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Scientists identify key mechanism of drug resistance in breast cancer patients

CANCER RESEARCH UK funded scientists have discovered why some breast cancers are resistant to the commonly used drug tamoxifen, their findings are published in Cancer Research.

24 Feb 2010

FDA: Invirase-Norvir combination therapy for HIV may adversely affect the heart

The U.S. Food and Drug Administration today announced preliminary data suggesting that Invirase (saquinavir) in combination with Norvir (ritonavir) may have potentially important adverse effects on the heart.

24 Feb 2010

Alliance Biosciences to provide engineering and biosafety guidance for Nyumbani's HIV/TB diagnostic facility

Alliance Biosciences reached an agreement with the Nyumbani Children's Home in Kenya to provide engineering and biosafety guidance to Nyumbani's planned HIV/TB diagnostic facility.

24 Feb 2010

ViiV Healthcare highlights S/GSK1349572, SELZENTRY and EPZICOM for HIV/AIDS at 17th CROI

At the 17th Conference on Retroviruses and Opportunistic Infections (CROI), ViiV Healthcare presented new data across its broad range of investigational and current medicines for the treatment of HIV/AIDS. Highlighted data at the conference included an oral presentation on the investigational integrase inhibitor, S/GSK1349572, as well as data presentations on SELZENTRY® (maraviroc) and EPZICOM® (abacavir/lamivudine).

24 Feb 2010

Prednisolone associated with recurrence of CAP after its withdrawal

Patients hospitalized with mild to moderate community-acquired pneumonia (CAP) should not be routinely prescribed prednisolone, a corticosteroid, as it is associated with a recurrence of symptoms after its withdrawal, according to the first randomized double-blind clinical trial to address the subject.

24 Feb 2010

Study indicates Finasteride therapy may benefit women suffering from hair loss

Molecular dermatology research and development innovator HairDX today announced the results of a six month pilot study that presents, for the first time, evidence that genetic mechanisms may predict treatment response to Finasteride for postmenopausal female Androgenetic Alopecia (female hair loss).

24 Feb 2010

New Barts Cancer Research UK Centre launched

A new cancer centre, launched today, puts London at the forefront of cancer research.

23 Feb 2010

Medtronic third-quarter revenues up by 10%

Medtronic, Inc. today reported financial results for the third quarter of fiscal year 2010, which ended January 29, 2010.

23 Feb 2010

Lexicon Pharmaceuticals reports positive results from Phase 2 clinical trials for IBS and type 2 diabetes

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, today updated its drug development progress and reported financial results for the three months and year ended December 31, 2009.

23 Feb 2010

NCC, Pfizer provide over 10M units of ReFacto Antihemophilic Factor to underserved hemophilia patients

The National Cancer Coalition (NCC) is pleased to announce its recent collaboration with Pfizer, Inc to provide hemophilia medicines to underserved patients in the developing world. To date, NCC has received more than 10 million international units of ReFacto® Antihemophilic Factor (Recombinant), a therapy used for the treatment and prevention of bleeding in people with hemophilia A, to assist patients who otherwise would have little opportunity for adequate treatment. The value of this donation is more than $13 million, and it will help many hundreds of hemophilia patients around the world.

23 Feb 2010

Catheter insertion technology patent acquired by Acacia Research subsidiary

Acacia Research Corporation announced today that a subsidiary has acquired patents for catheter insertion technology.

23 Feb 2010

Key mechanism that makes brain cells become tumorous identified

Researchers from the Peninsula Medical School in Plymouth (UK), the Memorial Sloan-Kettering Cancer Center in New York, Cornell University in New York, Weil Medical College in New York and the Center for Neural Tumour Research in Los Angeles, have for the first time identified a key mechanism that makes certain cells become tumorous in the brain. The resulting tumours occur most often spontaneously but can also occur in numbers as part of the inherited disease Neurofibromatosis type 2.

23 Feb 2010

OUTCOME, REACH Call partner to integrate stroke-telemedicine data into Get With The Guidelines–Stroke program

Outcome Sciences, Inc., the leading provider of patient registries, studies, and technologies for evaluating real-world outcomes, and REACH Call, the leading provider of web-based telemedicine services, today announced a partnership to integrate stroke-telemedicine data into the American Heart Association’s Get With The Guidelines®–Stroke program.

