B Cell News and Research

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Synthetic biology technology could lead to new antibiotics, modified protein-generators

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube.

30 Jun 2013

Molecular protein folding process may help medical researchers understand and treat diseases

Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.

30 Jun 2013

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

A new clinical research study at Roswell Park Cancer Institute (RPCI) will assess the safety and efficacy of a novel immunotherapy approach to treating advanced melanoma. Developed at RPCI by Roswell Park researchers, the investigational vaccine shows promise for treating tumors in patients with stage III/stage IV melanoma, and perhaps as a future therapy for other solid-tumor cancers as well.

30 Jun 2013

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M), has found that patients receiving the transplants, when compared to a control group of TD2M patients who did not receive transplantation, required less insulin post-transplantation.

30 Jun 2013

New procedure to treat acid reflux can prevent chronic rejection in lung transplant patients

A Loyola University Medical Center study suggests that a procedure to treat acid reflux could help prevent chronic rejection in lung transplant patients.

30 Jun 2013

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Science knows that arsenic and estrogen can cause cancer. At certain very low levels, the chemicals offer little to no threats to human health.

29 Jun 2013

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

A team of researchers from Rush University, Yale University, the University of Colorado and the St. Kitts Biomedical Research Foundation transplanted human embryonic stem cells into primate laboratory animals modeled with Parkinson's disease and found "robust survival" of the cells after six weeks and indications that the cells were "well integrated" into the host animals.

29 Jun 2013

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

A team of researchers in Poland who treated three of six paraplegics with spinal cord injury using transplanted olfactory ensheathing cells found that the three treated patients showed neurological improvement and no adverse effects while the three control patients who did not receive transplants saw no improvement.

29 Jun 2013

$Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women$

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

Higher levels of omega-3 fatty acids in the blood may reduce the risk for hip fractures in postmenopausal women, recent research suggests.

28 Jun 2013

New approaches to regenerate insulin-producing cells for type I diabetes

They have also shown that any pancreatic β cells can be regenerated several times and that chemically-induced diabetes in mice can thus be "treated" repeatedly. The challenge for the researchers is now to show that these procedures can be applied to humans.

28 Jun 2013

Scientists use brain-tracing technique to untangle circuitry that guides brain function

The power of the brain lies in its trillions of intercellular connections, called synapses that together form complex neural "networks." While neuroscientists have long sought to map these individual connections to see how they influence specific brain functions, traditional techniques have been unsuccessful.

28 Jun 2013

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

Understanding how the protein km23-1 enables in the spread of colon cancer may lead to new treatments for the disease, according to researchers at Penn State College of Medicine.

28 Jun 2013

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

RUCDR Infinite Biologics, the world's largest university-based biorepository, received a $44.5 million Cooperative Agreement award from the National Institute of Mental Health earlier this month to support its NIMH Center for Collaborative Genomics Research on Mental Disorders, which provides services to NIMH-funded scientists engaged in genomic research on mental disorders.

28 Jun 2013

Decorin protein in blood inhibits tumor progression, say researchers

Researchers from Thomas Jefferson University's Kimmel Cancer Center have discovered that decorin, a naturally occurring protein that circulates in the blood, acts as a potent inhibitor of tumor growth modulating the tumor microenvironment.

28 Jun 2013

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Malaria is one of the most important infectious diseases in the developing world, with the absence of a vaccine and the development of parasite resistance to commonly used antimalarial drugs complicating efforts to fight the deadly disease.

28 Jun 2013

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Scientist at Charité - Universitätsmedizin Berlin have used a computer simulation for predicting the effectiveness of various combination therapies for colon tumors. The study has been published in the current issue of the professional journal Molecular Systems Biology*.

28 Jun 2013

Study: Children with Crohn's disease have enterovirus in their intestines

A new study reveals that all children with Crohn's disease that were examined had a commonly occurring virus - an enterovirus - in their intestines. This link has previously not been shown for this chronic inflammatory intestinal disorder. The findings are being published today in the latest issue of the international journal Clinical and Translational Gastroenterology.

28 Jun 2013

TSRI scientists identify small molecules to control genetic defect responsible for muscular dystrophy

For the first time, scientists from the Florida campus of The Scripps Research Institute have identified small molecules that allow for complete control over a genetic defect responsible for the most common adult onset form of muscular dystrophy.

28 Jun 2013

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Type 1 diabetes is an attack by the immune system of the islet of Langerhans within the pancreas. Basically, the islet of Langerhans harbor beta cells, which produce insulin and when the islets are attacked, the beta cells destruct and there is no more insulin. When the insulin level goes low, blood glucose levels go high and that creates a problem.

28 Jun 2013

Study examines role of six-layered cerebral cortex in processing sensory information

A series of studies conducted by Randy Bruno, PhD, and Christine Constantinople, PhD, of Columbia University's Department of Neuroscience, topples convention by showing that sensory information travels to two places at once: not only to the brain's mid-layer (where most axons lead), but also directly to its deeper layers. The study appears in the June 28, 2013, edition of the journal Science.

28 Jun 2013

B Cell News and Research

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Molecular protein folding process may help medical researchers understand and treat diseases

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

New procedure to treat acid reflux can prevent chronic rejection in lung transplant patients

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

Higher levels of Omega-3 fatty acids may reduce risk for hip fractures in postmenopausal women

New approaches to regenerate insulin-producing cells for type I diabetes

Scientists use brain-tracing technique to untangle circuitry that guides brain function

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

Decorin protein in blood inhibits tumor progression, say researchers

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Study: Children with Crohn's disease have enterovirus in their intestines

TSRI scientists identify small molecules to control genetic defect responsible for muscular dystrophy

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Study examines role of six-layered cerebral cortex in processing sensory information

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