance of Escherichia coli (E. coli) to broad-spectrum antibiotic fosfomycin, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

in vitro News and Research

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Newly developed technique allows researchers to study liver stage malaria

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Using human induced pluripotent stem cells for therapeutic drug testing

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

New study evaluates expression of PD-L1 in human medulloblastoma

Stem cells cultured in vitro self-assemble into embryo

EKF receives FDA clearance and CLIA waiver for reagent-free hemoglobin analyzer

Scientists discover potential therapeutic target for devastating premature aging disease

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Study to examine whether cannabidiol provides therapeutic benefit to children with autism

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

Radiofrequency ablation: A new, emerging procedure burns cancer cells

Preantral zinc deficiency may affect fertility months

Scientists identify new DNA structure within living human cells

Can GAC Be Used to Control Priority Unregulated DBPs in Drinking Water?

Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

New CRISPR tool allows DNA editing outside of the cell

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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