Cell News and Research

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EC grants orphan drug designation to TxCell's Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that the European Commission (EC) has granted orphan drug designation to TxCell's investigational medicinal product Col-Treg, a personalized T cell immunotherapy using collagen-II specific regulatory T-cells, for the treatment of autoimmune uveitis.

18 Dec 2014

New study identifies how SNAIL gene helps cancer cells break free from primary tumor

More than 90 percent of cancer-related deaths are caused by the spread of cancer cells from their primary tumor site to other areas of the body. A new study has identified how one important gene helps cancer cells break free from the primary tumor.

18 Dec 2014

Researchers identify a single protein as root cause of multiple allergic reactions

Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, they say, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV

17 Dec 2014

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

UCLA researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes.

17 Dec 2014

Researchers gain new insight into how motor neurons in the brain die during ALS

Researchers look to understand the causes of amyotrophic lateral sclerosis (ALS), in the hope of finding new ways to treat the disease. A new study published online today (December 17th) in the Cell Press journal Neuron shows that a common gene mutation in ALS generates a deadly protein that may cause the damage in the brain that leads to ALS.

17 Dec 2014

Postop chemotherapy supported for stage III NSCLC

Study findings challenge the belief that preoperative chemotherapy is superior to postoperative chemotherapy for patients with clinical stage III non-small-cell lung cancer.

17 Dec 2014

Metastatic RCC patients may benefit from sequential TKI strategy

For patients with metastatic renal cell carcinoma, sequential tyrosine kinase inhibitor therapy may be better option than changing to a mammalian target of rapamycin inhibitor, research suggests.

17 Dec 2014

RCC renal function independent of axitinib-induced proteinuria

Treatment with the vascular endothelial growth factor receptor inhibitor axitinib does not adversely affect renal function in patients with metastatic renal cell carcinoma even in the presence of proteinuria, a Japanese study indicates.

17 Dec 2014

Bruker Launches BioScope Resolve™ at the Sixth AFM BioMed Conference

Bruker unveiled the BioScope Resolve™, a biological atomic force microscope (bioAFM), at the sixth AFM BioMed Conference. The BioScope Resolve™ features excellent resolution imaging and comprehensive cell mechanics capabilities, and can be used with an inverted optical microscope (IOM).

From Bruker Nano Surfaces and Metrology 17 Dec 2014

Bacterial biofilms may increase colon cancer risk

Researchers from Johns Hopkins have found that dense mats of interacting bacteria, called biofilms, were present in the majority of cancers and polyps, particularly those on the right side of the colon. The presence of these bacterial bunches, they say, may represent an increased risk for colon cancer and could form the basis of new diagnostic tests.

17 Dec 2014

Two UH researchers named fellows of National Academy of Inventors

Two University of Houston faculty members have been named fellows of the National Academy of Inventors for their contributions to scientific and technological innovation.

17 Dec 2014

Investigational drug increases PFS in patients with advanced breast cancer

In a groundbreaking study that offers new hope for women with advanced breast cancer, researchers from UCLA's Jonsson Comprehensive Cancer Center have published final clinical trial results that showed the amount of time patients were on treatment without their cancer worsening (called progression-free survival) was effectively doubled in women with advanced breast cancer who took the experimental drug palbociclib.

17 Dec 2014

Research finding could inspire new ideas for treating type 2 oculocutaneous albinism

Newly published research provides the first demonstration of how a genetic mutation associated with a common form of albinism leads to the lack of melanin pigments that characterizes the condition.

17 Dec 2014

Mitochondrial DNA may predict overall risk of frailty, death

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

17 Dec 2014

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Eli Lilly and Company has received its third U.S. Food and Drug Administration approval for CYRAMZA (ramucirumab).

16 Dec 2014

Preclinical study strongly supports NT-113 as potential new treatment for glioblastoma multiforme

NewGen Therapeutics, Inc. today announced the publication of preclinical research strongly supporting NT-113, the company's novel irreversible pan-erbB inhibitor (EGFR, HER2 and HER4), as a potential new treatment for glioblastoma multiforme (GBM), the most common and most aggressive malignant primary brain tumor in adults.

16 Dec 2014

CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

CMC Biologics and OncoSynergy have entered into an agreement for process development and GMP manufacture of OS2966 – a novel potential treatment for Ebola. The investigational drug candidate, designed to inhibit a major cellular adhesion receptor (CD29) that is fundamental for progression of aggressive and resistant cancer tumors, was granted orphan drug designation by the U.S. FDA earlier this year in the treatment of glioblastoma.

16 Dec 2014

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

Novogen Limited, Australian/US biotechnology company, today announces that it has confirmed that its lead candidate product, TRXE-009, originally developed for the treatment of brain cancers, has been shown in pre-clinical studies also to be highly active against melanoma.

16 Dec 2014

Olympus BioScapes Digital Imaging Competition 2014 winners announced

From algae to zebrafish, life under the microscope can be beautiful, surprising and mysterious. This week, amazing glimpses of the unseen universe earned top prizes in the 2014 Olympus BioScapes Digital Imaging Competition®, the world’s foremost forum for showcasing microscope images of life science subjects.

From Evident Corporation - Life Sciences 16 Dec 2014

Scientists find new signal pathway that plays vital role in learning, processing of sensory input

Scientists at Johannes Gutenberg University Mainz in Germany have discovered a new signal pathway in the brain that plays an important role in learning and the processing of sensory input. It was already known that distinct glial cells receive information from neurons.

16 Dec 2014

Cell News and Research

EC grants orphan drug designation to TxCell's Col-Treg for treatment of autoimmune uveitis

New study identifies how SNAIL gene helps cancer cells break free from primary tumor

Researchers identify a single protein as root cause of multiple allergic reactions

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

Researchers gain new insight into how motor neurons in the brain die during ALS

Postop chemotherapy supported for stage III NSCLC

Metastatic RCC patients may benefit from sequential TKI strategy

RCC renal function independent of axitinib-induced proteinuria

Bruker Launches BioScope Resolve™ at the Sixth AFM BioMed Conference

Bacterial biofilms may increase colon cancer risk

Two UH researchers named fellows of National Academy of Inventors

Investigational drug increases PFS in patients with advanced breast cancer

Research finding could inspire new ideas for treating type 2 oculocutaneous albinism

Mitochondrial DNA may predict overall risk of frailty, death

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Preclinical study strongly supports NT-113 as potential new treatment for glioblastoma multiforme

CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

Olympus BioScapes Digital Imaging Competition 2014 winners announced

Scientists find new signal pathway that plays vital role in learning, processing of sensory input

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