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NTU scientists discover how malaria parasite develops resistance towards front-line drugs

Scientists from Nanyang Technological University have discovered exactly how the malaria parasite is developing resistance towards the most important front-line drugs used to treat the disease.

14 Dec 2014

Experts expose fundamental role of chaos and complexity in biological information processing

The interdisciplinary approach to problems that till recently were addressed in the hermetic framework of distinct disciplines such as physics, informatics, biology or sociology constitutes today one of the most active and innovative areas of science, where fundamental issues meet problems of everyday concern.

14 Dec 2014

Researchers uncover mechanism that helps white fat cells to become browner

White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern Denmark have uncovered the mechanism by which white fat cells from humans gets reprogrammed to become browner.

14 Dec 2014

Researchers assemble first high-resolution, 3-D maps of folded genomes

In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of "genomic origami" that allows the same genome to produce different types of cells. The research appears online today in Cell.

14 Dec 2014

Deoxygenated hemoglobin triggers conversion of nitrite to nitric oxide

Understanding how nitrite can improve conditions such as hypertension, heart attack and stroke has been the object of worldwide research studies. New research from Wake Forest University has potentially moved the science one step closer to this goal.

14 Dec 2014

New study finds that immune cells in the brain may contribute to obesity

Immune cells perform a previously unsuspected role in the brain that may contribute to obesity, according to a new study by UC San Francisco researchers.

14 Dec 2014

Pharmacyclics receives BayBio's 2014 Pantheon DiNA Award for Outstanding Company

Pharmacyclics, Inc. today announced that it has been awarded BayBio's 2014 Pantheon DiNA Award for Outstanding Company for its rapid development and commercialization of IMBRUVICA (ibrutinib). The award was presented at BayBio's 11th Annual Pantheon DiNA Awards ceremony in San Francisco.

13 Dec 2014

Figitumumab development discontinued for non-adenocarcinoma NSCLC

Adding the novel insulin-like growth factor 1 receptor inhibitor figitumumab to the epidermal growth factor receptor–tyrosine kinase inhibitor erlotinib does not improve survival in patients with non-adenocarcinoma non-small-cell lung carcinoma, research shows.

12 Dec 2014

Postoperative recurrent disease affects NSCLC survival after gefitinib

Patients with postoperative recurrent non-small-cell lung cancer harbouring epidermal growth factor receptor mutations have longer progression-free and overall survival with gefitinib treatment, than those with stage IV disease, Japanese researchers report.

12 Dec 2014

UR researchers on track to solve mystery of weight gain

University of Rochester researchers believe they're on track to solve the mystery of weight gain - and it has nothing to do with indulging in holiday eggnog.

12 Dec 2014

New evidence shows how personality affects health and wellbeing

Researchers have found new evidence that explains how some aspects of our personality may affect our health and wellbeing, supporting long-observed associations between aspects of human character, physical health and longevity.

12 Dec 2014

New statistical model enables better identification of different cell types in solid tumors

A new statistical model developed by a research team at Worcester Polytechnic Institute may enable physicians to create personalized cancer treatments for patients based on the specific genetic mutations found in their tumors.

12 Dec 2014

Young patients at risk for intellectual decline after bone marrow transplantation

Toddlers who undergo total body irradiation in preparation for bone marrow transplantation are at higher risk for a decline in IQ and may be candidates for stepped up interventions to preserve intellectual functioning, St. Jude Children's Research Hospital investigators reported.

12 Dec 2014

Research finding could lead to new therapies for malignant glioma

Targeted therapies are a growing and groundbreaking field in cancer care in which drugs or other substances are designed to interfere with genes or molecules that control the growth and survival of cancer cells. Now, scientists at Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine (VIMM) have identified a novel interaction between a microRNA and a gene that could lead to new therapies for the most common and deadly form of brain tumor, malignant glioma.

12 Dec 2014

Three studies reveal effects of blocking androgen receptors in breast cancer

Three studies presented by University of Colorado Cancer Center researchers at the San Antonio Breast Cancer Symposium 2014 demonstrate the effects of blocking androgen receptors in breast cancer.

12 Dec 2014

IRCM researchers uncover mechanism that regulates dopamine levels in the brain

Researchers in Montréal led by Jacques Drouin, D.Sc., uncovered a mechanism regulating dopamine levels in the brain by working on a mouse model of late onset Parkinson's disease.

12 Dec 2014

MSU researchers find possible way to boost healthy cell production in cancer patients during chemo

Michigan State University scientists are closer to discovering a possible way to boost healthy cell production in cancer patients as they receive chemotherapy. By adding thymine - a natural building block found in DNA - into normal cells, they found it stimulated gene production and caused them to multiply.

12 Dec 2014

BGI Diagnostics develops ‘education hub’ to raise awareness about non-invasive prenatal testing

provider of accurate, reliable and affordable genetic tests and molecular diagnostics services has demonstrated its commitment to raising awareness about non-invasive prenatal testing (NIPT) by developing a dedicated ‘education hub’ as part of its new, highly informative website.

12 Dec 2014

Brunel scientists find way to target hard-to-reach cancers using 'Trojan horse' nanoparticles

Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment normally brings.

12 Dec 2014

First-line dacomitinib may improve advanced NSCLC survival

Preliminary research suggests that the second-generation tyrosine kinase inhibitor dacomitinib may improve progression-free survival in patients with advanced non-small-cell lung cancer with epidermal growth factor receptor mutations.

11 Dec 2014

Cell News and Research

NTU scientists discover how malaria parasite develops resistance towards front-line drugs

Experts expose fundamental role of chaos and complexity in biological information processing

Researchers uncover mechanism that helps white fat cells to become browner

Researchers assemble first high-resolution, 3-D maps of folded genomes

Deoxygenated hemoglobin triggers conversion of nitrite to nitric oxide

New study finds that immune cells in the brain may contribute to obesity

Pharmacyclics receives BayBio's 2014 Pantheon DiNA Award for Outstanding Company

Figitumumab development discontinued for non-adenocarcinoma NSCLC

Postoperative recurrent disease affects NSCLC survival after gefitinib

UR researchers on track to solve mystery of weight gain

New evidence shows how personality affects health and wellbeing

New statistical model enables better identification of different cell types in solid tumors

Young patients at risk for intellectual decline after bone marrow transplantation

Research finding could lead to new therapies for malignant glioma

Three studies reveal effects of blocking androgen receptors in breast cancer

IRCM researchers uncover mechanism that regulates dopamine levels in the brain

MSU researchers find possible way to boost healthy cell production in cancer patients during chemo

BGI Diagnostics develops ‘education hub’ to raise awareness about non-invasive prenatal testing

Brunel scientists find way to target hard-to-reach cancers using 'Trojan horse' nanoparticles

First-line dacomitinib may improve advanced NSCLC survival

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