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UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

UT Southwestern Medical Center researchers seeking novel ways to combat cancer found that giving acetate, a major compound produced in the gut by host bacteria, to mice sped up the growth and metastasis of tumors.

18 Feb 2015

New compound appears to play role in development of opioid tolerance

While opioids are a widely used treatment for pain, patients who take them on a regular basis can become tolerant, requiring a higher dose for continued pain relief. In a study published in Anesthesiology, the official medical journal of the American Society of Anesthesiologists, researchers identified a compound that appears to play a role in the development of opioid tolerance.

18 Feb 2015

Bacteria's DNA can pass trait to offspring in a way similar to parents' own DNA

It's a firmly established fact straight from Biology 101: Traits such as eye color and height are passed from one generation to the next through the parents' DNA.

17 Feb 2015

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Researchers at Yale School of Medicine have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer's disease.

17 Feb 2015

Experts discuss therapeutic potential of medical cannabis in a symposium organized by MUHC

While debate about recreational marijuana use continues, researchers are investigating the effectiveness of cannabis for treating pain, spasticity, and a host of other medical problems. In a symposium organized by the McGill University Health Centre as part of the 2015 American Association for the Advancement of Science Annual Meeting held this week in San Jose, California, world-renowned experts from North America and the U.K. share their perspectives on the therapeutic potential of medical cannabis and explore the emerging science behind it.

16 Feb 2015

Researchers develop new method for preventing destructive activity of osteoclasts

Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of these very same osteoclast cells. Researchers from the CNRS, Inserm and the Université de Montpellier and Université Jean Monnet - Saint-étienne have developed a new approach for preventing the destructive activity of osteoclasts without affecting their viability.

12 Feb 2015

SRI Biosciences awarded contract to develop novel polymers to neutralize chemical, biological threats

SRI Biosciences, a division of SRI International, has been awarded a $10 million contract under a DARPA program to reimagine how proteins are constructed and to develop novel medicines and diagnostics as countermeasures to chemical and biological threats.

12 Feb 2015

New method of spectral analysis identifies fingerprints of chemical substances with greater accuracy

Elements and their compounds will no longer be able to hide in mixtures, even if the latter are made up of many components.

11 Feb 2015

Researchers close to novel therapy to treat levodopa-induced dyskinesia

Involuntary dyskinetic movements induced by treatment with levodopa (L-dopa) are a common problem for people with Parkinson's disease. Now, however, researchers at Karolinska Institutet and Lund University in Sweden seem to be close to a novel therapy to this distressing side effect.

11 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Study: Simple blood test could predict risk of developing dementia

Scientists at Rigshopitalet, Herlev Hospital and the University of Copenhagen identify a new biomarker that can predict the risk of developing dementia by way of a simple blood test. In the long term, this could mean better prevention and thus at least postponement of the illness and at best evading the development all together.

10 Feb 2015

New findings could pave way to develop drug therapies for necrosis-related diseases

Strokes, heart attacks and traumatic brain injuries are separate diseases with certain shared pathologies that achieve a common end - cell death and human injury due to hypoxia, or lack of oxygen.

9 Feb 2015

New compound may lead to development of potential therapeutics for neuropathic pain

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that which is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

7 Feb 2015

41% of the British population unaware of the role of diet in cancer development

Surprising new statistics reveal that 41% of the British population are oblivious to the role that diet plays in the development of cancer - and even those with a family history of the disease are failing to consume potentially "cancer-preventing" compounds in their daily diet.

6 Feb 2015

MIT engineers discover way to grow liver-like cells to test potential malaria drugs

In 2008, the World Health Organization announced a global effort to eradicate malaria, which kills about 800,000 people every year. As part of that goal, scientists are trying to develop new drugs that target the malaria parasite during the stage when it infects the human liver, which is crucial because some strains of malaria can lie dormant in the liver for several years before flaring up.

6 Feb 2015

Study shows that drinking green tea before taking supplements may reduce toxicity risk

As high doses of green tea extract supplements for weight loss become more popular, potential liver toxicity becomes a concern. In the last decade, dozens of people have been diagnosed with the condition. However, drinking green tea in the weeks before taking supplements likely reduces risk, according to researchers in Penn State's College of Agricultural Sciences.

5 Feb 2015

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Antibodies are now established as therapeutics and indispensable in the research lab. In con-trast to high-quality therapeutics, commercial antibodies used in research often do not proper-ly function, as an international group of authors around Andreas Plückthun of UZH have warned.

5 Feb 2015

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

5 Feb 2015

Resveratrol found in red grapes, peanuts may help prevent age-related decline in memory

A compound found in common foods such as red grapes and peanuts may help prevent age-related decline in memory, according to new research published by a faculty member in the Texas A&M Health Science Center College of Medicine.

5 Feb 2015

ISP shows promise in stopping fatal arrhythmias after heart attack

Case Western Reserve's chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack.

3 Feb 2015

Compound News and Research

UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

New compound appears to play role in development of opioid tolerance

Bacteria's DNA can pass trait to offspring in a way similar to parents' own DNA

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Experts discuss therapeutic potential of medical cannabis in a symposium organized by MUHC

Researchers develop new method for preventing destructive activity of osteoclasts

SRI Biosciences awarded contract to develop novel polymers to neutralize chemical, biological threats

New method of spectral analysis identifies fingerprints of chemical substances with greater accuracy

Researchers close to novel therapy to treat levodopa-induced dyskinesia

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Study: Simple blood test could predict risk of developing dementia

New findings could pave way to develop drug therapies for necrosis-related diseases

New compound may lead to development of potential therapeutics for neuropathic pain

41% of the British population unaware of the role of diet in cancer development

MIT engineers discover way to grow liver-like cells to test potential malaria drugs

Study shows that drinking green tea before taking supplements may reduce toxicity risk

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Resveratrol found in red grapes, peanuts may help prevent age-related decline in memory

ISP shows promise in stopping fatal arrhythmias after heart attack

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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