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Prenatal androgen exposure may influence girls' interests, but not gender identity or playmates

Prenatal exposure to male hormones influences which activities girls are interested and engage in, but the effects of those hormones don't extend to gender identity or who they socialize with, according to Penn State researchers.

2 Mar 2018

Study provides insight into mechanisms for increased male susceptibility to ASD

Exposure to androgens (male hormones) during brain development alters genes related to autism spectrum disorder (ASD), according to a new study published in Biological Psychiatry.

7 Feb 2018

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Men with type 2 diabetes are less likely to develop prostate cancer than patients without diabetes. However, the mortality rate is higher.

31 Jan 2018

Women with PCOS likely to have less diverse gut bacteria, study reveals

Women who have a common hormone condition that contributes to infertility and metabolic problems tend to have less diverse gut bacteria than women who do not have the condition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

23 Jan 2018

Research: Men who lack HSD17B4 gene may be more susceptible to treatment-resistant prostate cancer

Cleveland Clinic researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate cancer.

17 Jan 2018

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

A new blood stabilization method, developed at the Massachusetts General Hospital Center for Engineering in Medicine, significantly prolongs the lifespan of blood samples for microfluidic sorting and transcriptome profiling of rare circulating tumor cells (CTCs), living cancer cells carried in the bloodstream.

9 Jan 2018

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Study findings highlight importance of screening PCOS patients for mental health disorders

Women with PCOS are more likely to suffer from mental health disorders and should be routinely screened for these during medical assessments, according to a study presented at the Society for Endocrinology annual conference in Harrogate.

6 Nov 2017

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

New research from North Carolina State University reveals that prenatal exposure to bisphenol A (BPA) at levels below those currently considered safe for humans affects gene expression related to sexual differentiation and neurodevelopment in the developing rat brain.

31 Oct 2017

New study describes unique role of androgens in kidney cancer

A new study is believed to be the first to describe the unique role of androgens in kidney cancer, and it suggests that a new approach to treatment, targeting the androgen receptor (AR), is worth further investigation.

13 Oct 2017

UIC study receives $3 million federal grant to study effects of inflammation on PCOS

The University of Illinois at Chicago has received a $3 million federal grant to study the effects of inflammation on polycystic ovary syndrome, or PCOS.

10 Oct 2017

Scientists unravel mechanism that links gut bacteria to hypertension

One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk.

3 Oct 2017

New study reveals impact of Agent Orange exposure on women and babies in Vietnam

Exposure to Agent Orange sprayed during the Vietnam War has been linked to increased levels of certain hormones in women and their breastfeeding children decades later, potentially putting them at higher risk of health problems, according to a new study in Science of the Total Environment.

26 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

Phthalate levels in expectant fathers influence sperm epigenetics, study suggests

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples' reproductive success via epigenetic modifications of sperm DNA.

12 Sep 2017

Two new treatments may benefit patients with high risk prostate cancer, trial shows

Patients with high risk prostate cancer starting long-term hormone therapy may benefit from two new treatments, according to late-breaking results from the STAMPEDE trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Bariatric surgery in men linked to frequent sperm aberrations and lower fertility rates

A meta-analysis of studies in which men underwent Roux-en-Y gastric bypass (RYGB) procedures found frequent sperm aberrations and lower fertility rates despite improvements in weight, androgen levels, and sexual quality of life following the procedure.

8 Sep 2017

Women with PCOS have higher risk of developing type 2 diabetes, study reveals

Women who have polycystic ovary syndrome (PCOS) have a higher risk of developing type 2 diabetes (T2D) and are diagnosed at an earlier age with the condition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

29 Aug 2017

New blood test can predict drug resistance in patients with advanced prostate cancer

When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that renders them resistant to particular medications.

22 Aug 2017