23 Feb 2010

TCAD therapy active and synergistic against drug resistant influenza virus strains

Adamas Pharmaceuticals, Inc., a privately held company, reported today on the publication of results from a preclinical study that demonstrated the synergistic effects of triple combination antiviral drug (TCAD) therapy against multiple strains of seasonal, pandemic, and avian influenza A (H1N1, H3N2 and H5N1) virus, including three strains of amantadine resistant pandemic H1N1 and two strains of oseltamivir resistant seasonal H1N1.

23 Feb 2010

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Cayston® (aztreonam for inhalation solution) as a treatment to improve respiratory symptoms in cystic fibrosis patients with Pseudomonas aeruginosa. Cayston’s safety and efficacy have not been established in pediatric patients below the age of 7, patients with forced expiratory volume in one second of less than 25 percent or greater than 75 percent predicted, or patients colonized with Burkholderia cepacia.

23 Feb 2010

Obecure granted patent covering betahistine with olanzapine for mitigating antipsychotic drug associated weight gain

Obecure Ltd., a subsidiary of Bio-Light Israeli Life Science Investments Ltd., has received notice of allowance from the US Patent Office for its two key patent applications covering methods of use and compositions covering the use of betahistine with olanzapine for the mitigation of the serious weight gain associated as a side effect of the antipsychotic drug.

23 Feb 2010

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

The severe shortage of specially-trained intensivist physicians has hospital intensive care units (ICUs) nationwide struggling to staff units with critical care teams led by intensivists, even though the presence of these specially trained physicians reduces the risk of death for patients in the ICU.

23 Feb 2010

Humans can harbor bacteria in gallstones, infect others with active typhoid fever

A new study suggests that the bacteria that cause typhoid fever collect in tiny but persistent communities on gallstones, making the infection particularly hard to fight in so-called "carriers" - people who have the disease but show no symptoms.

23 Feb 2010

Centric Health Resources and CHT to create sustainable healthcare system for Americans

St. Louis-based Centric Health Resources, Inc. joined the Center for Health Transformation (CHT) a high-impact collaboration of private and public sector leaders committed to creating a 21st Century Intelligent Health System that saves lives and money for all Americans.

23 Feb 2010

Head and neck tumors in close proximity to sensitive areas may lead to brain injury, visionary risk or hearing loss

When head and neck tumors - from sinus tumors to acoustic neuromas attached to the hearing and balance nerve at the base of the skull - are located in close proximity to such sensitive areas such as the brain and eyes, they are particularly dangerous due to possible brain injury, visionary risk or hearing loss.

23 Feb 2010

Therapy News and Research

Scientists identify key mechanism of drug resistance in breast cancer patients

FDA: Invirase-Norvir combination therapy for HIV may adversely affect the heart

Alliance Biosciences to provide engineering and biosafety guidance for Nyumbani's HIV/TB diagnostic facility

ViiV Healthcare highlights S/GSK1349572, SELZENTRY and EPZICOM for HIV/AIDS at 17th CROI

Prednisolone associated with recurrence of CAP after its withdrawal

Study indicates Finasteride therapy may benefit women suffering from hair loss

New Barts Cancer Research UK Centre launched

Medtronic third-quarter revenues up by 10%

Lexicon Pharmaceuticals reports positive results from Phase 2 clinical trials for IBS and type 2 diabetes

NCC, Pfizer provide over 10M units of ReFacto Antihemophilic Factor to underserved hemophilia patients

Catheter insertion technology patent acquired by Acacia Research subsidiary

Key mechanism that makes brain cells become tumorous identified

OUTCOME, REACH Call partner to integrate stroke-telemedicine data into Get With The Guidelines–Stroke program

TCAD therapy active and synergistic against drug resistant influenza virus strains

FDA issues approval for Gileads's Cayston for respiratory symptoms in cystic fibrosis

Obecure granted patent covering betahistine with olanzapine for mitigating antipsychotic drug associated weight gain

Multidisciplinary, team-based approach can reduce mortality rates in ICUs

Humans can harbor bacteria in gallstones, infect others with active typhoid fever

Centric Health Resources and CHT to create sustainable healthcare system for Americans

Head and neck tumors in close proximity to sensitive areas may lead to brain injury, visionary risk or hearing loss

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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