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New diabetes has little impact on outcomes in elderly hypertensives

Established, but not newly diagnosed, diabetes is associated with reduced survival among elderly patients with hypertension, shows an analysis of the ANBP2 study.

25 Nov 2013

PCBs banned by the US 3 decades ago hurt seniors' cognitive performance

Although PCBs have been banned in the United States since 1979, University of Montreal and CHU Sainte-Justine researcher Maryse Bouchard has found that higher levels of the toxin was associated with lower cognitive performance in seniors.

25 Nov 2013

Researchers identify potential therapeutic target in treatment of certain AML

Acute myeloid leukemia (AML) is a group of heterogeneous diseases with considerable diversity in terms of genetic abnormalities. Mutations of CEBPA, a tumour suppressor, are found in about 10 per cent of human AML patients. In two separate studies on CEBPA mutations in AML subtypes, researchers successfully identified and validated a gene known as Sox4 as a potential therapeutic target and a class of anti-cancer drugs, histone deacetylase (HDAC) inhibitors, as potential candidates in the treatment of certain AML.

25 Nov 2013

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Medicines Agency's: Committee for Medicinal Products for Human Use has adopted a positive opinion for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.

25 Nov 2013

Research: Notch protein plays essential role in triggering T-cell development

The lab of Avinash Bhandoola, PhD, professor of Pathology and Laboratory Medicine, has studied the origins of T cells for many years. One protein called Notch, which has well-known roles in the development of multiple tissues, plays an essential role in triggering T-cell development.

25 Nov 2013

Researchers identify immune cell protein that sets off body's initial response against viral infection

A Massachusetts General Hospital-led research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. The report that will be published in an upcoming issue of Nature Immunology and is receiving early online release describes finding that a protein called GEF-H1 is essential to the ability of macrophages - major contributors to the innate immune system - to respond to viral infections like influenza.

25 Nov 2013

Tuna sashimi consumption can increase rates of cardiovascular disease

The study showed that tuna sashimi contains the highest levels of methylmercury in fish-sushi, based on samples taken from across the USA.

25 Nov 2013

Researchers discover how type 2 diabetes drug metformin actually works

Researchers from St. Vincent's Institute of Medical Research in Melbourne, Australia, in collaboration with researchers at McMaster University in Canada, are reportedly the first to discover how the type 2 diabetes drug metformin actually works, providing a molecular understanding that could lead to the development of more effective therapies. Mass spectrometry technologies from AB SCIEX, a global leader in analytical technologies, played a critical role in the analysis that led to this breakthrough finding.

25 Nov 2013

Research roundup: Meeting the needs of assisted living residents; Medicaid expansion and community health centers; money follows the person

Assisted living facilities provide housing and care to persons unable to live independently, and who often have increasing medical needs. Disease outbreaks illustrate challenges of maintaining adequate resident protections in these facilities. ... Of the 50 states, 84% specify health-based admissions criteria to assisted living facilities; 60% require licensed health care professionals to oversee medical care; ... There is wide variation in how assisted living facilities are regulated in the United States.

25 Nov 2013

Transarterial embolization procedure helps reduce body weight

A new study reports that individuals who underwent embolization of the left gastric artery for gastrointestinal bleeding experienced a 7.9 percent decrease in body weight three months after the procedure. Results of the study, which offer a potential new avenue for obesity research, will be presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2013

Scientists find link between airborne allergies and risk of blood cancers in women

A team of scientists looking into the interplay of the immune system and cancer have found a link between a history of airborne allergies - in particular to plants, grass and trees - with risk of blood cancers in women.

25 Nov 2013

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

The physical decline experienced by Parkinson's disease patients eventually leads to disability and a lower quality of life. Depending on the individual, the disorder can progress rapidly or slowly.

25 Nov 2013

CVD expert requests Mexican government to carry out mandatory screening for 18-year-olds

A cardiovascular disease expert is calling for mandatory screening of 18 year-old Mexicans to halt the CVD epidemic plaguing the nation. Cardiovascular risk factors will be a key theme at the Mexican Congress of Cardiology, held 23 to 27 November in Leon, Guanajuato, Mexico. The Congress is organised by the Mexican Society of Cardiology and features a collaborative programme with the European Society of Cardiology.

23 Nov 2013

Sorin Group receives CE Mark approval for Solo Smart stentless aortic valve

Sorin Group, a global medical company and a leader in the treatment of cardiovascular diseases, announced today that it has received CE Mark approval for the Solo Smart stentless aortic valve.

23 Nov 2013

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

Janssen-Cilag International NV announced today that the European Commission has approved INVOKANA (canagliflozin) in the European Union for the treatment of adults with type 2 diabetes mellitus, to improve glycaemic control[1]. Canagliflozin is an oral, once-daily medication, which belongs to a new class of medications called sodium glucose co-transporter 2 (SGLT2) inhibitors.

23 Nov 2013

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Janssen Therapeutics, Division of Janssen Products, LP, announced today the U.S. Food and Drug Administration has approved OLYSIO (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.

23 Nov 2013

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Bayer HealthCare and Onyx Pharmaceuticals, Inc., an Amgen subsidiary, today announced that the U.S. Food and Drug Administration has approved a supplemental New Drug Application for the oral multi-kinase inhibitor NEXAVAR (sorafenib) tablets for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.

23 Nov 2013

Nanotechnology-based technique: A painless method for maintaining healthy blood sugar levels

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections - rather than using needles to give themselves multiple insulin injections each day.

22 Nov 2013

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has received approval for the treatment of Macular Edema Following Central Retinal Vein Occlusion from the Japanese Ministry of Health, Labour and Welfare.

22 Nov 2013

First molecular test developed to detect eosinophilic esophagitis

Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis, a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago.

22 Nov 2013

Blood News and Research

New diabetes has little impact on outcomes in elderly hypertensives

PCBs banned by the US 3 decades ago hurt seniors' cognitive performance

Researchers identify potential therapeutic target in treatment of certain AML

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Research: Notch protein plays essential role in triggering T-cell development

Researchers identify immune cell protein that sets off body's initial response against viral infection

Tuna sashimi consumption can increase rates of cardiovascular disease

Researchers discover how type 2 diabetes drug metformin actually works

Research roundup: Meeting the needs of assisted living residents; Medicaid expansion and community health centers; money follows the person

Transarterial embolization procedure helps reduce body weight

Scientists find link between airborne allergies and risk of blood cancers in women

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

CVD expert requests Mexican government to carry out mandatory screening for 18-year-olds

Sorin Group receives CE Mark approval for Solo Smart stentless aortic valve

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Nanotechnology-based technique: A painless method for maintaining healthy blood sugar levels

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

First molecular test developed to detect eosinophilic esophagitis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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