Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists show how 'dormant virus' causes cancer

Cancer Research UK scientists have revealed how a dormant virus triggers a type of cancer found in young people, according to research published in PLoS Pathogens.

15 Mar 2009

Discovery of master regulator of motor neuron firing

When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation.

15 Mar 2009

A model of melanoma generates hope for the use of targeted therapies

Researchers have developed a new mouse model that allows them to replicate normal pigment cells at the earliest stages of conversion to malignant skin cancer in humans.

12 Mar 2009

New drug derived from magnolia trees proves safe, tolerable in preventing blood clots

A new drug derived from magnolia trees appears to be able to uncouple two important functions of thrombin in blood clot formation and may offer a way to better control the potentially dangerous complications of bleeding and clot formation during procedures to open blocked coronary arteries, say researchers at the Duke Clinical Research Institute (DCRI).

12 Mar 2009

AMP-activated protein kinase essential contributor to brain growth

An enzyme researchers have studied for years because of its potential connections to cancer, diabetes, heart disease, hypertension and stroke, appears to have yet another major role to play: helping create and maintain the brain.

12 Mar 2009

Discovery may lead to immunosuppressant drugs that have fewer adverse side effects

Immunosuppressive treatment is necessary to prevent rejection of an organ after transplant and has great potential for treating chronic inflammatory diseases.

12 Mar 2009

Cells get two chances, not just one, to fix their mistakes

Cells have two chances to fix the same mistake in their protein-making process instead of just one - a so-called proofreading step - that had previously been identified, according to new research.

12 Mar 2009

Body clock regulates energy levels in cells

UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells.

12 Mar 2009

Protein 'magnet' uncovers clue to cancer cell spread

The destruction of a protein 'magnet' could lead to cancer cells breaking away from a tumour and spreading around the body, according to a study in Molecular Cell today (Thursday).

12 Mar 2009

New project to develop blood tests for heart disease and stroke

The landmark Framingham Heart Study (FHS) is launching a major initiative to discover risk factors and markers that could lead to new blood tests to identify individuals at high risk of heart disease and stroke.

12 Mar 2009

AMP-activated protein kinase is unexpected contributor to brain growth

12 Mar 2009

Test successfully identifies arrhythmogenic right ventricular cardiomyopathy

11 Mar 2009

A blood test for Alzheimer's on the horizon

Researchers have revealed a direct relationship between two specific antibodies and the severity of Alzheimer's disease symptoms, raising hopes that a diagnostic blood test for the devastating disorder is within reach.

11 Mar 2009

Scientists unveil a new path towards better immune responses

The immune response can protect us from basically any invader but it can also create disease - like it happens in autoimmunity where it attacks the own body - so to understand its regulation is an important tool to assure its proper functioning.

11 Mar 2009

Discovery of new pathway that regulates inflammation

Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens.

11 Mar 2009

Study of Rituxan (rituximab) in lupus nephritis misses primary endpoint

Genentech, Inc. and Biogen Idec has announced that a Phase III study of Rituxan (rituximab) plus mycophenolate mofetil (MMF) and corticosteroids in patients with lupus nephritis did not meet its primary endpoint of significantly reducing disease activity at 52 weeks.

11 Mar 2009

Novel anti-inflammatory therapy protects lungs from runaway inflammation

A novel anti-inflammatory therapy designed by Vanderbilt University Medical Center investigators prevents acute lung injury in mice exposed to an inflammation-causing toxin, the researchers report in the journal Molecular Therapy.

11 Mar 2009

New test successfully identifies arrhythmogenic right ventricular cardiomyopathy

A study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that a new immunohistochemical test is reliable in diagnosing a dangerous arrhythmic heart disease known as arrhythmogenic right ventricular cardiomyopathy (ARVC.) Reported in the March 12 issue of The New England Journal of Medicine ( NEJM ), the new findings offer the possibility of a highly sensitive and specific means of identifying this life- threatening condition at an early stage, when it can be treated with by implanting a cardiac defibrillator.

11 Mar 2009

Anesthesia or hypothermia: Warning for Alzheimer's patients

Everyone knows that its important to keep a cool head, but a new study published online in The FASEB Journal shows that for Alzheimer's patients, a cool head may make the disease worse.

11 Mar 2009

Alzheimer's marker amyloid beta 42 linked to brain damage

Researchers at Washington University School of Medicine in St. Louis have linked a potential indicator of Alzheimer's disease to brain damage in humans with no signs of mental impairment.

11 Mar 2009